C7QT21 (C7QT21_CYAP0) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase HAMAP MF_00387
Short name=UDP-N-acetylglucosamine acyltransferase HAMAP MF_00387
EC=2.3.1.129 HAMAP MF_00387

Gene names

Name:	lpxA HAMAP MF_00387
Ordered Locus Names:	Cyan8802_1683

Organism

Cyanothece sp. (strain PCC 8802) (Synechococcus sp. (strain RF-2)) [Complete proteome] [HAMAP] EMBL ACV00587.1

Taxonomic identifier

395962 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Cyanothece

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00387
Catalytic activity	(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. HAMAP MF_00387
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. HAMAP MF_00387
Subunit structure	Homotrimer By similarity. HAMAP MF_00387
Subcellular location	Cytoplasm By similarity HAMAP MF_00387.
Sequence similarities	Belongs to the transferase hexapeptide repeat family. LpxA subfamily. HAMAP MF_00387

Ontologies

Keywords
Biological process	Lipid A biosynthesis HAMAP MF_00387 Lipid synthesis
Cellular component	Cytoplasm HAMAP MF_00387
Domain	Repeat HAMAP MF_00387
Molecular function	Acyltransferase HAMAP MF_00387 EMBL ACV00587.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C7QT21 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: AE09D5F8FBA8B788	FASTA	276	30,071
	10 20 30 40 50 60 MLTDQSKRDA LLNTHIHPTA VIHPKAELHP TVTVGPYAVI GENVKIGAQT TIGAHAVIEG 70 80 90 100 110 120 PIEIGIGNRI FPSAVIGLEP QDLKYKGAAS WVKIGDYNTI REFVTINRAT HADEVTEIGS 130 140 150 160 170 180 HNLLMAYVHV AHNCVIEDHV IIANAVALAG HVHIESRAVI GGALGVHQFV RIGRNAMLGG 190 200 210 220 230 240 MSRIDRDAPP YMAVEGNPSR VRALNLIGLK RAGLTAEDLS SLKKAFRLLY RSQLTFKEAL 250 260 270 EELQALSNNQ YVEYLYQFLQ ASTTGEKRRG PIPGKN

References

[1]

"Complete sequence of chromosome of Cyanothece sp. PCC 8802." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Meincke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N. , Mikhailova N., Pakrasi H.B., Sherman L. Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 8802.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001701 Genomic DNA. Translation: ACV00587.1.
RefSeq	YP_003137422.1. NC_013161.1.
3D structure databases
ProteinModelPortal	C7QT21.
ModBase	Search...
Protein-protein interaction databases
STRING	C7QT21.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8390995.
GenomeReviews	Gene locus Cyan8802_1683 in contig CP001701_GR.
KEGG	cyh:Cyan8802_1683.
PATRIC	21584882. VBICyaSp112625_1769.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	REFCTFN.
PhylomeDB	C7QT21.
ProtClustDB	PRK05289.
Family and domain databases
HAMAP	MF_00387. LpxA. [Tree]
InterPro	IPR001451. Hexapep_transf. IPR018357. Hexapep_transf_CS. IPR010137. Lipid_A_lpxA. IPR011004. Trimer_LpxA-like. [Graphical view]
KO	K00677.
Pfam	PF00132. Hexapep. 3 hits. [Graphical view]
PIRSF	PIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAM	SSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMs	TIGR01852. Lipid_A_lpxA. 1 hit.
PROSITE	PS00101. HEXAPEP_TRANSFERASES. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C7QT21_CYAP0

Accession

Primary (citable) accession number: C7QT21

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)