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C7MMU7 (C7MMU7_CRYCD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase HAMAP MF_00110

EC=4.2.3.4 HAMAP MF_00110
Gene names
Name:aroB HAMAP MF_00110
Ordered Locus Names:Ccur_05160
OrganismCryptobacterium curtum (strain ATCC 700683 / DSM 15641 / 12-3) [Complete proteome] [HAMAP]
Taxonomic identifier469378 [NCBI]
Taxonomic lineageBacteriaActinobacteriaCoriobacteridaeCoriobacterialesCoriobacterineaeCoriobacteriaceaeCryptobacterium

Protein attributes

Sequence length368 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family. HAMAP MF_00110

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis HAMAP MF_00110
   Cellular componentCytoplasm HAMAP MF_00110
   LigandNAD HAMAP MF_00110
   Molecular functionLyase HAMAP MF_00110 EMBL ACU94237.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
C7MMU7 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: DB20535DF6EE22F7

FASTA36839,439
        10         20         30         40         50         60 
MPNVKVVVNL TNAPSYDVRI GEGISSSLGE RIRSLVPQAS RAVIISDSNV APLYVQPIRA 

        70         80         90        100        110        120 
SLKEAALRPL DIVVPAGEPS KSIECLGEIW RALASKQVDR DCVVVALGGG VVGDLAGFAA 

       130        140        150        160        170        180 
ATYLRGVSFV QVPTTLLAMV DSSVGGKTGI DLPEGKNLAG SFLQPRYVCA DLDTLSTLDG 

       190        200        210        220        230        240 
REWTCGLGEI AKSAVIDSDE FFFWLVEHAT DIAQRKSDIV QEAIMRCVVF KANVVADDEF 

       250        260        270        280        290        300 
ERSGRRACLN YGHTLGHAIE TLAGLGTYSH GACVAEGMRF AARLGAALAG ASLDFVHEQD 

       310        320        330        340        350        360 
KLLDTLGLVP LDFSAAVDDI IDVMKNDKKS RAGKINFILP RDVGSWTLQT VEEDVLREHL 


DAWARSKG 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001682 Genomic DNA. Translation: ACU94237.1.
RefSeqYP_003150919.1. NC_013170.1.

3D structure databases

ProteinModelPortalC7MMU7.
ModBaseSearch...

Protein-protein interaction databases

STRINGC7MMU7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8374724.
GenomeReviewsGene locus Ccur_05160 in contig CP001682_GR.
KEGGccu:Ccur_05160.
PATRIC21524845. VBICryCur116861_0498.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAGTFTQPD.
ProtClustDBCLSK2555451.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC7MMU7_CRYCD
AccessionPrimary (citable) accession number: C7MMU7
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: December 14, 2011
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)