C7R0A3 (C7R0A3_JONDD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
L-arabinose isomerase HAMAP MF_00519
EC=5.3.1.4 HAMAP MF_00519

Gene names

Name:	araA HAMAP MF_00519
Ordered Locus Names:	Jden_0498

Organism

Jonesia denitrificans (strain ATCC 14870 / DSM 20603 / CIP 55134) (Listeria denitrificans) [Complete proteome] [HAMAP]

Taxonomic identifier

471856 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Jonesiaceae › Jonesia

Protein attributes

Sequence length	502 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity. HAMAP MF_00519 SAAS SAAS003762
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519 SAAS SAAS003762
Cofactor	Binds 1 manganese ion per subunit By similarity. HAMAP MF_00519 SAAS SAAS003762
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519 SAAS SAAS003762
Sequence similarities	Belongs to the arabinose isomerase family. HAMAP MF_00519

Ontologies

Keywords
Biological process	Arabinose catabolism HAMAP MF_00519 SAAS SAAS003762 Carbohydrate metabolism
Ligand	Manganese HAMAP MF_00519 SAAS SAAS003762 Metal-binding HAMAP MF_00519 SAAS SAAS003762
Molecular function	Isomerase HAMAP MF_00519 SAAS SAAS003762 EMBL ACV08162.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: HAMAP fucose metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: HAMAP L-fucose isomerase activity Inferred from electronic annotation. Source: InterPro manganese ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	307	1	Manganese By similarity HAMAP MF_00519
	Metal binding	334	1	Manganese By similarity HAMAP MF_00519
	Metal binding	351	1	Manganese By similarity HAMAP MF_00519
	Metal binding	450	1	Manganese By similarity HAMAP MF_00519

Sequences

	Sequence		Length	Mass (Da)
	C7R0A3 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: 0294740899422894	FASTA	502	55,372
	10 20 30 40 50 60 MNNPFEGKEI WFLTGSQDLY GEETLAQVAE QSQALVSLID GADSIPVKVV WKPVLKDSDS 70 80 90 100 110 120 IRRAMLDANS DDSCIGLIAW MHTFSPAKMW IRGLDALTVP LLHLHTQANV ELPWSTIDMD 130 140 150 160 170 180 FMNLNQAAHG DREFAYIQSR MNVQRKIVSG HPSDDTVLSE IAAWSRAAAG WNEAQSMRVA 190 200 210 220 230 240 RFGDNMRNVA VTEGDKTEAE ISLGVSVNTW PVNELVDAVD AVSQSDIDAL VAEYEELYDV 250 260 270 280 290 300 QEELRRGGDR HDSLRYGAAI EIALRGFLEA GKFGAFTTNF EDLGGLRQLP GLAVQRLMAD 310 320 330 340 350 360 GYGFGAEGDW KTAVLVRIAK VMGYGLPGGA SLMEDYTYDL TPGSELILGA HMLEVCPSLT 370 380 390 400 410 420 TDKPRLEIHP LGIGGKEDPV RLVFTADAGP AVVVAMSDMR ERFRLVVNVV TNVDAPQELP 430 440 450 460 470 480 NLPVARAVWQ PEPSFKVSTQ AWLLTGAAHH TCMDTAASLD TWLDFAQIAQ TELVVIDEKT 490 500 EIRQFAQELR WNQAYYRLAQ GF

References

[1]

"Complete genome sequence of Jonesia denitrificans type strain (Prevot 55134)." Pukall R., Gehrich-Schroter G., Lapidus A., Nolan M., Glavina Del Rio T., Lucas S., Chen F., Tice H., Pitluck S., Cheng J.F., Copeland A., Saunders E., Brettin T., Detter J.C., Bruce D., Goodwin L., Pati A., Ivanova N. , Mavromatis K., Ovchinnikova G., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Chain P., Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P., Han C. Stand. Genomic Sci. 1:262-269(2009) [PubMed: 21304666] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 14870 / DSM 20603 / CIP 55134.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001706 Genomic DNA. Translation: ACV08162.1.
RefSeq	YP_003160465.1. NC_013174.1.
3D structure databases
ProteinModelPortal	C7R0A3.
ModBase	Search...
Protein-protein interaction databases
STRING	C7R0A3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8379683.
GenomeReviews	Gene locus Jden_0498 in contig CP001706_GR.
KEGG	jde:Jden_0498.
PATRIC	22161006. VBIJonDen9837_0516.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EVCPTIA.
ProtClustDB	PRK02929.
Family and domain databases
HAMAP	MF_00519. Arabinose_Isome. [Tree]
InterPro	IPR024664. Ara_Isoase_C. IPR004216. Fuc/Ara_isomerase_C. IPR009015. Fucose_isomerase_N/cen. IPR003762. Lara_isomerase. [Graphical view]
KO	K01804.
Pfam	PF11762. Arabinose_Iso_C. 1 hit. PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF50443. Fuc_isomerase_C. 1 hit. SSF53743. Fuc_isomerase_N. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C7R0A3_JONDD

Accession

Primary (citable) accession number: C7R0A3

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)