C7P3G7 (C7P3G7_HALMD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Deoxyribose-phosphate aldolase HAMAP MF_00114
Short name=DERA HAMAP MF_00114
EC=4.1.2.4 HAMAP MF_00114

Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase HAMAP MF_00114
Phosphodeoxyriboaldolase HAMAP MF_00114

Gene names

Name:	deoC HAMAP MF_00114
Ordered Locus Names:	Hmuk_1524

Organism

Halomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541) (Haloarcula mukohataei) [Complete proteome] [HAMAP]

Taxonomic identifier

485914 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halomicrobium

Protein attributes

Sequence length	215 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP MF_00114
Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114
Subcellular location	Cytoplasm By similarity HAMAP MF_00114.
Sequence similarities	Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. HAMAP MF_00114

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00114
Ligand	Schiff base HAMAP MF_00114
Molecular function	Lyase HAMAP MF_00114 EMBL ACV47639.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	147	1	Schiff-base intermediate with acetaldehyde By similarity HAMAP MF_00114
	Active site	172	1	By similarity HAMAP MF_00114

Sequences

	Sequence		Length	Mass (Da)
	C7P3G7 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: B8ECEB316F4C332D	FASTA	215	22,346
	10 20 30 40 50 60 MDTVPERIEH TVLGPTTRWA DVQTVLDEAA QHGLRACIPP CYVERADEYA DVPLSTVVNF 70 80 90 100 110 120 PHGQGATDAV AAEATEAWDD GADEIDVVCN VGQLKAGADA AVEETISEVV AAVPIPVKVI 130 140 150 160 170 180 VEAPLLTDGE KHRAGEIVAE AGAEFCKTAT GFSDGGATVA DVELLSQYRP VKASGGVGSW 190 200 210 ERAKAMFDAG AERIGASSGV TIAEEWRAAE GGEDA

References

[1]

"Complete genome sequence of Halomicrobium mukohataei type strain (arg-2)." Tindall B.J., Schneider S., Lapidus A., Copeland A., Glavina Del Rio T., Nolan M., Lucas S., Chen F., Tice H., Cheng J.F., Saunders E., Bruce D., Goodwin L., Pitluck S., Mikhailova N., Pati A., Mavromatis K., Ivanova N. , Chen A., Palaniappan K., Chain P., Land M., Hauser L., Chang Y.J., Jeffries C.D., Brettin T., Han C., Rohde M., Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C., Detter J.C. Stand. Genomic Sci. 1:270-277(2009) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001688 Genomic DNA. Translation: ACV47639.1.
RefSeq	YP_003177346.1. NC_013202.1.
3D structure databases
ProteinModelPortal	C7P3G7.
ModBase	Search...
Protein-protein interaction databases
STRING	C7P3G7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8411045.
GenomeReviews	Gene locus Hmuk_1524 in contig CP001688_GR.
KEGG	hmu:Hmuk_1524.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	IDHTNLK.
ProtClustDB	CLSK511544.
Family and domain databases
HAMAP	MF_00114. DeoC_type1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. IPR022979. Deoxyribose_phosphate_aldo_1. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01619.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. DeoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C7P3G7_HALMD

Accession

Primary (citable) accession number: C7P3G7

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	November 16, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)