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C7P5E3

- C7P5E3_METFA

UniProt

C7P5E3 - C7P5E3_METFA

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Protein

Ribose-5-phosphate isomerase A

Gene

rpiA

Organism
Methanocaldococcus fervens (strain DSM 4213 / JCM 157852 / AG86) (Methanococcus fervens)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.UniRule annotation

Catalytic activityi

D-ribose 5-phosphate = D-ribulose 5-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei106 – 1061Proton acceptorUniRule annotation
Binding sitei124 – 1241SubstrateUniRule annotation

GO - Molecular functioni

  1. ribose-5-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pentose-phosphate shunt, non-oxidative branch Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationImported

Enzyme and pathway databases

BioCyciMFER573064:GHUI-1563-MONOMER.
UniPathwayiUPA00115; UER00412.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribose-5-phosphate isomerase AUniRule annotation (EC:5.3.1.6UniRule annotation)
Alternative name(s):
Phosphoriboisomerase AUniRule annotation
Gene namesi
Name:rpiAUniRule annotation
Ordered Locus Names:Mefer_1518Imported
OrganismiMethanocaldococcus fervens (strain DSM 4213 / JCM 157852 / AG86) (Methanococcus fervens)Imported
Taxonomic identifieri573064 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000001495: Chromosome

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi573064.Mefer_1518.

Structurei

3D structure databases

ProteinModelPortaliC7P5E3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni28 – 314Substrate bindingUniRule annotation
Regioni83 – 864Substrate bindingUniRule annotation
Regioni97 – 1004Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the ribose 5-phosphate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0120.
HOGENOMiHOG000276369.
KOiK01807.
OMAiMDQLEMK.

Family and domain databases

HAMAPiMF_00170. Rib_5P_isom_A.
InterProiIPR004788. Ribose5P_isomerase_typA.
IPR020672. Ribose5P_isomerase_typA_subgr.
[Graphical view]
PANTHERiPTHR11934. PTHR11934. 1 hit.
PfamiPF06026. Rib_5-P_isom_A. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00021. rpiA. 1 hit.

Sequencei

Sequence statusi: Complete.

C7P5E3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSNEDLKLKV AKEAVKLVKD GMVVGLGTGS TAALFIRELG NRIQGEELTV
60 70 80 90 100
FGIPTSFEAK MLAMQYGIPL VSLDEYDVDI AFDGADEVEE KTLFLIKGGG
110 120 130 140 150
GCHTQEKIVD YNANEFVVLV DESKLVKNLG EKFPIPVEVI PSAYRVVIRA
160 170 180 190 200
LSEMGGEAVI RLGERKRGPV ITDNGNMIID VFMKVDDAVE LEKEINNIPG
210 220
VVENGIFTKV DKVLVGTKKG VKTLKK
Length:226
Mass (Da):24,643
Last modified:October 13, 2009 - v1
Checksum:i57F870173ABCE4AB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001696 Genomic DNA. Translation: ACV25321.1.
RefSeqiYP_003128821.1. NC_013156.1.

Genome annotation databases

EnsemblBacteriaiACV25321; ACV25321; Mefer_1518.
GeneIDi8366224.
KEGGimfe:Mefer_1518.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001696 Genomic DNA. Translation: ACV25321.1 .
RefSeqi YP_003128821.1. NC_013156.1.

3D structure databases

ProteinModelPortali C7P5E3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 573064.Mefer_1518.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACV25321 ; ACV25321 ; Mefer_1518 .
GeneIDi 8366224.
KEGGi mfe:Mefer_1518.

Phylogenomic databases

eggNOGi COG0120.
HOGENOMi HOG000276369.
KOi K01807.
OMAi MDQLEMK.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00412 .
BioCyci MFER573064:GHUI-1563-MONOMER.

Family and domain databases

HAMAPi MF_00170. Rib_5P_isom_A.
InterProi IPR004788. Ribose5P_isomerase_typA.
IPR020672. Ribose5P_isomerase_typA_subgr.
[Graphical view ]
PANTHERi PTHR11934. PTHR11934. 1 hit.
Pfami PF06026. Rib_5-P_isom_A. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00021. rpiA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Methanocaldococcus fervens AG86."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Lupa-Sieprawska M., Whitman W.B.
    Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 4213 / JCM 157852 / AG86Imported.

Entry informationi

Entry nameiC7P5E3_METFA
AccessioniPrimary (citable) accession number: C7P5E3
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: October 1, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3