C7P059 (C7P059_HALMD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase RuleBase RU004370
EC=6.3.3.1 RuleBase RU004370

Gene names

Ordered Locus Names:

Hmuk_2746

Organism

Halomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541) (Haloarcula mukohataei) [Complete proteome] [HAMAP]

Taxonomic identifier

485914 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halomicrobium

Protein attributes

Sequence length	329 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. RuleBase RU004370
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. RuleBase RU004371
Sequence similarities	Belongs to the AIR synthase family. RuleBase RU004370

Ontologies

Keywords
Molecular function	Ligase RuleBase RU004370 EMBL ACV48851.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	phosphoribosylformylglycinamidine cyclo-ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C7P059 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: 15F8F054BE37C994	FASTA	329	34,333
	10 20 30 40 50 60 MTDDSDDEEG LTYADSGVDI DASEAATAAL IGAAGEFEGD YAGLVDIGDQ YLALATDGVG 70 80 90 100 110 120 TKLLVAEAID DYSTIGIDCI AMNVNDLVAT GVEPVAFVDY LAVEEPDDEE SEQIGAGLRE 130 140 150 160 170 180 GAKRADVALV GGETAVMPDV IKGLDIAGTC AGLAPKDAVF PGEAEPGDAI VGWPSAGIHS 190 200 210 220 230 240 NGLTLAREAV TANHEYTDDY PRDPEQTIAE ALLTPTRIYT DLLGPLRDAE THAAAHVTGG 250 260 270 280 290 300 GWTNLTRMGE HRYEITDPFD AQPIFEFVQS EGSVSDEEMH RTFNMGTGFV AAMPESAAET 310 320 VVEATDGRII GEVTDGEGCV AVRGLELTG

References

[1]

"Complete genome sequence of Halomicrobium mukohataei type strain (arg-2)." Tindall B.J., Schneider S., Lapidus A., Copeland A., Glavina Del Rio T., Nolan M., Lucas S., Chen F., Tice H., Cheng J.F., Saunders E., Bruce D., Goodwin L., Pitluck S., Mikhailova N., Pati A., Mavromatis K., Ivanova N. , Chen A., Palaniappan K., Chain P., Land M., Hauser L., Chang Y.J., Jeffries C.D., Brettin T., Han C., Rohde M., Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C., Detter J.C. Stand. Genomic Sci. 1:270-277(2009) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001688 Genomic DNA. Translation: ACV48851.1.
RefSeq	YP_003178558.1. NC_013202.1.
3D structure databases
ProteinModelPortal	C7P059.
ModBase	Search...
Protein-protein interaction databases
STRING	C7P059.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8412297.
GenomeReviews	Gene locus Hmuk_2746 in contig CP001688_GR.
KEGG	hmu:Hmuk_2746.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	PENIPRV.
ProtClustDB	PRK05385.
Family and domain databases
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004733. PurM_cligase. IPR016188. PurM_N-like. [Graphical view]
KO	K01933.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00878. PurM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C7P059_HALMD

Accession

Primary (citable) accession number: C7P059

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	November 16, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)