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C7MXF2 (C7MXF2_SACVD) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate--tRNA ligase HAMAP MF_00022
EC=6.1.1.17 HAMAP MF_00022
Alternative name(s):
Glutamyl-tRNA synthetase HAMAP MF_00022
Gene names
Name:gltX HAMAP MF_00022
Ordered Locus Names:Svir_09010
OrganismSaccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101) [Complete proteome] [HAMAP] EMBL ACU95961.1
Taxonomic identifier471857 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharomonospora

Protein attributes

Sequence length493 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) By similarity. HAMAP MF_00022

Catalytic activity

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu). HAMAP MF_00022

Subunit structure

Monomer By similarity. HAMAP MF_00022

Subcellular location

Cytoplasm By similarity HAMAP MF_00022.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP MF_00022

Ontologies

Keywords
   Biological processProtein biosynthesis HAMAP MF_00022
   Cellular componentCytoplasm HAMAP MF_00022
   LigandATP-binding HAMAP MF_00022
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase HAMAP MF_00022 EMBL ACU95961.1
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglutamyl-tRNA aminoacylation

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: HAMAP

glutamate-tRNA ligase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif13 – 2311"HIGH" region By similarity HAMAP MF_00022
Motif257 – 2615"KMSKS" region By similarity HAMAP MF_00022

Sites

Binding site2601ATP By similarity HAMAP MF_00022

Sequences

Sequence LengthMass (Da)Tools
C7MXF2 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 082D3B1CDCF6EF3B

FASTA49355,354
        10         20         30         40         50         60 
MSETKAVRAR FCPSPTGTPH VGLIRTALFN WAFARHHGGS LVFRIEDTDA ARDSEESYEA 

        70         80         90        100        110        120 
LLDALRWLGL DWDEGPEVGG DYGPYRQSQR GDIYNDVARK LLEAGELYEA FSTNEEVEQR 

       130        140        150        160        170        180 
RREAGQDPKL GYDNFDRDLT EEQKERYRAE GRSPVLRLRM PDEDITWHDL VRGEITFKAG 

       190        200        210        220        230        240 
TIPDPVLVRA NGQPLYTLTN PVDDALMRIT HVLRGEDLLP STPRQIALYR AMQRVGITDF 

       250        260        270        280        290        300 
TPEFGHLPYV MGDGNKKLSK RDPKSNLFNY REQGFIREGL LNYLALLGWS IADDRDVFTV 

       310        320        330        340        350        360 
DELVEAFDIT KVSANPARFD PKKAEAINGT HVRALPVEDF VRRTVPYLSA AGVLPEQPSD 

       370        380        390        400        410        420 
EQLEKFRAIA PLVQERVTVL SDAVDLVRFL FVDEETFAPE EAAAAKALGP DSEPVLRAAV 

       430        440        450        460        470        480 
DALEALDEWR TEAIEAALKE ALVEKLGLKP RKAFAPVRVA VTGRTVSPPL YESMELLGRE 

       490 
ISLGRLRRAL SGH

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001683 Genomic DNA. Translation: ACU95961.1.
RefSeqYP_003132788.1. NC_013159.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC7MXF2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8386238.
GenomeReviewsGene locus Svir_09010 in contig CP001683_GR.
KEGGsvi:Svir_09010.
PATRIC23392190. VBISacVir111818_0893.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAESIIQFV.
ProtClustDBPRK01406.

Family and domain databases

HAMAPMF_00022_B. Glu_tRNA_synth_B.
[Tree]
InterProIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR004527. Glu-tRNA-synth_Ib_bac/mito.
IPR000924. Glu/Gln-tRNA-synth_Ib.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:1.10.1160.10. Glu/Gln-tRNA-synth_Ic_a-bdl. 1 hit.
G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
G3DSA:1.10.10.350. tRNA_synt_bd. 1 hit.
KOK01885.
PANTHERPTHR10119. Glu_tRNA-synt_1c. 1 hit.
PTHR10119:SF1. PTHR10119:SF1. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF48163. tRNA-synt_bind. 1 hit.
TIGRFAMsTIGR00464. GltX_bact. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC7MXF2_SACVD
AccessionPrimary (citable) accession number: C7MXF2
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: January 25, 2012
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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