ID   C7P8Q2_METFA            Unreviewed;       186 AA.
AC   C7P8Q2;
DT   13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT   13-OCT-2009, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=CoB/CoM heterodisulfide reductase, subunit C {ECO:0000313|EMBL:ACV24934.1};
DE            EC=1.8.98.1 {ECO:0000313|EMBL:ACV24934.1};
GN   OrderedLocusNames=Mefer_1124 {ECO:0000313|EMBL:ACV24934.1};
OS   Methanocaldococcus fervens (strain DSM 4213 / JCM 15782 / AG86)
OS   (Methanococcus fervens).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=573064 {ECO:0000313|EMBL:ACV24934.1, ECO:0000313|Proteomes:UP000001495};
RN   [1] {ECO:0000313|EMBL:ACV24934.1, ECO:0000313|Proteomes:UP000001495}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 4213 / JCM 15782 / AG86
RC   {ECO:0000313|Proteomes:UP000001495};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA   Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G.,
RA   Lupa-Sieprawska M., Whitman W.B.;
RT   "Complete sequence of chromosome of Methanocaldococcus fervens AG86.";
RL   Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Cofactor metabolism; coenzyme M-coenzyme B heterodisulfide
CC       reduction; coenzyme B and coenzyme M from coenzyme M-coenzyme B
CC       heterodisulfide: step 1/1. {ECO:0000256|ARBA:ARBA00004808}.
CC   -!- SIMILARITY: Belongs to the HdrC family.
CC       {ECO:0000256|ARBA:ARBA00007097}.
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DR   EMBL; CP001696; ACV24934.1; -; Genomic_DNA.
DR   RefSeq; WP_015791670.1; NC_013156.1.
DR   AlphaFoldDB; C7P8Q2; -.
DR   STRING; 573064.Mefer_1124; -.
DR   GeneID; 8365825; -.
DR   KEGG; mfe:Mefer_1124; -.
DR   eggNOG; arCOG00964; Archaea.
DR   HOGENOM; CLU_121273_0_0_2; -.
DR   OrthoDB; 144910at2157; -.
DR   UniPathway; UPA00647; UER00700.
DR   Proteomes; UP000001495; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051912; F:CoB--CoM heterodisulfide reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0015948; P:methanogenesis; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR017680; CoB/CoM_hetero-S_Rdtase_csu.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   NCBIfam; TIGR03290; CoB_CoM_SS_C; 1.
DR   PANTHER; PTHR32479; GLYCOLATE OXIDASE IRON-SULFUR SUBUNIT; 1.
DR   PANTHER; PTHR32479:SF17; GLYCOLATE OXIDASE IRON-SULFUR SUBUNIT; 1.
DR   Pfam; PF13183; Fer4_8; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Methanogenesis {ECO:0000256|ARBA:ARBA00022994};
KW   Oxidoreductase {ECO:0000313|EMBL:ACV24934.1}.
FT   DOMAIN          26..56
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   186 AA;  21039 MW;  986DF55A019E1731 CRC64;
     MAVINLDKTN KKFVDEVVEA GKLVLGEDVV KSVKACYQCG TCTGSCPSGR RTAYRTRKVL
     RKVLLGLDDV LDSDDIWYCT TCYTCYERCP RDVKITEIIK TLRNIAAQKG NMALAHRKTA
     SYVLRFGHAV PANKEVVELR GKLGLPAKSP TAQFSEKDLE EVRTLVKELE FDKLIDFDWK
     KMDLKE
//