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Protein

Glycerol-3-phosphate dehydrogenase [NAD(P)+]

Gene

gpsA

Organism
Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H.UniRule annotation

Pathwayi: glycerophospholipid metabolism

This protein is involved in the pathway glycerophospholipid metabolism, which is part of Membrane lipid metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycerophospholipid metabolism and in Membrane lipid metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei108NAD; via amide nitrogenUniRule annotation1
Binding sitei108SubstrateUniRule annotation1
Binding sitei142NAD; via amide nitrogenUniRule annotation1
Active sitei193Proton acceptorUniRule annotation1
Binding sitei257NADUniRule annotation1
Binding sitei284NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 15NADUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationSAAS annotationImported

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesisUniRule annotation, Phospholipid metabolism

Keywords - Ligandi

NADUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00940.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(P)+]UniRule annotation (EC:1.1.1.94UniRule annotation)
Alternative name(s):
NAD(P)H-dependent glycerol-3-phosphate dehydrogenaseUniRule annotation
Gene namesi
Name:gpsAUniRule annotation
Ordered Locus Names:Svir_09130Imported
OrganismiSaccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)Imported
Taxonomic identifieri471857 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPseudonocardialesPseudonocardiaceaeSaccharomonospora
Proteomesi
  • UP000000841 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi471857.Svir_09130.

Structurei

3D structure databases

ProteinModelPortaliC7MY23.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 161NAD_Gly3P_dh_NInterPro annotationAdd BLAST156
Domaini182 – 320NAD_Gly3P_dh_CInterPro annotationAdd BLAST139

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni257 – 258Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CSF. Bacteria.
COG0240. LUCA.
HOGENOMiHOG000246853.
KOiK00057.
OMAiSAQMEMS.
OrthoDBiPOG091H060E.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPiMF_00394. NAD_Glyc3P_dehydrog. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C7MY23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVQRVTVLG AGSWGTTFAK VLADAGRDVT LWARRAEVAD EIRTQHTNSS
60 70 80 90 100
YLPGVRLPER LTATSDAATA LEAADAVVFA VPSQKLRENL AAWRDLLPAD
110 120 130 140 150
AILVSLAKGV ELGTLKRMSE VISDITGVEP GDVVVVSGPN LAKEIAQQQP
160 170 180 190 200
AAAVLACADH DRAVAIQQAS FNSYFRPYTN TDVVGCELGG ACKNVIALSC
210 220 230 240 250
GMAAGLGYGT NTMATLITRG LAEMARLGAA LGADPLTFAG LAGVGDLVAT
260 270 280 290 300
CSSPLSRNRT FGERIGRGET MEQARAAQGG QVAEGVTSCR SIRELARRLD
310 320 330
VDMPITDAMY RVCHEGVDPG TVGAELLGRR QKHEWS
Length:336
Mass (Da):35,337
Last modified:October 13, 2009 - v1
Checksum:i14A3033E7C3ECACE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001683 Genomic DNA. Translation: ACU95971.1.
RefSeqiWP_012796400.1. NC_013159.1.

Genome annotation databases

EnsemblBacteriaiACU95971; ACU95971; Svir_09130.
KEGGisvi:Svir_09130.
PATRICi23392214. VBISacVir111818_0903.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001683 Genomic DNA. Translation: ACU95971.1.
RefSeqiWP_012796400.1. NC_013159.1.

3D structure databases

ProteinModelPortaliC7MY23.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi471857.Svir_09130.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACU95971; ACU95971; Svir_09130.
KEGGisvi:Svir_09130.
PATRICi23392214. VBISacVir111818_0903.

Phylogenomic databases

eggNOGiENOG4105CSF. Bacteria.
COG0240. LUCA.
HOGENOMiHOG000246853.
KOiK00057.
OMAiSAQMEMS.
OrthoDBiPOG091H060E.

Enzyme and pathway databases

UniPathwayiUPA00940.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPiMF_00394. NAD_Glyc3P_dehydrog. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiC7MY23_SACVD
AccessioniPrimary (citable) accession number: C7MY23
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: November 30, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.