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C7N3H7 (C7N3H7_SLAHD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Shel_27010
OrganismSlackia heliotrinireducens (strain ATCC 29202 / DSM 20476 / NCTC 11029 / RHS 1) (Peptococcus heliotrinreducens) [Complete proteome] [HAMAP]
Taxonomic identifier471855 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Coriobacteridae › Coriobacteriales › Coriobacterineae › Coriobacteriaceae › Slackia

Protein attributes

Sequence length337 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2021Iron By similarity HAMAP MF_00323
Metal binding2841Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
C7N3H7 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 346D06D7422510A7

FASTA33738,168
        10         20         30         40         50         60 
MGKRTSMLGI IVTNTGTADA PEEEAIRRYL RQFLADRHLI NVPPIIWKPV MELFILPNRP 

        70         80         90        100        110        120 
RKTLPRYQAF WTPEGSPFML TSQEQCRIVN EKLQSRLDEP YLVKLAMRYG NPSIESALQA 

       130        140        150        160        170        180 
CKNAGCDRIV ALPLYPQWTI PCAGTVLDEF DIQYKKVFGE AGPELIKVLE YWEEPGYIEA 

       190        200        210        220        230        240 
LADSIARVWT YKPGSKLIMT YHSIPISYIT KGHDPYPHTT AETMRRVGER LGIPPEDRVL 

       250        260        270        280        290        300 
TYQSRFDSRK WLGPMLKNEA ARLGSEGVLD VCAVSPIFAT DCIETVWDID TEARKAHTEA 

       310        320        330 
ARELGIMNTK FTFVPSLGTD DAFMEVIANV VEKAARP

« Hide

References

[1]"Complete genome sequence of Slackia heliotrinireducens type strain (RHS 1T)."
Pukall R., Lapidus A., Nolan M., Copeland A., Glavina Del Rio T., Lucas S., Chen F., Tice H., Cheng J.F., Chertkov O., Bruce D., Goodwin L., Kuske C., Brettin T., Detter J.C., Han C., Pitluck S., Pati A. expand/collapse author list , Mavromatis K., Ivanova N., Ovchinnikova G., Chen A., Palaniappan K., Schneider S., Rohde M., Chain P., D'haeseleer P., Goker M., Bristow J., Eisen J.A., Markowitz V., Kyrpides N.C., Klenk H.P., Hugenholtz P.
Stand. Genomic Sci. 1:234-241(2009)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001684 Genomic DNA. Translation: ACV23700.1.
RefSeqYP_003145049.1. NC_013165.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC7N3H7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8396589.
GenomeReviewsGene locus Shel_27010 in contig CP001684_GR.
KEGGshi:Shel_27010.
PATRIC23645006. VBISlaHel66389_2682.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMATIEEIGM.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC7N3H7_SLAHD
AccessionPrimary (citable) accession number: C7N3H7
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: December 14, 2011
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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