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C7P5E3

- C7P5E3_METFA

UniProt

C7P5E3 - C7P5E3_METFA

Protein

Ribose-5-phosphate isomerase A

Gene

rpiA

Organism
Methanocaldococcus fervens (strain DSM 4213 / JCM 157852 / AG86) (Methanococcus fervens)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (13 Oct 2009)
      Previous versions | rss
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    Functioni

    Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.UniRule annotation

    Catalytic activityi

    D-ribose 5-phosphate = D-ribulose 5-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei106 – 1061Proton acceptorUniRule annotation
    Binding sitei124 – 1241SubstrateUniRule annotation

    GO - Molecular functioni

    1. ribose-5-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. pentose-phosphate shunt, non-oxidative branch Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotationImported

    Enzyme and pathway databases

    BioCyciMFER573064:GHUI-1563-MONOMER.
    UniPathwayiUPA00115; UER00412.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribose-5-phosphate isomerase AUniRule annotation (EC:5.3.1.6UniRule annotation)
    Alternative name(s):
    Phosphoriboisomerase AUniRule annotation
    Gene namesi
    Name:rpiAUniRule annotation
    Ordered Locus Names:Mefer_1518Imported
    OrganismiMethanocaldococcus fervens (strain DSM 4213 / JCM 157852 / AG86) (Methanococcus fervens)Imported
    Taxonomic identifieri573064 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
    ProteomesiUP000001495: Chromosome

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi573064.Mefer_1518.

    Structurei

    3D structure databases

    ProteinModelPortaliC7P5E3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni28 – 314Substrate bindingUniRule annotation
    Regioni83 – 864Substrate bindingUniRule annotation
    Regioni97 – 1004Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the ribose 5-phosphate isomerase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0120.
    HOGENOMiHOG000276369.
    KOiK01807.
    OMAiMDQLEMK.

    Family and domain databases

    HAMAPiMF_00170. Rib_5P_isom_A.
    InterProiIPR004788. Ribose5P_isomerase_typA.
    IPR020672. Ribose5P_isomerase_typA_subgr.
    [Graphical view]
    PANTHERiPTHR11934. PTHR11934. 1 hit.
    PfamiPF06026. Rib_5-P_isom_A. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00021. rpiA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C7P5E3-1 [UniParc]FASTAAdd to Basket

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    MSNEDLKLKV AKEAVKLVKD GMVVGLGTGS TAALFIRELG NRIQGEELTV    50
    FGIPTSFEAK MLAMQYGIPL VSLDEYDVDI AFDGADEVEE KTLFLIKGGG 100
    GCHTQEKIVD YNANEFVVLV DESKLVKNLG EKFPIPVEVI PSAYRVVIRA 150
    LSEMGGEAVI RLGERKRGPV ITDNGNMIID VFMKVDDAVE LEKEINNIPG 200
    VVENGIFTKV DKVLVGTKKG VKTLKK 226
    Length:226
    Mass (Da):24,643
    Last modified:October 13, 2009 - v1
    Checksum:i57F870173ABCE4AB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001696 Genomic DNA. Translation: ACV25321.1.
    RefSeqiYP_003128821.1. NC_013156.1.

    Genome annotation databases

    EnsemblBacteriaiACV25321; ACV25321; Mefer_1518.
    GeneIDi8366224.
    KEGGimfe:Mefer_1518.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001696 Genomic DNA. Translation: ACV25321.1 .
    RefSeqi YP_003128821.1. NC_013156.1.

    3D structure databases

    ProteinModelPortali C7P5E3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 573064.Mefer_1518.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACV25321 ; ACV25321 ; Mefer_1518 .
    GeneIDi 8366224.
    KEGGi mfe:Mefer_1518.

    Phylogenomic databases

    eggNOGi COG0120.
    HOGENOMi HOG000276369.
    KOi K01807.
    OMAi MDQLEMK.

    Enzyme and pathway databases

    UniPathwayi UPA00115 ; UER00412 .
    BioCyci MFER573064:GHUI-1563-MONOMER.

    Family and domain databases

    HAMAPi MF_00170. Rib_5P_isom_A.
    InterProi IPR004788. Ribose5P_isomerase_typA.
    IPR020672. Ribose5P_isomerase_typA_subgr.
    [Graphical view ]
    PANTHERi PTHR11934. PTHR11934. 1 hit.
    Pfami PF06026. Rib_5-P_isom_A. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00021. rpiA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Methanocaldococcus fervens AG86."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Lupa-Sieprawska M., Whitman W.B.
      Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 4213 / JCM 157852 / AG86Imported.

    Entry informationi

    Entry nameiC7P5E3_METFA
    AccessioniPrimary (citable) accession number: C7P5E3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 13, 2009
    Last sequence update: October 13, 2009
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3