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C7NVQ3

- C7NVQ3_HALMD

UniProt

C7NVQ3 - C7NVQ3_HALMD

Protein

Probable tRNA pseudouridine synthase D

Gene

truD

Organism
Halomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541) (Haloarcula mukohataei)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (13 Oct 2009)
      Previous versions | rss
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    Functioni

    Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

    Catalytic activityi

    tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei93 – 931NucleophileUniRule annotation

    GO - Molecular functioni

    1. pseudouridine synthase activity Source: UniProtKB-HAMAP
    2. RNA binding Source: InterPro

    GO - Biological processi

    1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotation

    Keywords - Biological processi

    tRNA processingUniRule annotation

    Enzyme and pathway databases

    BioCyciHMUK485914:GCKD-17-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
    Alternative name(s):
    tRNA pseudouridine(13) synthaseUniRule annotation
    tRNA pseudouridylate synthase DUniRule annotation
    tRNA-uridine isomerase DUniRule annotation
    Gene namesi
    Name:truDUniRule annotation
    Ordered Locus Names:Hmuk_0017Imported
    OrganismiHalomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541) (Haloarcula mukohataei)Imported
    Taxonomic identifieri485914 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalomicrobium
    ProteomesiUP000001746: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi485914.Hmuk_0017.

    Structurei

    3D structure databases

    ProteinModelPortaliC7NVQ3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini176 – 408233TRUDUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the pseudouridine synthase TruD family.UniRule annotation
    Contains 1 TRUD domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0585.
    HOGENOMiHOG000224849.
    KOiK06176.
    OMAiLRYERAM.

    Family and domain databases

    HAMAPiMF_01082. TruD.
    InterProiIPR020103. PsdUridine_synth_cat_dom.
    IPR001656. PsdUridine_synth_TruD.
    IPR020119. PsdUridine_synth_TruD_CS.
    IPR011760. PsdUridine_synth_TruD_insert.
    [Graphical view]
    PANTHERiPTHR13326. PTHR13326. 1 hit.
    PfamiPF01142. TruD. 1 hit.
    [Graphical view]
    SUPFAMiSSF55120. SSF55120. 2 hits.
    TIGRFAMsiTIGR00094. tRNA_TruD_broad. 1 hit.
    PROSITEiPS50984. TRUD. 1 hit.
    PS01268. UPF0024. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C7NVQ3-1 [UniParc]FASTAAdd to Basket

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    MRPAQPIEQA VGMRYYVSDG DGIGGRLRAS PEDFAVRELE AFEAEPADAD    50
    SGAYAHLVVR ATLHNWDTND FASALSDRLG ISRERVSWAG TKDKRAVTTQ 100
    LFSIADADAA DVPEIDGAEI DVVGRAGRPV LFGDLAGNAF EIIVREVDRP 150
    DGVDGITEQL REFAGSADAA DEPTVAVPNY FGQQRFGSKR PITHEVGLAI 200
    VRNDWEGAVM AYLGNPNERE PEATQAARAY VEETHDWEGA LERFPRALGY 250
    ERALCHSLAD ADDASPAAFR SALETLPTNL QTLFVNAAQS YLFNRVLSER 300
    LDRGLPFDRP VAGDVVCFAD SDAPDGLPLP DTDRTQRVTA GRVDTVERHC 350
    ERGRAFVTAP LVGTETELAE GEPGEIERAV LADAELEPTD FALPGEFDSS 400
    GTRRAVQVRS QIDVRRRDGD AVEFAFSLPK GSYATVLLRE YLKRDPAQL 449
    Length:449
    Mass (Da):48,978
    Last modified:October 13, 2009 - v1
    Checksum:i543E506E26DE3C6E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001688 Genomic DNA. Translation: ACV46168.1.
    RefSeqiWP_012807561.1. NC_013202.1.
    YP_003175875.1. NC_013202.1.

    Genome annotation databases

    EnsemblBacteriaiACV46168; ACV46168; Hmuk_0017.
    GeneIDi8409513.
    KEGGihmu:Hmuk_0017.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001688 Genomic DNA. Translation: ACV46168.1 .
    RefSeqi WP_012807561.1. NC_013202.1.
    YP_003175875.1. NC_013202.1.

    3D structure databases

    ProteinModelPortali C7NVQ3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 485914.Hmuk_0017.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACV46168 ; ACV46168 ; Hmuk_0017 .
    GeneIDi 8409513.
    KEGGi hmu:Hmuk_0017.

    Phylogenomic databases

    eggNOGi COG0585.
    HOGENOMi HOG000224849.
    KOi K06176.
    OMAi LRYERAM.

    Enzyme and pathway databases

    BioCyci HMUK485914:GCKD-17-MONOMER.

    Family and domain databases

    HAMAPi MF_01082. TruD.
    InterProi IPR020103. PsdUridine_synth_cat_dom.
    IPR001656. PsdUridine_synth_TruD.
    IPR020119. PsdUridine_synth_TruD_CS.
    IPR011760. PsdUridine_synth_TruD_insert.
    [Graphical view ]
    PANTHERi PTHR13326. PTHR13326. 1 hit.
    Pfami PF01142. TruD. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55120. SSF55120. 2 hits.
    TIGRFAMsi TIGR00094. tRNA_TruD_broad. 1 hit.
    PROSITEi PS50984. TRUD. 1 hit.
    PS01268. UPF0024. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541Imported.

    Entry informationi

    Entry nameiC7NVQ3_HALMD
    AccessioniPrimary (citable) accession number: C7NVQ3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 13, 2009
    Last sequence update: October 13, 2009
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3