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C7NVQ3

- C7NVQ3_HALMD

UniProt

C7NVQ3 - C7NVQ3_HALMD

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Protein
Probable tRNA pseudouridine synthase D
Gene
truD, Hmuk_0017
Organism
Halomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541) (Haloarcula mukohataei)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs By similarity.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei93 – 931Nucleophile By similarityUniRule annotation

GO - Molecular functioni

  1. RNA binding Source: InterPro
  2. pseudouridine synthase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

tRNA processingUniRule annotation

Enzyme and pathway databases

BioCyciHMUK485914:GCKD-17-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthase
tRNA pseudouridylate synthase D
tRNA-uridine isomerase D
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:Hmuk_0017Imported
OrganismiHalomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541) (Haloarcula mukohataei)Imported
Taxonomic identifieri485914 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalomicrobium
ProteomesiUP000001746: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi485914.Hmuk_0017.

Structurei

3D structure databases

ProteinModelPortaliC7NVQ3.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini176 – 408233TRUD By similarityUniRule annotation
Add
BLAST

Sequence similaritiesi

Contains 1 TRUD domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0585.
HOGENOMiHOG000224849.
KOiK06176.
OMAiLRYERAM.

Family and domain databases

HAMAPiMF_01082. TruD.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERiPTHR13326. PTHR13326. 1 hit.
PfamiPF01142. TruD. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 2 hits.
TIGRFAMsiTIGR00094. tRNA_TruD_broad. 1 hit.
PROSITEiPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C7NVQ3-1 [UniParc]FASTAAdd to Basket

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MRPAQPIEQA VGMRYYVSDG DGIGGRLRAS PEDFAVRELE AFEAEPADAD    50
SGAYAHLVVR ATLHNWDTND FASALSDRLG ISRERVSWAG TKDKRAVTTQ 100
LFSIADADAA DVPEIDGAEI DVVGRAGRPV LFGDLAGNAF EIIVREVDRP 150
DGVDGITEQL REFAGSADAA DEPTVAVPNY FGQQRFGSKR PITHEVGLAI 200
VRNDWEGAVM AYLGNPNERE PEATQAARAY VEETHDWEGA LERFPRALGY 250
ERALCHSLAD ADDASPAAFR SALETLPTNL QTLFVNAAQS YLFNRVLSER 300
LDRGLPFDRP VAGDVVCFAD SDAPDGLPLP DTDRTQRVTA GRVDTVERHC 350
ERGRAFVTAP LVGTETELAE GEPGEIERAV LADAELEPTD FALPGEFDSS 400
GTRRAVQVRS QIDVRRRDGD AVEFAFSLPK GSYATVLLRE YLKRDPAQL 449
Length:449
Mass (Da):48,978
Last modified:October 13, 2009 - v1
Checksum:i543E506E26DE3C6E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001688 Genomic DNA. Translation: ACV46168.1.
RefSeqiWP_012807561.1. NC_013202.1.
YP_003175875.1. NC_013202.1.

Genome annotation databases

EnsemblBacteriaiACV46168; ACV46168; Hmuk_0017.
GeneIDi8409513.
KEGGihmu:Hmuk_0017.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001688 Genomic DNA. Translation: ACV46168.1 .
RefSeqi WP_012807561.1. NC_013202.1.
YP_003175875.1. NC_013202.1.

3D structure databases

ProteinModelPortali C7NVQ3.
ModBasei Search...

Protein-protein interaction databases

STRINGi 485914.Hmuk_0017.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACV46168 ; ACV46168 ; Hmuk_0017 .
GeneIDi 8409513.
KEGGi hmu:Hmuk_0017.

Phylogenomic databases

eggNOGi COG0585.
HOGENOMi HOG000224849.
KOi K06176.
OMAi LRYERAM.

Enzyme and pathway databases

BioCyci HMUK485914:GCKD-17-MONOMER.

Family and domain databases

HAMAPi MF_01082. TruD.
InterProi IPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view ]
PANTHERi PTHR13326. PTHR13326. 1 hit.
Pfami PF01142. TruD. 1 hit.
[Graphical view ]
SUPFAMi SSF55120. SSF55120. 2 hits.
TIGRFAMsi TIGR00094. tRNA_TruD_broad. 1 hit.
PROSITEi PS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541.

Entry informationi

Entry nameiC7NVQ3_HALMD
AccessioniPrimary (citable) accession number: C7NVQ3
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: September 3, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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