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C7QYT8 (C7QYT8_JONDD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047
EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Jden_1680
OrganismJonesia denitrificans (strain ATCC 14870 / DSM 20603 / CIP 55134) (Listeria denitrificans) [Complete proteome] [HAMAP]
Taxonomic identifier471856 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Jonesiaceae › Jonesia ›

Protein attributes

Sequence length389 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. SAAS SAAS005905 HAMAP-Rule MF_00047

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. SAAS SAAS005905 HAMAP-Rule MF_00047

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. SAAS SAAS005905 HAMAP-Rule MF_00047

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. SAAS SAAS005905 HAMAP-Rule MF_00047

Subcellular location

Cytoplasm By similarity SAAS SAAS005905 HAMAP-Rule MF_00047.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. SAAS SAAS005905 HAMAP-Rule MF_00047

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain168 – 379212ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding200 – 25556ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3331Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3461Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3461Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3481Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
C7QYT8 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 26959C787BC7A099

FASTA38941,494
        10         20         30         40         50         60 
MENMSTSQTR PNNLGAPHAA DRVRTRVLVL FGGRSGEHPI SCITAAGVLR AIDRDRFDVV 

        70         80         90        100        110        120 
AVGITQGGKW VLASTDPDEV VTSGDDLPHV ADNGTEVLLP FASGDNEVRV IRDGVLESVG 

       130        140        150        160        170        180 
PVDVVLPLLH GPFGEDGTVQ GMLELADLRY VGVGVLGSAV GMDKHYMKLV FEGHGLPVGP 

       190        200        210        220        230        240 
YTTVFPGQWQ RDPDEVRARV VALGLPVFVK PTRAGSSLGI SKVSDVGDLD RAMAEALKHD 

       250        260        270        280        290        300 
PKVIIEAGIV GREIECAVLG GHGDTPARAS LPGEITMTGS AHEFYDFEAK YLDDASAQLS 

       310        320        330        340        350        360 
CPAELDETTT ATVREVAVRA FDAVGGEGLS RVDVFVQEDG AVVVNEINTM PGFTPISMYP 

       370        380 
RMWERSGVSY TELISELIDL ALERPLGLR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001706 Genomic DNA. Translation: ACV09327.1.
RefSeqYP_003161630.1. NC_013174.1.

3D structure databases

ProteinModelPortalC7QYT8.
ModBaseSearch...

Protein-protein interaction databases

STRING471856.Jden_1680.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACV09327; ACV09327; Jden_1680.
GeneID8380848.
KEGGjde:Jden_1680.
PATRIC22163549. VBIJonDen9837_1754.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
HOGENOMHOG000011593.
KOK01921.
OMALLHGPFG.
ProtClustDBCLSK2818721.

Enzyme and pathway databases

BioCycJDEN471856:GH77-1648-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC7QYT8_JONDD
AccessionPrimary (citable) accession number: C7QYT8
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info