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C7Q8T3 (C7Q8T3_CATAD) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable DNA ligase HAMAP-Rule MF_00407

EC=6.5.1.1 HAMAP-Rule MF_00407
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP] HAMAP-Rule MF_00407
Gene names
Name:lig HAMAP-Rule MF_00407
Ordered Locus Names:Caci_1425 EMBL ACU70348.1
OrganismCatenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) [Complete proteome] [HAMAP] EMBL ACU70348.1
Taxonomic identifier479433 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCatenulisporineaeCatenulisporaceaeCatenulispora

Protein attributes

Sequence length527 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). HAMAP-Rule MF_00407

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. HAMAP-Rule MF_00407 RuleBase RU004196

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2261N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2241ATP By similarity HAMAP-Rule MF_00407
Binding site2311ATP By similarity HAMAP-Rule MF_00407
Binding site2461ATP By similarity HAMAP-Rule MF_00407
Binding site2751ATP By similarity HAMAP-Rule MF_00407
Binding site3151ATP By similarity HAMAP-Rule MF_00407
Binding site3871ATP By similarity HAMAP-Rule MF_00407
Binding site3931ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
C7Q8T3 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: D45A9D33F9221C3B

FASTA52756,425
        10         20         30         40         50         60 
MRLHDVATTS AAVAETSARS AKIALLAERL RTATPEEVAV AVHYLSGELP QRQIGVGWAT 

        70         80         90        100        110        120 
LRELPAPADD SGGSNSSDGS DGSASTAGLE VAEVDRILEE IGKTTGAGSQ ARRRDLLTAL 

       130        140        150        160        170        180 
FARATAEEQA FLRRLLTGEL RQGALDGVMA DAVAKAADVP AAEVRRAAMF GGDLAAAAQT 

       190        200        210        220        230        240 
ALRAGVPGLR EVGLVVGRPI QPMLAGTAED VPTALAKASP AALEWKLDGI RVQIHRDGDR 

       250        260        270        280        290        300 
VQVFTRSLDD ITERLPEAVA LARSLQVTSA VLDGEALALA ADGRPRPFQE TASRTGSRRD 

       310        320        330        340        350        360 
VERMREQIPL TVFLFDLLHL DGRDLVDLPS RERSDLLASI APPAAVAPRL VTDDADAAEA 

       370        380        390        400        410        420 
FAKDALDRGH EGVVVKSLDA LYSAGRRGSG WLKVKPVHTL DLVVLAAEWG HGRRRGWLSN 

       430        440        450        460        470        480 
LHLAARDPET GGFVMLGKTF KGMTDELLTW QTERLRALQT SADDFAVHVR PELVVEVAFD 

       490        500        510        520 
GVQRSSRYPG GVTLRFARVV RYREDKRAED ADTIDAVRAI GQGQEQA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001700 Genomic DNA. Translation: ACU70348.1.
RefSeqYP_003112189.1. NC_013131.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING479433.Caci_1425.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACU70348; ACU70348; Caci_1425.
GeneID8332764.
KEGGcai:Caci_1425.
PATRIC21281360. VBICatAci36872_1442.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1793.
HOGENOMHOG000036008.
KOK01971.
OMAGRPRPFQ.
OrthoDBEOG6Q8HXT.
ProtClustDBPRK03180.

Enzyme and pathway databases

BioCycCACI479433:GI6Z-1441-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 2 hits.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC7Q8T3_CATAD
AccessionPrimary (citable) accession number: C7Q8T3
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: February 19, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)