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C7NVQ3 (C7NVQ3_HALMD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable tRNA pseudouridine synthase D HAMAP-Rule MF_01082
EC=5.4.99.27 HAMAP-Rule MF_01082
Alternative name(s):
tRNA pseudouridine(13) synthase HAMAP-Rule MF_01082
tRNA pseudouridylate synthase D HAMAP-Rule MF_01082
tRNA-uridine isomerase D HAMAP-Rule MF_01082
Gene names
Name:truD HAMAP-Rule MF_01082
Ordered Locus Names:Hmuk_0017 EMBL ACV46168.1
OrganismHalomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541) (Haloarcula mukohataei) [Complete proteome] [HAMAP] EMBL ACV46168.1
Taxonomic identifier485914 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halomicrobium ›

Protein attributes

Sequence length449 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs By similarity. HAMAP-Rule MF_01082

Catalytic activity

tRNA uridine13 = tRNA pseudouridine13. HAMAP-Rule MF_01082

Sequence similarities

Belongs to the pseudouridine synthase TruD family. HAMAP-Rule MF_01082

Contains 1 TRUD domain. HAMAP-Rule MF_01082

Ontologies

Keywords
   Biological processtRNA processing HAMAP-Rule MF_01082
   Molecular functionIsomerase HAMAP-Rule MF_01082
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA pseudouridine synthesis

Inferred from electronic annotation. Source: HAMAP

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: InterPro

pseudouridine synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain176 – 408233TRUD By similarity HAMAP-Rule MF_01082

Sites

Active site931Nucleophile By similarity HAMAP-Rule MF_01082

Sequences

Sequence LengthMass (Da)Tools
C7NVQ3 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 543E506E26DE3C6E

FASTA44948,978
        10         20         30         40         50         60 
MRPAQPIEQA VGMRYYVSDG DGIGGRLRAS PEDFAVRELE AFEAEPADAD SGAYAHLVVR 

        70         80         90        100        110        120 
ATLHNWDTND FASALSDRLG ISRERVSWAG TKDKRAVTTQ LFSIADADAA DVPEIDGAEI 

       130        140        150        160        170        180 
DVVGRAGRPV LFGDLAGNAF EIIVREVDRP DGVDGITEQL REFAGSADAA DEPTVAVPNY 

       190        200        210        220        230        240 
FGQQRFGSKR PITHEVGLAI VRNDWEGAVM AYLGNPNERE PEATQAARAY VEETHDWEGA 

       250        260        270        280        290        300 
LERFPRALGY ERALCHSLAD ADDASPAAFR SALETLPTNL QTLFVNAAQS YLFNRVLSER 

       310        320        330        340        350        360 
LDRGLPFDRP VAGDVVCFAD SDAPDGLPLP DTDRTQRVTA GRVDTVERHC ERGRAFVTAP 

       370        380        390        400        410        420 
LVGTETELAE GEPGEIERAV LADAELEPTD FALPGEFDSS GTRRAVQVRS QIDVRRRDGD 

       430        440 
AVEFAFSLPK GSYATVLLRE YLKRDPAQL

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001688 Genomic DNA. Translation: ACV46168.1.
RefSeqYP_003175875.1. NC_013202.1.

3D structure databases

ProteinModelPortalC7NVQ3.
ModBaseSearch...

Protein-protein interaction databases

STRING485914.Hmuk_0017.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACV46168; ACV46168; Hmuk_0017.
GeneID8409513.
KEGGhmu:Hmuk_0017.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0585.
HOGENOMHOG000224849.
KOK06176.
OMAWAGTKDK.
ProtClustDBPRK00984.

Family and domain databases

HAMAPMF_01082. TruD.
InterProIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERPTHR13326. PTHR13326. 1 hit.
PfamPF01142. TruD. 1 hit.
[Graphical view]
SUPFAMSSF55120. PsdUridine_synth_cat_dom. 1 hit.
TIGRFAMsTIGR00094. tRNA_TruD_broad. 1 hit.
PROSITEPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC7NVQ3_HALMD
AccessionPrimary (citable) accession number: C7NVQ3
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: May 1, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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