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C7MYJ2 (C7MYJ2_SACVD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-deoxy-D-xylulose-5-phosphate synthase HAMAP MF_00315
EC=2.2.1.7 HAMAP MF_00315
Alternative name(s):
1-deoxyxylulose-5-phosphate synthase HAMAP MF_00315
Gene names
Name:dxs HAMAP MF_00315
Ordered Locus Names:Svir_24150
OrganismSaccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101) [Complete proteome] [HAMAP] EMBL ACU97411.1
Taxonomic identifier471857 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharomonospora

Protein attributes

Sequence length645 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) By similarity. HAMAP MF_00315 SAAS SAAS001017

Catalytic activity

Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. HAMAP MF_00315 SAAS SAAS001017

Cofactor

Binds 1 thiamine pyrophosphate per subunit By similarity. HAMAP MF_00315 SAAS SAAS001017

Pathway

Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1. HAMAP MF_00315 SAAS SAAS001017

Subunit structure

Homodimer By similarity. HAMAP MF_00315 SAAS SAAS001017

Sequence similarities

Belongs to the transketolase family. DXPS subfamily. HAMAP MF_00315

Sequences

Sequence LengthMass (Da)Tools
C7MYJ2 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 8876E929D341F14F

FASTA64568,532
        10         20         30         40         50         60 
MTLLESVHGP ADLKRMDHDQ LRVLAEEIRD FLVEKVCRTG GHLGPNLGVV ELTLALHRVF 

        70         80         90        100        110        120 
DSPKDALLFD VGHQSYVHKI VTGRHRDFDR LRQLGGISGY PARAESEHDI IENSHASTAL 

       130        140        150        160        170        180 
SYADGLARAY QLAGGGRHAV AIVGDGALTG GMCWEALNNI AADPERPVVI VVNDNGRSYS 

       190        200        210        220        230        240 
PTIGGFAEHL AALRLRRGYE RLLDGGKELL QNTPVVGKPL YTALHAAKAG IKDALSPQVM 

       250        260        270        280        290        300 
FSDLGLKYIG PVDGHDLPAL EKALLNAKAF GGPVIVHAVT QKGHGYPPAV NHKADQMHQT 

       310        320        330        340        350        360 
DPVDPQTGKP PVKGPSWTSV FGDELVKIGA ERQDVVAITA AMLRSTGLQK FADAFPDRCI 

       370        380        390        400        410        420 
DVGIAEQHAV TSAAGLAMGG LHPVVAVYST FLNRAFDQVL LDVALHRQPV TLVLDRAGIT 

       430        440        450        460        470        480 
GPDGPSHHGM WDLSLLGMVP GMRVAAPRDA QTLREELREA VAVSDGPTAL RFSRGSVVDS 

       490        500        510        520        530        540 
VPAVDRLGCV DVLRQANDED VLLVAVGAFG QLGLAAADRL ADQGIGVTVV DPRWVLPVPE 

       550        560        570        580        590        600 
ELVDLAASYR LVVTLEDSGR HGGFGSALAT ALRDADCDVP LRDLAVPQQF LEHGTREEVL 

       610        620        630        640 
ASIGLTAQDV ARKVTEWAAG RLGDSVQESE AAEGAAGKAV DASHD

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001683 Genomic DNA. Translation: ACU97411.1.
RefSeqYP_003134238.1. NC_013159.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC7MYJ2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8387739.
GenomeReviewsGene locus Svir_24150 in contig CP001683_GR.
KEGGsvi:Svir_24150.
PATRIC23395308. VBISacVir111818_2439.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAQYDISYM.
ProtClustDBPRK05444.

Family and domain databases

HAMAPMF_00315. DXP_synth.
[Tree]
InterProIPR001017. DH_E1.
IPR005477. Dxylulose-5-P_synthase.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR020826. Transketolase_BS.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK01662.
PfamPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00204. Dxs. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC7MYJ2_SACVD
AccessionPrimary (citable) accession number: C7MYJ2
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: December 14, 2011
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info