C7P8V9 (C7P8V9_METFA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphatidylserine decarboxylase proenzyme HAMAP MF_00664
EC=4.1.1.65 HAMAP MF_00664

Gene names

Name:	psd HAMAP MF_00664
Ordered Locus Names:	Mefer_1182

Organism

Methanocaldococcus fervens (strain DSM 4213 / JCM 157852 / AG86) (Methanococcus fervens) [Complete proteome] [HAMAP]

Taxonomic identifier

573064 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	214 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664
Cofactor	Pyruvoyl group By similarity. HAMAP MF_00664
Pathway	Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664
Sequence similarities	Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily. HAMAP MF_00664

Ontologies

Keywords
Biological process	Phospholipid biosynthesis HAMAP MF_00664
Ligand	Pyruvate HAMAP MF_00664
Molecular function	Decarboxylase HAMAP MF_00664 Lyase
PTM	Zymogen HAMAP MF_00664
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phosphatidylethanolamine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cofactor binding Inferred from electronic annotation. Source: InterPro phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Site	181 – 182	2	Cleavage (non-hydrolytic) By similarity HAMAP MF_00664
Amino acid modifications
	Modified residue	182	1	Pyruvic acid (Ser) By similarity HAMAP MF_00664

Sequences

	Sequence		Length	Mass (Da)
	C7P8V9 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: 5BC2415136805F52	FASTA	214	23,974
	10 20 30 40 50 60 MKNANGVKSM ANKYKKFFAV TVCSLLLFTV YFYRDPDRDV IKEDNIILSP ADGTVEYIKF 70 80 90 100 110 120 YENGEAEVFK DGNSYILNVS KYFPYGCYVV GIFMSPLDVH VNRAPISGEV VYIEHVDGGY 130 140 150 160 170 180 YPAFLKDVEK VNERNIVIIK NGSDYVGVVQ IAGFVARRCS LNLKEGDYVE MGQRIGKIKL 190 200 210 GSQTAVIIPS NYNVTVKEGE RVYAGQTIIA VRAN

References

[1]

"Complete sequence of chromosome of Methanocaldococcus fervens AG86." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Lupa-Sieprawska M., Whitman W.B. Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 4213 / JCM 157852 / AG86.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001696 Genomic DNA. Translation: ACV24991.1.
RefSeq	YP_003128491.1. NC_013156.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C7P8V9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8365884.
GenomeReviews	Gene locus Mefer_1182 in contig CP001696_GR.
KEGG	mfe:Mefer_1182.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NERVVWH.
ProtClustDB	PRK05305.
Family and domain databases
HAMAP	MF_00664. PS_decarb_type3. [Tree]
InterPro	IPR003817. PS_Dcarbxylase. IPR004428. PtdSer_deCO2ase-related. [Graphical view]
KO	K01613.
Pfam	PF02666. PS_Dcarbxylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00164. PS_decarb_rel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C7P8V9_METFA

Accession

Primary (citable) accession number: C7P8V9

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	November 16, 2011
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)