C7MP25 (C7MP25_CRYCD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Elongation factor Tu HAMAP-Rule MF_00118
Short name=EF-Tu HAMAP-Rule MF_00118

Gene names

Name:	tuf HAMAP-Rule MF_00118
Ordered Locus Names:	Ccur_09710

Organism

Cryptobacterium curtum (strain ATCC 700683 / DSM 15641 / 12-3) [Complete proteome] [HAMAP]

Taxonomic identifier

469378 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Coriobacteridae › Coriobacteriales › Coriobacterineae › Coriobacteriaceae › Cryptobacterium › Cryptobacterium curtum

Protein attributes

Sequence length	400 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118 RuleBase RU000325
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00118
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00118.
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. HAMAP-Rule MF_00118 RuleBase RU000325

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm HAMAP-Rule MF_00118
Ligand	GTP-binding HAMAP-Rule MF_00118 RuleBase RU000323 Nucleotide-binding
Molecular function	Elongation factor HAMAP-Rule MF_00118 RuleBase RU000325 EMBL ACU94665.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	GTP binding Inferred from electronic annotation. Source: HAMAP GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	19 – 26	8	GTP By similarity HAMAP-Rule MF_00118
	Nucleotide binding	87 – 91	5	GTP By similarity HAMAP-Rule MF_00118
	Nucleotide binding	142 – 145	4	GTP By similarity HAMAP-Rule MF_00118

Sequences

	Sequence		Length	Mass (Da)
	C7MP25 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: 5D818367D5660786	FASTA	400	44,374
	10 20 30 40 50 60 MAKEKFERTK PHVNIGTIGH VDHGKTTLTA AISKTLSSND GSHGTAHADF TAFEDIDKAP 70 80 90 100 110 120 EERERGITIS IAHIEYETDK RHYAHVDCPG HADYVKNMIT GAAQMDGAIL VIAATDGPMA 130 140 150 160 170 180 QTREHILLAR QVGVPYIVVF LNKCDMVDDE ELLELVEMEV RDLLSSYDFP GDETPIIRGS 190 200 210 220 230 240 ALKALEGEKE WQDKIWELMD AVDEWIPTPT RDTEKPFLMA IEDVMTIPGR GTVVTGRVER 250 260 270 280 290 300 GVLHVGDELE ILGIRETQKT TCTGVEMFRK LLDEAEAGDN IGALLRGIKR EEVVRGQVLC 310 320 330 340 350 360 KPGSVTPHTE FKGQIYVLTK EEGGRHTPFF DGYRPQFYFR TTDITGVVHL PEGTEMVMPG 370 380 390 400 DNVEIKGELI HPVAMEEGLK FAIREGGRTV GSGRVTEIIK

References

[1]

"Complete genome sequence of Cryptobacterium curtum type strain (12-3)." Mavrommatis K., Pukall R., Rohde C., Chen F., Sims D., Brettin T., Kuske C., Detter J.C., Han C., Lapidus A., Copeland A., Glavina Del Rio T., Nolan M., Lucas S., Tice H., Cheng J.F., Bruce D., Goodwin L. , Pitluck S., Ovchinnikova G., Pati A., Ivanova N., Chen A., Palaniappan K., Chain P., D'haeseleer P., Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Rohde M., Klenk H.P., Kyrpides N.C. Stand. Genomic Sci. 1:93-100(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700683 / DSM 15641 / 12-3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001682 Genomic DNA. Translation: ACU94665.1.
RefSeq	YP_003151347.1. NC_013170.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	469378.Ccur_09710. C7MP25.
Proteomic databases
PRIDE	C7MP25.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACU94665; ACU94665; Ccur_09710.
GeneID	8375178.
KEGG	ccu:Ccur_09710.
PATRIC	21525745. VBICryCur116861_0925.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0050.
HOGENOM	HOG000229290.
KO	K02358.
OMA	CEFVGYN.
ProtClustDB	CLSK2555755.
Enzyme and pathway databases
BioCyc	CCUR469378:GH4Z-970-MONOMER.
Family and domain databases
HAMAP	MF_00118_B. EF_Tu_B.
InterPro	IPR000795. EF_GTP-bd_dom. IPR005225. Small_GTP-bd_dom. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004161. Transl_elong_EFTu/EF1A_2. IPR004541. Transl_elong_EFTu/EF1A_bac/org. IPR004160. Transl_elong_EFTu/EF1A_C. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SUPFAM	SSF50465. Elong_init_C. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00485. EF-Tu. 1 hit. TIGR00231. small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C7MP25_CRYCD

Accession

Primary (citable) accession number: C7MP25

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)