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C7N8X4 (C7N8X4_LEPBD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
tRNA (guanine-N(7)-)-methyltransferase HAMAP-Rule MF_01057
EC=2.1.1.33 HAMAP-Rule MF_01057
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase HAMAP-Rule MF_01057
tRNA(m7G46)-methyltransferase HAMAP-Rule MF_01057
Gene names
Name:trmB HAMAP-Rule MF_01057
Ordered Locus Names:Lebu_0697
OrganismLeptotrichia buccalis (strain ATCC 14201 / DSM 1135 / JCM 12969 / NCTC 10249) [Complete proteome] [HAMAP]
Taxonomic identifier523794 [NCBI]
Taxonomic lineageBacteria › Fusobacteria › Fusobacteriales › Leptotrichiaceae › Leptotrichia ›

Protein attributes

Sequence length274 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity. HAMAP-Rule MF_01057

Catalytic activity

S-adenosyl-L-methionine + guanine46 in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine46 in tRNA. HAMAP-Rule MF_01057

Pathway

tRNA modification; N(7)-methylguanine-tRNA biosynthesis. HAMAP-Rule MF_01057

Sequence similarities

Belongs to the methyltransferase superfamily. TrmB family. HAMAP-Rule MF_01057

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region251 – 2544Substrate binding By similarity HAMAP-Rule MF_01057

Sites

Binding site1041S-adenosyl-L-methionine By similarity HAMAP-Rule MF_01057
Binding site1291S-adenosyl-L-methionine By similarity HAMAP-Rule MF_01057
Binding site1781S-adenosyl-L-methionine By similarity HAMAP-Rule MF_01057
Binding site2121Substrate By similarity HAMAP-Rule MF_01057

Sequences

Sequence LengthMass (Da)Tools
C7N8X4 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: EB21AEF0F843B05D

FASTA27433,020
        10         20         30         40         50         60 
MENKIESIGK NGQKIEITEA EKEKREKIKK VNDEFKKINA EKSKIINEQE IWKYFFEKPK 

        70         80         90        100        110        120 
KNYNKYMYEM LEFPEYLMYN NKSVDKYREK WNEFFRNDND IYLEIGCGSG NFTVGNAEKF 

       130        140        150        160        170        180 
KDRNYIALEL RFKRLVLGAR KSKKRNLHNI LFVRKRGETI LDFLGVNEIS GVYINFPDPW 

       190        200        210        220        230        240 
EGEERKRVIT ESLFSKLDIV LKTDGKLFFK TDHEQYYKDV LELVDKLDNY KIIYHTSDLH 

       250        260        270 
NSEKASENIE TEFEQMFLSK HNMNIKYIEI KKIK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001685 Genomic DNA. Translation: ACV38605.1.
RefSeqYP_003163596.1. NC_013192.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING523794.Lebu_0697.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACV38605; ACV38605; Lebu_0697.
GeneID8407402.
KEGGlba:Lebu_0697.
PATRIC22400696. VBILepBuc70646_0708.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0220.
HOGENOMHOG000251689.
KOK03439.
OMAFRNDNDI.
ProtClustDBCLSK2820032.

Enzyme and pathway databases

BioCycLBUC523794:GHCR-723-MONOMER.
UniPathwayUPA00989.

Family and domain databases

HAMAPMF_01057. tRNA_methyltr_TrmB.
InterProIPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamPF02390. Methyltransf_4. 1 hit.
[Graphical view]
TIGRFAMsTIGR00091. TIGR00091. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC7N8X4_LEPBD
AccessionPrimary (citable) accession number: C7N8X4
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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