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C7QAZ9

- C7QAZ9_CATAD

UniProt

C7QAZ9 - C7QAZ9_CATAD

Protein

UvrABC system protein C

Gene

uvrC

Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (13 Oct 2009)
      Previous versions | rss
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    Functioni

    The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotationSAAS annotation

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-HAMAP
    2. excinuclease ABC activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. nucleotide-excision repair Source: UniProtKB-HAMAP
    2. SOS response Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Excision nucleaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    DNA damage, DNA excisionUniRule annotationSAAS annotation, DNA repair, SOS responseUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciCACI479433:GI6Z-5649-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UvrABC system protein CUniRule annotation
    Short name:
    Protein UvrCUniRule annotation
    Alternative name(s):
    Excinuclease ABC subunit CUniRule annotation
    Gene namesi
    Name:uvrCUniRule annotation
    Ordered Locus Names:Caci_5613Imported
    OrganismiCatenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)Imported
    Taxonomic identifieri479433 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCatenulisporineaeCatenulisporaceaeCatenulispora
    ProteomesiUP000000851: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. excinuclease repair complex Source: InterPro

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Interacts with UvrB in an incision complex.UniRule annotationSAAS annotation

    Protein-protein interaction databases

    STRINGi479433.Caci_5613.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini16 – 9580GIY-YIGUniRule annotationAdd
    BLAST
    Domaini208 – 24336UVRUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the UvrC family.UniRule annotation
    Contains 1 GIY-YIG domain.UniRule annotation
    Contains 1 UVR domain.UniRule annotation
    Contains GIY-YIG domain.SAAS annotation
    Contains UVR domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG0322.
    HOGENOMiHOG000279962.
    KOiK03703.
    OMAiAMHEVIT.
    OrthoDBiEOG6K13R9.

    Family and domain databases

    Gene3Di3.40.1440.10. 1 hit.
    4.10.860.10. 1 hit.
    HAMAPiMF_00203. UvrC.
    InterProiIPR027299. GIY-YIG_dom.
    IPR000305. GIY-YIG_SF.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR010994. RuvA_2-like.
    IPR001943. UVR_dom.
    IPR004791. UvrC.
    IPR001162. UvrC_homol_region.
    [Graphical view]
    PfamiPF01541. GIY-YIG. 1 hit.
    PF02151. UVR. 1 hit.
    PF08459. UvrC_HhH_N. 1 hit.
    [Graphical view]
    SMARTiSM00465. GIYc. 1 hit.
    SM00278. HhH1. 2 hits.
    [Graphical view]
    SUPFAMiSSF46600. SSF46600. 1 hit.
    SSF47781. SSF47781. 1 hit.
    SSF82771. SSF82771. 1 hit.
    TIGRFAMsiTIGR00194. uvrC. 1 hit.
    PROSITEiPS50164. GIY_YIG. 1 hit.
    PS50151. UVR. 1 hit.
    PS50165. UVRC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C7QAZ9-1 [UniParc]FASTAAdd to Basket

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    MADPATYRPK PGEIPTSPGV YKFRDPHSRV IYVGKAKNLR SRLTSYFQDL    50
    ANLHVRTQTM VTTAASVEWT TVATEVEALQ LEYTWIKQFE PRFNVKYRDD 100
    KSYPSLAVTV GEEFPRAQVM RGPKRPGVRY FGPYSHAWAI RETLDSLLRV 150
    FPIRTCSSGV FKRAAQTGRP CLLGYIGKCS APCVGRVSAE EHREIVDDFV 200
    SFMAGRTDRY IRGLEEEMKE AAKELEFEKA ARLRDDLQAL KQSLEKNAVV 250
    LGDGTDADVI ALSEDPLEAA VQVFHVRGGR IRGQRGWVVD RVEDVDTAGL 300
    VEHFMQQLYG SEQGEPGIDT ETVPREILVP ELPGSVEAIT EWLSARRGAK 350
    VEVRIPKRGD KAALMETVAQ NAKQALALHK TRRASDLTTR SVALQELADA 400
    IGMDQAPLRI ECYDISHLQG TNVVASMVVF EDGLPRKSEY RRFTIKGSDE 450
    NGATNDDVRN MHEVITRRFK AFLKEQEEEK LIDATIGDRK KFSYPPQLVV 500
    VDGGQPQVAA AARALADLEI SDVTLVGLAK RLEEVWLPDE DDPVLLPRSS 550
    EGLYMLQRVR DEAHRFGIAF HRQKRSKSMV ASALDDVPGL GEVRRKALLA 600
    HFGTLRKLRA AQVAEIAEVP GIGPATARQI HSALAELPVS RAVNAATGEI 650
    LDGGESRNGP DEE 663
    Length:663
    Mass (Da):73,646
    Last modified:October 13, 2009 - v1
    Checksum:iA00C377ADDCB83A7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001700 Genomic DNA. Translation: ACU74472.1.
    RefSeqiWP_015794201.1. NC_013131.1.
    YP_003116313.1. NC_013131.1.

    Genome annotation databases

    EnsemblBacteriaiACU74472; ACU74472; Caci_5613.
    GeneIDi8336973.
    KEGGicai:Caci_5613.
    PATRICi21289927. VBICatAci36872_5711.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001700 Genomic DNA. Translation: ACU74472.1 .
    RefSeqi WP_015794201.1. NC_013131.1.
    YP_003116313.1. NC_013131.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 479433.Caci_5613.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACU74472 ; ACU74472 ; Caci_5613 .
    GeneIDi 8336973.
    KEGGi cai:Caci_5613.
    PATRICi 21289927. VBICatAci36872_5711.

    Phylogenomic databases

    eggNOGi COG0322.
    HOGENOMi HOG000279962.
    KOi K03703.
    OMAi AMHEVIT.
    OrthoDBi EOG6K13R9.

    Enzyme and pathway databases

    BioCyci CACI479433:GI6Z-5649-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1440.10. 1 hit.
    4.10.860.10. 1 hit.
    HAMAPi MF_00203. UvrC.
    InterProi IPR027299. GIY-YIG_dom.
    IPR000305. GIY-YIG_SF.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR010994. RuvA_2-like.
    IPR001943. UVR_dom.
    IPR004791. UvrC.
    IPR001162. UvrC_homol_region.
    [Graphical view ]
    Pfami PF01541. GIY-YIG. 1 hit.
    PF02151. UVR. 1 hit.
    PF08459. UvrC_HhH_N. 1 hit.
    [Graphical view ]
    SMARTi SM00465. GIYc. 1 hit.
    SM00278. HhH1. 2 hits.
    [Graphical view ]
    SUPFAMi SSF46600. SSF46600. 1 hit.
    SSF47781. SSF47781. 1 hit.
    SSF82771. SSF82771. 1 hit.
    TIGRFAMsi TIGR00194. uvrC. 1 hit.
    PROSITEi PS50164. GIY_YIG. 1 hit.
    PS50151. UVR. 1 hit.
    PS50165. UVRC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897Imported.

    Entry informationi

    Entry nameiC7QAZ9_CATAD
    AccessioniPrimary (citable) accession number: C7QAZ9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 13, 2009
    Last sequence update: October 13, 2009
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3