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C7NVX7 (C7NVX7_HALMD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamyl-tRNA(Gln) amidotransferase subunit A HAMAP-Rule MF_00120

Short name=Glu-ADT subunit A HAMAP-Rule MF_00120
EC=6.3.5.- HAMAP-Rule MF_00120
Gene names
Name:gatA HAMAP-Rule MF_00120
Ordered Locus Names:Hmuk_1993 EMBL ACV48106.1
OrganismHalomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541) (Haloarcula mukohataei) [Complete proteome] [HAMAP] EMBL ACV48106.1
Taxonomic identifier485914 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalomicrobium

Protein attributes

Sequence length426 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) By similarity. HAMAP-Rule MF_00120

Catalytic activity

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate. HAMAP-Rule MF_00120

Subunit structure

Heterotrimer of A, B and C subunits By similarity. HAMAP-Rule MF_00120

Sequence similarities

Belongs to the amidase family. GatA subfamily. HAMAP-Rule MF_00120

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site301Charge relay system By similarity HAMAP-Rule MF_00120
Active site1051Charge relay system By similarity HAMAP-Rule MF_00120
Active site1291Acyl-ester intermediate By similarity HAMAP-Rule MF_00120

Sequences

Sequence LengthMass (Da)Tools
C7NVX7 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 4EAC3B56B96061F4

FASTA42644,092
        10         20         30         40         50         60 
MATEYNAYIS DETIEGADEG PLAGQTVAVK DNISTKGVQT TCGSSMLAGY VPPYDATVVE 

        70         80         90        100        110        120 
RLTAAGATVP GKTNMDEFGM GTTTETSAYG PVENPAAPGH VPGGSSGGSA AVVAAGDADM 

       130        140        150        160        170        180 
ALGTDTGGSI RCPAAFCGVV GIKPTYGLVS RYGLVAYANS LEQIGPIAPT VEEAAELLEV 

       190        200        210        220        230        240 
IAGPDEHDAT TRDHEGATEG LADAADGDVD GLSIGVPTEL VDGADEAVVE TFWDAIDELE 

       250        260        270        280        290        300 
AQGASYHEVD LPSVEHAVEA YYVIAMSEAS SNLARFDGVR YGQSGGYEGN WNESFANARE 

       310        320        330        340        350        360 
DGFGEEVKRR VLLGTYALSA GYHDKYYKKA QDARAWVKQD FDSALDEADV LASPTMPIPP 

       370        380        390        400        410        420 
MEMGESLDDP LTMYLADANT TPVNLANLPA ISVPAGETDD GLPVGLQLVG PAFGEKQLIR 


AGSALA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001688 Genomic DNA. Translation: ACV48106.1.
RefSeqYP_003177813.1. NC_013202.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING485914.Hmuk_1993.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACV48106; ACV48106; Hmuk_1993.
GeneID8411522.
KEGGhmu:Hmuk_1993.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0154.
HOGENOMHOG000116699.
KOK02433.
OMARYDGVKY.
ProtClustDBPRK00012.

Family and domain databases

Gene3D3.90.1300.10. 1 hit.
HAMAPMF_00120. GatA.
InterProIPR000120. Amidase.
IPR020556. Amidase_CS.
IPR023631. Amidase_dom.
IPR004412. GatA.
[Graphical view]
PANTHERPTHR11895. PTHR11895. 1 hit.
PfamPF01425. Amidase. 1 hit.
[Graphical view]
SUPFAMSSF75304. Amidase_sig_enz. 1 hit.
TIGRFAMsTIGR00132. gatA. 1 hit.
PROSITEPS00571. AMIDASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC7NVX7_HALMD
AccessionPrimary (citable) accession number: C7NVX7
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: May 1, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)