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Protein

Xylose isomerase

Gene

xylA

Organism
Jonesia denitrificans (strain ATCC 14870 / DSM 20603 / CIP 55134) (Listeria denitrificans)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei51UniRule annotation1
Active sitei54UniRule annotation1
Metal bindingi178Magnesium 1UniRule annotation1
Metal bindingi214Magnesium 1UniRule annotation1
Metal bindingi214Magnesium 2UniRule annotation1
Metal bindingi217Magnesium 2UniRule annotation1
Metal bindingi242Magnesium 1UniRule annotation1
Metal bindingi292Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processCarbohydrate metabolism, Xylose metabolismUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciJDEN471856:G1GFQ-460-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Jden_0466Imported
OrganismiJonesia denitrificans (strain ATCC 14870 / DSM 20603 / CIP 55134) (Listeria denitrificans)Imported
Taxonomic identifieri471856 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesJonesiaceaeJonesia
Proteomesi
  • UP000000628 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi471856.Jden_0466

Structurei

3D structure databases

ProteinModelPortaliC7R071
SMRiC7R071
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 262AP_endonuc_2InterPro annotationAdd BLAST225

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
HOGENOMiHOG000022596
KOiK01805
OMAiNQLAIEH
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
IPR013453 XylA_actinobac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02631 xylA_Arthro, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

C7R071-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQQDIKYSF GLWTTGWQGR DQFGDATRAF RSPADDVRKL AELGAWGFTF
60 70 80 90 100
HDDDVVPFGS DDATRAKLLG EVKDAAQETG LTIEMVTTNL FSHPVFKDGG
110 120 130 140 150
VTSNDRSVRR FALRKVLRNV DLTAELGAKT FVMWGGREGS EYDGAKDLHA
160 170 180 190 200
ALERYKEGVD LIAGYIKEKG YDIKIALEPK PNEPRGDIFL PTVGHALGFI
210 220 230 240 250
AELEHGDIVG LNPETGHEQM AGLNYTHGLA QALWADKLFH IDLNGQRSIK
260 270 280 290 300
FDQDLVFGHG DLLSAFFTVD LVENGFPASP DAPRYTGPRH FDYKPSRTEA
310 320 330 340 350
VEGVWDSAKA NMETYNLLAA KAKAYREDPE VKAAMEQAGL FELATPTLAA
360 370 380 390
GESVADLLAD TSAFEDFDAD AAAERSFGFV RLNQLAIKHL IG
Length:392
Mass (Da):43,081
Last modified:October 13, 2009 - v1
Checksum:i04EE3A1706D36B36
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001706 Genomic DNA Translation: ACV08130.1
RefSeqiWP_015770759.1, NC_013174.1

Genome annotation databases

EnsemblBacteriaiACV08130; ACV08130; Jden_0466
KEGGijde:Jden_0466

Similar proteinsi

Entry informationi

Entry nameiC7R071_JONDD
AccessioniPrimary (citable) accession number: C7R071
Entry historyiIntegrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: April 25, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health