Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

C7P8M1 (C7P8M1_METFA) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length192 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O. HAMAP-Rule MF_00076

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9. HAMAP-Rule MF_00076

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00076.

Sequence similarities

Belongs to the imidazoleglycerol-phosphate dehydratase family. HAMAP-Rule MF_00076

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Histidine biosynthesis HAMAP-Rule MF_00076
   Cellular componentCytoplasm HAMAP-Rule MF_00076
   Molecular functionLyase HAMAP-Rule MF_00076 EMBL ACV24903.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processhistidine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionimidazoleglycerol-phosphate dehydratase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
C7P8M1 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 2F868E62BA9A6683

FASTA19221,609
        10         20         30         40         50         60 
MRVFEVMRET KETNIYLKIN IDGTGKYKID TGIPFFDHLL SSFAKHGCFD LIVKARGDLE 

        70         80         90        100        110        120 
VDDHHTVEDV GICLGLALNQ IERKNIFRFG WAIIPMDDAR ATVAIDLGGR SYCVGNYKPN 

       130        140        150        160        170        180 
REFVGDLATE NINHFFESVA SYGMLNIHYD VIGKNEHHKA EALFKAFGVA LDLATKIDER 

       190 
KGIISTKGEI KL 

« Hide

References

[1]"Complete sequence of chromosome of Methanocaldococcus fervens AG86."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Lupa-Sieprawska M., Whitman W.B.
Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 4213 / JCM 157852 / AG86.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001696 Genomic DNA. Translation: ACV24903.1.
RefSeqYP_003128403.1. NC_013156.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING573064.Mefer_1092.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACV24903; ACV24903; Mefer_1092.
GeneID8365793.
KEGGmfe:Mefer_1092.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0131.
HOGENOMHOG000228064.
KOK01693.
OMAQSISCAS.
ProtClustDBPRK00951.

Enzyme and pathway databases

BioCycMFER573064:GHUI-1132-MONOMER.
UniPathwayUPA00031; UER00011.

Family and domain databases

HAMAPMF_00076. HisB.
InterProIPR000807. ImidazoleglycerolP_deHydtase.
IPR020565. ImidazoleglycerP_deHydtase_CS.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERPTHR23133:SF2. PTHR23133:SF2. 1 hit.
PfamPF00475. IGPD. 1 hit.
[Graphical view]
SUPFAMSSF54211. SSF54211. 2 hits.
PROSITEPS00954. IGP_DEHYDRATASE_1. 1 hit.
PS00955. IGP_DEHYDRATASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC7P8M1_METFA
AccessionPrimary (citable) accession number: C7P8M1
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: February 19, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)