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C7P5E3 (C7P5E3_METFA) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Ribose-5-phosphate isomerase A HAMAP-Rule MF_00170

EC=5.3.1.6 HAMAP-Rule MF_00170
Alternative name(s):
Phosphoriboisomerase A HAMAP-Rule MF_00170
Gene names
Name:rpiA HAMAP-Rule MF_00170
Ordered Locus Names:Mefer_1518 EMBL ACV25321.1
OrganismMethanocaldococcus fervens (strain DSM 4213 / JCM 157852 / AG86) (Methanococcus fervens) [Complete proteome] [HAMAP] EMBL ACV25321.1
Taxonomic identifier573064 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length226 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate By similarity. HAMAP-Rule MF_00170

Catalytic activity

D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP-Rule MF_00170

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP-Rule MF_00170

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00170

Sequence similarities

Belongs to the ribose 5-phosphate isomerase family. HAMAP-Rule MF_00170

Ontologies

Keywords
   Molecular functionIsomerase HAMAP-Rule MF_00170 EMBL ACV25321.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpentose-phosphate shunt, non-oxidative branch

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionribose-5-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region28 – 314Substrate binding By similarity HAMAP-Rule MF_00170
Region83 – 864Substrate binding By similarity HAMAP-Rule MF_00170
Region97 – 1004Substrate binding By similarity HAMAP-Rule MF_00170

Sites

Active site1061Proton acceptor By similarity HAMAP-Rule MF_00170
Binding site1241Substrate By similarity HAMAP-Rule MF_00170

Sequences

Sequence LengthMass (Da)Tools
C7P5E3 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 57F870173ABCE4AB

FASTA22624,643
        10         20         30         40         50         60 
MSNEDLKLKV AKEAVKLVKD GMVVGLGTGS TAALFIRELG NRIQGEELTV FGIPTSFEAK 

        70         80         90        100        110        120 
MLAMQYGIPL VSLDEYDVDI AFDGADEVEE KTLFLIKGGG GCHTQEKIVD YNANEFVVLV 

       130        140        150        160        170        180 
DESKLVKNLG EKFPIPVEVI PSAYRVVIRA LSEMGGEAVI RLGERKRGPV ITDNGNMIID 

       190        200        210        220 
VFMKVDDAVE LEKEINNIPG VVENGIFTKV DKVLVGTKKG VKTLKK 

« Hide

References

[1]"Complete sequence of chromosome of Methanocaldococcus fervens AG86."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Lupa-Sieprawska M., Whitman W.B.
Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 4213 / JCM 157852 / AG86.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001696 Genomic DNA. Translation: ACV25321.1.
RefSeqYP_003128821.1. NC_013156.1.

3D structure databases

ProteinModelPortalC7P5E3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING573064.Mefer_1518.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACV25321; ACV25321; Mefer_1518.
GeneID8366224.
KEGGmfe:Mefer_1518.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0120.
HOGENOMHOG000276369.
KOK01807.
OMAMDQLEMK.

Enzyme and pathway databases

BioCycMFER573064:GHUI-1563-MONOMER.
UniPathwayUPA00115; UER00412.

Family and domain databases

HAMAPMF_00170. Rib_5P_isom_A.
InterProIPR004788. Ribose5P_isomerase_typA.
IPR020672. Ribose5P_isomerase_typA_subgr.
[Graphical view]
PANTHERPTHR11934. PTHR11934. 1 hit.
PfamPF06026. Rib_5-P_isom_A. 1 hit.
[Graphical view]
TIGRFAMsTIGR00021. rpiA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC7P5E3_METFA
AccessionPrimary (citable) accession number: C7P5E3
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: June 11, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)