C7MUQ7 (C7MUQ7_SACVD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Adenosine deaminase HAMAP MF_00540
EC=3.5.4.4 HAMAP MF_00540

Alternative name(s):
Adenosine aminohydrolase HAMAP MF_00540

Gene names

Name:	add HAMAP MF_00540
Ordered Locus Names:	Svir_05460

Organism

Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101) [Complete proteome] [HAMAP] EMBL ACU95620.1

Taxonomic identifier

471857 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharomonospora

Protein attributes

Sequence length	363 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Adenosine + H2O = inosine + NH3. HAMAP MF_00540
Cofactor	Binds 1 zinc ion per subunit By similarity. HAMAP MF_00540
Sequence similarities	Belongs to the adenosine and AMP deaminases family. Adenosine deaminase subfamily. HAMAP MF_00540

Ontologies

Keywords
Biological process	Nucleotide metabolism HAMAP MF_00540
Ligand	Metal-binding HAMAP MF_00540 Zinc HAMAP MF_00540
Molecular function	Hydrolase HAMAP MF_00540
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine ribonucleoside monophosphate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	adenosine deaminase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	213	1	Proton donor By similarity HAMAP MF_00540
	Metal binding	21	1	Zinc; catalytic By similarity HAMAP MF_00540
	Metal binding	23	1	Zinc; catalytic By similarity HAMAP MF_00540
	Metal binding	210	1	Zinc; catalytic By similarity HAMAP MF_00540
	Metal binding	302	1	Zinc; catalytic By similarity HAMAP MF_00540
	Binding site	23	1	Substrate By similarity HAMAP MF_00540
	Binding site	25	1	Substrate By similarity HAMAP MF_00540
	Binding site	183	1	Substrate; via amide nitrogen and carbonyl oxygen By similarity HAMAP MF_00540
	Site	234	1	Important for catalytic activity By similarity HAMAP MF_00540

Sequences

	Sequence		Length	Mass (Da)
	C7MUQ7 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: CA39F214F9106C74	FASTA	363	39,986
	10 20 30 40 50 60 MSTRTVPTLQ ELRDAPKVLL HDHLDGGLRP GTVVELAEET GYDGLPTTDV GELSRWFKTA 70 80 90 100 110 120 ADSGSLESYL ETFAHTCGVM QTEEALSRVA AECVEDLADD GVVYAEVRYA PELFVERGLS 130 140 150 160 170 180 LEAVVEAVQD GFDRGRKAAA ERGRNIRVGQ LLCAMRQHAR AREVADLTVR YRDRGVVGFD 190 200 210 220 230 240 IAGPEAGYPP TRNLDAFEFL RENNAHFTIH AGEAFGLASI WEAIQHCGAE RLGHGVRIVD 250 260 270 280 290 300 DITTSEDGEV SLGRLAAYVR DRRIPLEVCP SSNVQTGAAP SIAEHPIGLL AKLRFRVTVN 310 320 330 340 350 360 TDNRLMSDCT VSSEFAALVD AFGFDWADVQ WCTINAMKSA FISFDERLDI INNIIKPWYA ERV

References

[1]

"Complete genome sequence of Saccharomonospora viridis type strain (P101)." Pati A., Sikorski J., Nolan M., Lapidus A., Copeland A., Glavina del Rio T., Lucas S., Chen F., Tice H., Pitluck S., Cheng J.-F., Chertkov O., Brettin T., Han C., Detter J.C., Kuske C., Bruce D., Goodwin L. , Chain P., D'haeseleer P., Chen A., Palaniappan K., Ivanova N., Mavromatis K., Mikhailova N., Rohde M., Tindall B.J., Goeker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.-P. Stand. Genomic Sci. 1:141-149(2009) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001683 Genomic DNA. Translation: ACU95620.1.
RefSeq	YP_003132447.1. NC_013159.1.
3D structure databases
ProteinModelPortal	C7MUQ7.
ModBase	Search...
Protein-protein interaction databases
STRING	C7MUQ7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8385884.
GenomeReviews	Gene locus Svir_05460 in contig CP001683_GR.
KEGG	svi:Svir_05460.
PATRIC	23391458. VBISacVir111818_0535.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	PYYMAMN.
ProtClustDB	PRK09358.
Family and domain databases
HAMAP	MF_00540. A_deaminase. [Tree]
InterPro	IPR001365. A/AMP_deaminase_dom. IPR006330. A_deaminase. [Graphical view]
KO	K01488.
PANTHER	PTHR11409:SF21. PTHR11409:SF21. 1 hit.
Pfam	PF00962. A_deaminase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01430. Aden_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C7MUQ7_SACVD

Accession

Primary (citable) accession number: C7MUQ7

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)