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C7N496 (C7N496_SLAHD) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length317 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain109 – 313205ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding140 – 19556ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2671Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2801Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2801Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2821Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
C7N496 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: EE234067BB86EBE7

FASTA31733,197
        10         20         30         40         50         60 
MGYSGNPSEY NVAVLCGGKS GEREVSLNSG KACAEALEAS GFEVTLLDTA EKADLKRLID 

        70         80         90        100        110        120 
EPFDVAFLAL HGRGGEDGTI QGFLETVGIP YTGSGINASS VAINKSKAKD AYAQAGLRVA 

       130        140        150        160        170        180 
ASMTISEDDI LDENLISDIV ETCGIPCVVK PTTEGSSLGM TIVRDAADIA EAIKTALAVD 

       190        200        210        220        230        240 
VEAMVEQFIS GTELTVGVIG NDDAEALPVI QIVPTEDEFY NYHAKYAAGG SRHLCPAPVS 

       250        260        270        280        290        300 
RDVTENAQEM AVAAHMVLGC RGVSRTDIIV DADDTCWVLE TNTIPGMTGT SLVPDAAKVA 

       310 
GMDFQQLCEK LIALALE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001684 Genomic DNA. Translation: ACV23832.1.
RefSeqYP_003145181.1. NC_013165.1.

3D structure databases

ProteinModelPortalC7N496.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING471855.Shel_28460.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACV23832; ACV23832; Shel_28460.
GeneID8396734.
KEGGshi:Shel_28460.
PATRIC23645290. VBISlaHel66389_2815.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
HOGENOMHOG000011592.
KOK01921.
OMARSAYGIY.
OrthoDBEOG6ND0KB.

Enzyme and pathway databases

BioCycSHEL471855:GH2I-2846-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC7N496_SLAHD
AccessionPrimary (citable) accession number: C7N496
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: June 11, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)