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C7P607 (RIBL_METFA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
FAD synthase

EC=2.7.7.2
Alternative name(s):
FMN adenylyltransferase
Flavin adenine dinucleotide synthase
Gene names
Name:ribL
Ordered Locus Names:Mefer_0147
OrganismMethanocaldococcus fervens (strain DSM 4213 / JCM 157852 / AG86) (Methanococcus fervens) [Complete proteome] [HAMAP]
Taxonomic identifier573064 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length150 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme By similarity. HAMAP-Rule MF_02115

Catalytic activity

ATP + FMN = diphosphate + FAD. HAMAP-Rule MF_02115

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_02115

Pathway

Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1. HAMAP-Rule MF_02115

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_02115

Sequence similarities

Belongs to the archaeal FAD synthase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 150150FAD synthase HAMAP-Rule MF_02115
PRO_0000406247

Regions

Nucleotide binding11 – 122ATP By similarity
Nucleotide binding16 – 194ATP By similarity
Nucleotide binding94 – 974ATP By similarity

Sites

Binding site1241ATP; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
C7P607 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 8BD35C0D4B039447

FASTA15017,249
        10         20         30         40         50         60 
MVKKRVVTAG TFDILHPGHY EVLKFAKSLG DELIVIVARD ETVKKIKGRK PIIPEEQRRE 

        70         80         90        100        110        120 
MVEALKPVDK AILGSLKNKL EPILELKPDV IVLGPDQTTF DEETLKEELA KYGLHPEIVR 

       130        140        150 
FKGYKKCPFH SSFDIVKEII RRFCNKEIKI 

« Hide

References

[1]"Complete sequence of chromosome of Methanocaldococcus fervens AG86."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Lupa-Sieprawska M., Whitman W.B.
Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 4213 / JCM 157852 / AG86.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001696 Genomic DNA. Translation: ACV23989.1.
RefSeqYP_003127489.1. NC_013156.1.

3D structure databases

ProteinModelPortalC7P607.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING573064.Mefer_0147.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACV23989; ACV23989; Mefer_0147.
GeneID8364809.
KEGGmfe:Mefer_0147.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0615.
HOGENOMHOG000284153.
KOK14656.
OMAKKCPFHS.
ProtClustDBCLSK876487.

Enzyme and pathway databases

BioCycMFER573064:GHUI-147-MONOMER.
UniPathwayUPA00277; UER00407.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_02115. FAD_synth_arch.
InterProIPR004821. Cyt_trans-like.
IPR024902. FAD_synth_RibL.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsTIGR00125. cyt_tran_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRIBL_METFA
AccessionPrimary (citable) accession number: C7P607
Entry history
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: October 13, 2009
Last modified: February 19, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways