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Protein

UvrABC system protein C

Gene

uvrC

Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nucleaseUniRule annotationSAAS annotation
Biological processDNA damage, DNA excisionUniRule annotationSAAS annotation, DNA repair, SOS responseUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciCACI479433:G1GFP-5616-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotationSAAS annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:Caci_5613Imported
OrganismiCatenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)Imported
Taxonomic identifieri479433 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCatenulisporalesCatenulisporaceaeCatenulispora
Proteomesi
  • UP000000851 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi479433.Caci_5613

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 95GIY-YIGInterPro annotationAdd BLAST80
Domaini208 – 243UVRInterPro annotationAdd BLAST36
Domaini259 – 515UVRCInterPro annotationAdd BLAST257

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili211 – 247Sequence analysisAdd BLAST37

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CII Bacteria
COG0322 LUCA
HOGENOMiHOG000279962
KOiK03703
OMAiLFPIRQC
OrthoDBiPOG091H01BS

Family and domain databases

Gene3Di3.30.420.340, 1 hit
3.40.1440.10, 1 hit
HAMAPiMF_00203 UvrC, 1 hit
InterProiView protein in InterPro
IPR000305 GIY-YIG_endonuc
IPR035901 GIY-YIG_endonuc_sf
IPR003583 Hlx-hairpin-Hlx_DNA-bd_motif
IPR010994 RuvA_2-like
IPR001943 UVR_dom
IPR036876 UVR_dom_sf
IPR004791 UvrC
IPR001162 UvrC_homol_region
IPR038476 UvrC_homol_region_sf
PfamiView protein in Pfam
PF01541 GIY-YIG, 1 hit
PF02151 UVR, 1 hit
PF08459 UvrC_HhH_N, 1 hit
SMARTiView protein in SMART
SM00465 GIYc, 1 hit
SM00278 HhH1, 2 hits
SUPFAMiSSF46600 SSF46600, 1 hit
SSF47781 SSF47781, 1 hit
SSF82771 SSF82771, 1 hit
TIGRFAMsiTIGR00194 uvrC, 1 hit
PROSITEiView protein in PROSITE
PS50164 GIY_YIG, 1 hit
PS50151 UVR, 1 hit
PS50165 UVRC, 1 hit

Sequencei

Sequence statusi: Complete.

C7QAZ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADPATYRPK PGEIPTSPGV YKFRDPHSRV IYVGKAKNLR SRLTSYFQDL
60 70 80 90 100
ANLHVRTQTM VTTAASVEWT TVATEVEALQ LEYTWIKQFE PRFNVKYRDD
110 120 130 140 150
KSYPSLAVTV GEEFPRAQVM RGPKRPGVRY FGPYSHAWAI RETLDSLLRV
160 170 180 190 200
FPIRTCSSGV FKRAAQTGRP CLLGYIGKCS APCVGRVSAE EHREIVDDFV
210 220 230 240 250
SFMAGRTDRY IRGLEEEMKE AAKELEFEKA ARLRDDLQAL KQSLEKNAVV
260 270 280 290 300
LGDGTDADVI ALSEDPLEAA VQVFHVRGGR IRGQRGWVVD RVEDVDTAGL
310 320 330 340 350
VEHFMQQLYG SEQGEPGIDT ETVPREILVP ELPGSVEAIT EWLSARRGAK
360 370 380 390 400
VEVRIPKRGD KAALMETVAQ NAKQALALHK TRRASDLTTR SVALQELADA
410 420 430 440 450
IGMDQAPLRI ECYDISHLQG TNVVASMVVF EDGLPRKSEY RRFTIKGSDE
460 470 480 490 500
NGATNDDVRN MHEVITRRFK AFLKEQEEEK LIDATIGDRK KFSYPPQLVV
510 520 530 540 550
VDGGQPQVAA AARALADLEI SDVTLVGLAK RLEEVWLPDE DDPVLLPRSS
560 570 580 590 600
EGLYMLQRVR DEAHRFGIAF HRQKRSKSMV ASALDDVPGL GEVRRKALLA
610 620 630 640 650
HFGTLRKLRA AQVAEIAEVP GIGPATARQI HSALAELPVS RAVNAATGEI
660
LDGGESRNGP DEE
Length:663
Mass (Da):73,646
Last modified:October 13, 2009 - v1
Checksum:iA00C377ADDCB83A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001700 Genomic DNA Translation: ACU74472.1
RefSeqiWP_015794201.1, NC_013131.1

Genome annotation databases

EnsemblBacteriaiACU74472; ACU74472; Caci_5613
KEGGicai:Caci_5613

Similar proteinsi

Entry informationi

Entry nameiC7QAZ9_CATAD
AccessioniPrimary (citable) accession number: C7QAZ9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: March 28, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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