C7NF16 (C7NF16_KYTSD) Unreviewed, UniProtKB/TrEMBL
Last modified
May 1, 2013.
Version 31.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Malate dehydrogenase RuleBase RU004066 HAMAP-Rule MF_01517 EC=1.1.1.37 RuleBase RU004066 HAMAP-Rule MF_01517 | ||||
| Gene names |
| ||||
| Organism | Kytococcus sedentarius (strain ATCC 14392 / DSM 20547 / CCM 314 / 541) (Micrococcus sedentarius) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 478801 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Dermacoccaceae › Kytococcus › ![]() |
Protein attributes
| Sequence length | 342 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Catalyzes the reversible oxidation of malate to oxaloacetate By similarity. HAMAP-Rule MF_01517 |
| Catalytic activity | (S)-malate + NAD+ = oxaloacetate + NADH. RuleBase RU004066 HAMAP-Rule MF_01517 SAAS SAAS010945 |
| Subunit structure | Homodimer By similarity. HAMAP-Rule MF_01517 SAAS SAAS010945 |
| Sequence similarities | Belongs to the LDH/MDH superfamily. MDH type 2 family. HAMAP-Rule MF_01517 RuleBase RU000421 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Tricarboxylic acid cycle RuleBase RU000422 HAMAP-Rule MF_01517 SAAS SAAS010945 |
| Ligand | NAD RuleBase RU000422 HAMAP-Rule MF_01517 SAAS SAAS010945 |
| Molecular function | Oxidoreductase RuleBase RU004066 HAMAP-Rule MF_01517 EMBL ACV05840.1 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological_process | cellular carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro malate metabolic processInferred from electronic annotation. Source: InterPro tricarboxylic acid cycleInferred from electronic annotation. Source: HAMAP |
| Molecular_function | L-malate dehydrogenase activity Inferred from electronic annotation. Source: HAMAP nucleotide bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Regions | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Nucleotide binding | 23 – 29 | 7 | NAD By similarity HAMAP-Rule MF_01517 | ||||||
| Nucleotide binding | 141 – 143 | 3 | NAD By similarity HAMAP-Rule MF_01517 | ||||||
Sites | |||||||||
| Active site | 199 | 1 | Proton acceptor By similarity HAMAP-Rule MF_01517 | ||||||
| Binding site | 104 | 1 | Substrate By similarity HAMAP-Rule MF_01517 | ||||||
| Binding site | 110 | 1 | Substrate By similarity HAMAP-Rule MF_01517 | ||||||
| Binding site | 117 | 1 | NAD By similarity HAMAP-Rule MF_01517 | ||||||
| Binding site | 124 | 1 | NAD By similarity HAMAP-Rule MF_01517 | ||||||
| Binding site | 143 | 1 | Substrate By similarity HAMAP-Rule MF_01517 | ||||||
| Binding site | 174 | 1 | Substrate By similarity HAMAP-Rule MF_01517 | ||||||
Sequences
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References
| [1] | "Complete genome sequence of Kytococcus sedentarius type strain (541)." Sims D., Brettin T., Detter J.C., Han C., Lapidus A., Copeland A., Glavina Del Rio T., Nolan M., Chen F., Lucas S., Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S., Ovchinnikova G., Pati A., Ivanova N. Klenk H.P.Stand. Genomic Sci. 1:12-20(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 14392 / DSM 20547 / CCM 314 / 541. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP001686 Genomic DNA. Translation: ACV05840.1. |
| RefSeq | YP_003148605.1. NC_013169.1. |
3D structure databases | |
| ProteinModelPortal | C7NF16. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 478801.Ksed_07840. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | ACV05840; ACV05840; Ksed_07840. |
| GeneID | 8372293. |
| KEGG | kse:Ksed_07840. |
| PATRIC | 22191223. VBIKytSed14067_0735. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0039. |
| HOGENOM | HOG000220953. |
| KO | K00024. |
| OMA | AINDHAA. |
| ProtClustDB | PRK05442. |
Enzyme and pathway databases | |
| BioCyc | KSED478801:GI4L-780-MONOMER. |
Family and domain databases | |
| Gene3D | 3.40.50.720. 1 hit. 3.90.110.10. 1 hit. |
| HAMAP | MF_01517. Malate_dehydrog_2. |
| InterPro | IPR001557. L-lactate/malate_DH. IPR022383. Lactate/malate_DH_C. IPR001236. Lactate/malate_DH_N. IPR015955. Lactate_DH/Glyco_Ohase_4_C. IPR001252. Malate_DH_AS. IPR010945. Malate_DH_type2. IPR016040. NAD(P)-bd_dom. [Graphical view] |
| PANTHER | PTHR23382. PTHR23382. 1 hit. |
| Pfam | PF02866. Ldh_1_C. 1 hit. PF00056. Ldh_1_N. 1 hit. [Graphical view] |
| PIRSF | PIRSF000102. Lac_mal_DH. 1 hit. |
| SUPFAM | SSF56327. Lactate_DH/Glyco_hydro_4_C. 1 hit. |
| TIGRFAMs | TIGR01759. MalateDH-SF1. 1 hit. |
| PROSITE | PS00068. MDH. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | C7NF16_KYTSD | ||||||||
| Accession | Primary (citable) accession number: C7NF16 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with
