C7QQZ1 (C7QQZ1_CYAP0) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
GTPase Der RuleBase RU004481 HAMAP-Rule MF_00195

Alternative name(s):
GTP-binding protein EngA HAMAP-Rule MF_00195

Gene names

Name:	der HAMAP-Rule MF_00195
Ordered Locus Names:	Cyan8802_0118 EMBL ACU99088.1

Organism

Cyanothece sp. (strain PCC 8802) (Synechococcus sp. (strain RF-2)) [Complete proteome] [HAMAP] EMBL ACU99088.1

Taxonomic identifier

395962 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Cyanothece

Protein attributes

Sequence length	452 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	GTPase that plays an essential role in the late steps of ribosome biogenesis By similarity. RuleBase RU004481 HAMAP-Rule MF_00195 SAAS SAAS016484
Subunit structure	Associates with the 50S ribosomal subunit By similarity. HAMAP-Rule MF_00195 SAAS SAAS016484
Sequence similarities	Belongs to the Era/MnmE GTP-binding protein family. Der subfamily. RuleBase RU004481 HAMAP-Rule MF_00195 Contains 1 KH-like domain. HAMAP-Rule MF_00195 SAAS SAAS016484 Contains 2 G (guanine nucleotide-binding) domains. HAMAP-Rule MF_00195 SAAS SAAS016484

Ontologies

Keywords
Biological process	Ribosome biogenesis HAMAP-Rule MF_00195 SAAS SAAS016484
Domain	Repeat RuleBase RU004481 HAMAP-Rule MF_00195 SAAS SAAS016484
Ligand	GTP-binding HAMAP-Rule MF_00195 SAAS SAAS016484 RuleBase RU003312 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ribosome biogenesis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	GTP binding Inferred from electronic annotation. Source: HAMAP nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Domain	6 – 121	116	G 1 By similarity HAMAP-Rule MF_00195
	Domain	178 – 296	119	G 2 By similarity HAMAP-Rule MF_00195
	Domain	352 – 438	87	KH-like By similarity HAMAP-Rule MF_00195
	Nucleotide binding	10 – 17	8	GTP 1 By similarity HAMAP-Rule MF_00195
	Nucleotide binding	57 – 61	5	GTP 1 By similarity HAMAP-Rule MF_00195
	Nucleotide binding	120 – 123	4	GTP 1 By similarity HAMAP-Rule MF_00195
	Nucleotide binding	183 – 190	8	GTP 2 By similarity HAMAP-Rule MF_00195
	Nucleotide binding	230 – 234	5	GTP 2 By similarity HAMAP-Rule MF_00195
	Nucleotide binding	295 – 298	4	GTP 2 By similarity HAMAP-Rule MF_00195

Sequences

	Sequence		Length	Mass (Da)
	C7QQZ1 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: 6BDCD49CD2D679BA	FASTA	452	50,772
	10 20 30 40 50 60 MPLPIVAIIG RPNVGKSTLA NRLAGDQHAI VHDEPGITRD RTYRPGFWQD RDFQIVDTGG 70 80 90 100 110 120 LVFDDDTEFL PLIREQSLAA LNEASAAIFV VDGQTGPTTG DLEIADWLRQ QPVPVLLAVN 130 140 150 160 170 180 KCESPELGLI QATQFWELGL GNPYPISGIH GNGTGELLDD LITYLPPPEE ITQSDEIKVA 190 200 210 220 230 240 IIGRPNVGKS SLLNALLGEN RAIVSPISGT TRDAIDTVIQ HNEQTYRLID TAGIRRKKNV 250 260 270 280 290 300 EYGAEFFSIN RAFKAIRRCD VVLFVIDAID GVTDQDLKLA DRIIEEGRSV VLVINKWDAV 310 320 330 340 350 360 DKDSYTIYEY KTNIFSRLYF MEWAPIIFVS AMTGQRVNKI LELVNSSTEE HRRRVTTAVI 370 380 390 400 410 420 NEVLQEAVTW HSPPTTRQGK QGKIYYGTQV STQPPTIALF VNDPKRFNEN YRRYIESQFR 430 440 450 KQLGFPGTPI RLLWRGKKVR EVEQSANRAT KV

References

[1]

"Novel metabolic attributes of the genus Cyanothece, comprising a group of unicellular nitrogen-fixing Cyanobacteria." Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H., Sherman L.A., Pakrasi H.B. MBio 2:E214-E214(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 8802.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001701 Genomic DNA. Translation: ACU99088.1.
RefSeq	YP_003135924.1. NC_013161.1.
3D structure databases
ProteinModelPortal	C7QQZ1.
ModBase	Search...
Protein-protein interaction databases
STRING	395962.Cyan8802_0118.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACU99088; ACU99088; Cyan8802_0118.
GeneID	8389421.
KEGG	cyh:Cyan8802_0118.
PATRIC	21581715. VBICyaSp112625_0196.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1160.
HOGENOM	HOG000242861.
KO	K03977.
OMA	YLENTYR.
ProtClustDB	PRK00093.
Enzyme and pathway databases
BioCyc	CSP395962:GJC3-118-MONOMER.
Family and domain databases
Gene3D	3.30.300.20. 1 hit.
HAMAP	MF_00195. GTPase_Der.
InterPro	IPR003593. AAA+_ATPase. IPR016484. GTP-bd_EngA. IPR006073. GTP_binding_domain. IPR015946. KH_dom-like_a/b. IPR005225. Small_GTP-bd_dom. [Graphical view]
PANTHER	PTHR11649:SF5. PTHR11649:SF5. 1 hit.
Pfam	PF01926. MMR_HSR1. 2 hits. [Graphical view]
PIRSF	PIRSF006485. GTP-binding_EngA. 1 hit.
PRINTS	PR00326. GTP1OBG.
SMART	SM00382. AAA. 2 hits. [Graphical view]
TIGRFAMs	TIGR03594. GTPase_EngA. 1 hit. TIGR00231. small_GTP. 2 hits.
ProtoNet	Search...

Entry information

Entry name

C7QQZ1_CYAP0

Accession

Primary (citable) accession number: C7QQZ1

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)