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C7N012 (C7N012_SACVD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Argininosuccinate synthase HAMAP-Rule MF_00005
EC=6.3.4.5 HAMAP-Rule MF_00005
Alternative name(s):
Citrulline--aspartate ligase HAMAP-Rule MF_00005
Gene names
Name:argG HAMAP-Rule MF_00005
Ordered Locus Names:Svir_25570
OrganismSaccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101) [Complete proteome] [HAMAP] EMBL ACU97548.1
Taxonomic identifier471857 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharomonospora ›

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate. HAMAP-Rule MF_00005 SAAS SAAS018223

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. HAMAP-Rule MF_00005 SAAS SAAS018223

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00005 SAAS SAAS018223

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00005 SAAS SAAS018223.

Sequence similarities

Belongs to the argininosuccinate synthase family. Type 1 subfamily. HAMAP-Rule MF_00005

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding8 – 169ATP By similarity HAMAP-Rule MF_00005

Sites

Binding site871Citrulline By similarity HAMAP-Rule MF_00005
Binding site1171ATP; via amide nitrogen By similarity HAMAP-Rule MF_00005
Binding site1191Aspartate By similarity HAMAP-Rule MF_00005
Binding site1231Aspartate By similarity HAMAP-Rule MF_00005
Binding site1231Citrulline By similarity HAMAP-Rule MF_00005
Binding site1241Aspartate By similarity HAMAP-Rule MF_00005
Binding site1271Citrulline By similarity HAMAP-Rule MF_00005
Binding site1751Citrulline By similarity HAMAP-Rule MF_00005
Binding site2601Citrulline By similarity HAMAP-Rule MF_00005
Binding site2721Citrulline By similarity HAMAP-Rule MF_00005

Sequences

Sequence LengthMass (Da)Tools
C7N012 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: C9CE00DFED953A3E

FASTA40244,302
        10         20         30         40         50         60 
MTERVVLAYS GGLDTSVAIG WIAEETGAEV VAVAVDVGQG GEDMETIRKR ALECGAVEAV 

        70         80         90        100        110        120 
VSDAKDEFAE EYCLPALQAN ALYMDRYPLV SALSRPLIVK HLVRAAERYG ATTVAHGCTG 

       130        140        150        160        170        180 
KGNDQVRFEV GIGALAPDLK VIAPVRDFAW TREKAISWAE ERNLPIDVTK KSPFSIDQNV 

       190        200        210        220        230        240 
WGRAVETGVL EDLWNEPPKE VYSYTQDPTV HFQAPDEVII TFEKGVPVAI DGKKVTVLEA 

       250        260        270        280        290        300 
IQEMNQRAGA HGIGRLDMVE DRLVGIKSRE VYEAPGAIAL ITAHQELENV TVERDLARFK 

       310        320        330        340        350        360 
RQVEQRWGEL VYDGLWFSPL KDALDGFIAK AQEHVSGDIR MVLHGGTATV TGRRSDESLY 

       370        380        390        400 
DFNLATYDEG DTFDQSLAKG FVQLWGLPSK IAAKRQQNKN NN

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001683 Genomic DNA. Translation: ACU97548.1.
RefSeqYP_003134375.1. NC_013159.1.

3D structure databases

ProteinModelPortalC7N012.
ModBaseSearch...

Protein-protein interaction databases

STRING471857.Svir_25570.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACU97548; ACU97548; Svir_25570.
GeneID8387881.
KEGGsvi:Svir_25570.
PATRIC23395606. VBISacVir111818_2585.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0137.
HOGENOMHOG000230093.
KOK01940.
OMANDQFRFE.

Enzyme and pathway databases

UniPathwayUPA00068; UER00113.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPMF_00005. Arg_succ_synth_type1.
InterProIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR11587. PTHR11587. 1 hit.
PfamPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsTIGR00032. argG. 1 hit.
PROSITEPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC7N012_SACVD
AccessionPrimary (citable) accession number: C7N012
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: May 1, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info