C7P5D5 (C7P5D5_METFA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402
Short name=BPG-independent PGAM HAMAP MF_01402
Short name=Phosphoglyceromutase HAMAP MF_01402
Short name=aPGAM HAMAP MF_01402
EC=5.4.2.1 HAMAP MF_01402

Gene names

Name:	apgM HAMAP MF_01402
Ordered Locus Names:	Mefer_1510

Organism

Methanocaldococcus fervens (strain DSM 4213 / JCM 157852 / AG86) (Methanococcus fervens) [Complete proteome] [HAMAP]

Taxonomic identifier

573064 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	410 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily. HAMAP MF_01402

Ontologies

Keywords
Biological process	Glycolysis HAMAP MF_01402
Ligand	Pyruvate EMBL ACV25313.1
Molecular function	Isomerase HAMAP MF_01402 EMBL ACV25313.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C7P5D5 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: 84075B5F0BA6B5EC	FASTA	410	45,266
	10 20 30 40 50 60 MKEKCVIFVI DGLGDRPNEK GLTPLKEAKT PTMDRIAKEG ICGLMNAIDI GVRPGSDTAH 70 80 90 100 110 120 LAILGYNPYE VYTGRGPLEA FGVGLDLKEG DVAFRCNFAT VDENFVVLDR RAGRISPEEA 130 140 150 160 170 180 EELEKEIDGL EIDGVKVIFK SSRGYRGVLV LRGEGLSCRV TDGDPHEEGV KVDEIKPLDD 190 200 210 220 230 240 SEEAKRTAEI LNKLLKIVYE KLDKHPINEE RRKKGLPPAN IILPRGAGVV PKIEKFSEKY 250 260 270 280 290 300 NMKGACICGT GLIKGIAVMV GLDVIEVEGA TGTPKTNFMG KAKALVEALK EYDFVLVNVK 310 320 330 340 350 360 GADEASHDGK YELKKEVLEK IDEMLSYVFE HIKKDEVYFV LTGDHSTPIE MKDHSADPIP 370 380 390 400 410 IVIWGKSVRV DDVTEFNEFA CAKGALHWIK GEHIMKILLD LTGRNEKFGA

References

[1]

"Complete sequence of chromosome of Methanocaldococcus fervens AG86." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Lupa-Sieprawska M., Whitman W.B. Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 4213 / JCM 157852 / AG86.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001696 Genomic DNA. Translation: ACV25313.1.
RefSeq	YP_003128813.1. NC_013156.1.
3D structure databases
ProteinModelPortal	C7P5D5.
ModBase	Search...
Protein-protein interaction databases
STRING	C7P5D5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8366216.
GenomeReviews	Gene locus Mefer_1510 in contig CP001696_GR.
KEGG	mfe:Mefer_1510.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	DIAFRCN.
ProtClustDB	PRK04024.
Family and domain databases
HAMAP	MF_01402_A. ApgM_A. [Tree]
InterPro	IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR023665. ApgAM. IPR004456. BisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Gene3D	G3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KO	K15635.
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
SUPFAM	SSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMs	TIGR00306. ApgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C7P5D5_METFA

Accession

Primary (citable) accession number: C7P5D5

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	January 25, 2012
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)