C7MEW4 (C7MEW4_BRAFD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase HAMAP MF_01554 RuleBase RU004327
EC=5.4.2.10 HAMAP MF_01554 RuleBase RU004327

Gene names

Name:	glmM HAMAP MF_01554
Ordered Locus Names:	Bfae_23210

Organism

Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / NCIB 9860) [Complete proteome] [HAMAP]

Taxonomic identifier

446465 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Dermabacteraceae › Brachybacterium

Protein attributes

Sequence length	448 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554 RuleBase RU004327
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554 RuleBase RU004327
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554
Sequence similarities	Belongs to the phosphohexose mutase family. HAMAP MF_01554 RuleBase RU004326

Ontologies

Keywords
Ligand	Magnesium HAMAP MF_01554 RuleBase RU004326 Metal-binding HAMAP MF_01554 RuleBase RU004326
Molecular function	Isomerase HAMAP MF_01554 RuleBase RU004327
PTM	Phosphoprotein HAMAP MF_01554
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	104	1	Phosphoserine intermediate By similarity HAMAP MF_01554
	Metal binding	104	1	Magnesium; via phosphate group By similarity HAMAP MF_01554
	Metal binding	241	1	Magnesium By similarity HAMAP MF_01554
	Metal binding	243	1	Magnesium By similarity HAMAP MF_01554
	Metal binding	245	1	Magnesium By similarity HAMAP MF_01554
Amino acid modifications
	Modified residue	104	1	Phosphoserine By similarity HAMAP MF_01554

Sequences

	Sequence		Length	Mass (Da)
	C7MEW4 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: 7979C5E033471297	FASTA	448	46,653
	10 20 30 40 50 60 MARLFGTDGV RGRANGDITA ELAVELSVGA AHVLGTLGAF GGTRPRAIVA RDTRPSGDFL 70 80 90 100 110 120 SAAVSAGLAS AGVDVLDAEV LPTPGLAHLV RSTGADLGVM ISASHNPAPD NGIKFFARGG 130 140 150 160 170 180 TKLPDEVENA IEARLGEEWD RPEGTDVGTI TRYEGAIDAY VEHLVATLDR SLEGLTVVAD 190 200 210 220 230 240 CANGAASITG PEALRRAGAT VHVIGDLSDG GLINDGVGST HLGPLQAAVR ERGADIGVAF 250 260 270 280 290 300 DGDADRCLAV DADGEIIDGD QIMAILALDL KERGKLHDDT LVVTVMSNLG LKLAMKEHGI 310 320 330 340 350 360 VLGQTGVGDR YVLEEMNLGG YSIGGEQSGH VIIAEHATTG DGELTALHLL QRMAETGRTA 370 380 390 400 410 420 RELKNVMTRL PQALINVKDV DKAKATIDRG VSDAIEAAEK ELGEAGRVLL RPSGTEPVVR 430 440 VMVEAPTDEQ AHEIAERLAV VVRERVGL

References

[1]

"Complete genome sequence of Brachybacterium faecium type strain (Schefferle 6-10)." Lapidus A., Pukall R., Labuttii K., Copeland A., Del Rio T.G., Nolan M., Chen F., Lucas S., Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavrommatis K. , Chen A., Palaniappan K., D'haeseleer P., Chain P., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P. Stand. Genomic Sci. 1:3-11(2009) [PubMed: 21304631] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43885 / DSM 4810 / NCIB 9860.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001643 Genomic DNA. Translation: ACU86114.1.
RefSeq	YP_003155704.1. NC_013172.1.
3D structure databases
ProteinModelPortal	C7MEW4.
ModBase	Search...
Protein-protein interaction databases
STRING	C7MEW4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8400867.
GenomeReviews	Gene locus Bfae_23210 in contig CP001643_GR.
KEGG	bfa:Bfae_23210.
PATRIC	21176327. VBIBraFae133938_2295.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	GVGSTHL.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 2 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C7MEW4_BRAFD

Accession

Primary (citable) accession number: C7MEW4

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	December 14, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)