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C7MEJ9 (C7MEJ9_BRAFD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Isocitrate dehydrogenase, NADP-dependent, monomeric type EMBL ACU86006.1
EC=1.1.1.42 EMBL ACU86006.1
Gene names
Ordered Locus Names:Bfae_22050
OrganismBrachybacterium faecium (strain ATCC 43885 / DSM 4810 / NCIB 9860) [Complete proteome] [HAMAP]
Taxonomic identifier446465 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Dermabacteraceae › Brachybacterium ›

Protein attributes

Sequence length746 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region130 – 1378Substrate binding By similarity PIRSR PIRSR009407-2

Sites

Metal binding3481Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5501Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5541Magnesium or manganese By similarity PIRSR PIRSR009407-3
Binding site1431Substrate By similarity PIRSR PIRSR009407-2
Binding site5491Substrate By similarity PIRSR PIRSR009407-2
Site2531Critical for catalysis By similarity PIRSR PIRSR009407-1
Site4181Critical for catalysis By similarity PIRSR PIRSR009407-1

Sequences

Sequence LengthMass (Da)Tools
C7MEJ9 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 25BCD3309E9F8372

FASTA74680,213
        10         20         30         40         50         60 
MARIIYTHTD EAPMLATASF LPILDAFSDT AGIEVTTRDI SLAGRIVAAF SELLPEDQRE 

        70         80         90        100        110        120 
ADALAELGEL AKTPEANIIK LPNISASVPQ LKAAVAELQG QGIALPDYPE SPSTEEEKDI 

       130        140        150        160        170        180 
RARYNSVMGS AVNPVLREGN SDRRAPSAVK NFAKKHPHRM GEWAKESKTS VVTMGENDFA 

       190        200        210        220        230        240 
SNEQSVISEG EDTFSIVHVA SDGTETVLKP SLPILAGEVV DSTVMRAAAL DEFLAAQIAA 

       250        260        270        280        290        300 
AKEQGVLFSL HLKATMMKVS DPILFGHAVR AFFPTLFSQY GEQLAAAGLS PDNGLGGILA 

       310        320        330        340        350        360 
GIDELDASVR DGVRAAIDED LAAGPDLAMV NSHKGITNLH VPSDVIIDAS MPAMIRGGGK 

       370        380        390        400        410        420 
MWNKDDAEQD TLAVIPDSSY AGVYAATVED CQAHGAFDPT TMGTVPNVGL MAQKAEEYGS 

       430        440        450        460        470        480 
HDKTFKIEAD GRVEVRDGSG TAVMSHEVSA GDIFRACQAK DAPIRDWVQL AVRRSRESGM 

       490        500        510        520        530        540 
PAVFWLDESR AHDRNLITKV NAYLAQPIDG KDTGDLDIRI LDPLEATKHT LARVRRGEDT 

       550        560        570        580        590        600 
ISVTGNVLRD YLTDLFPILE LGTSAKMLSV VPLMNGGGLF ETGAGGSAPK HVQQLVEEDY 

       610        620        630        640        650        660 
LRWDSLGEFL ALAESLRHLA RTAENERARV LADALDRATE TLLNEGKSPQ RKLGSIDNRG 

       670        680        690        700        710        720 
SHFYLALYWA QELAAQSEDT ELATAFAPIA KELTDGEQTI AEELLAVQGK PADIGGYYRP 

       730        740 
DLDKTGAVMR PSATFNRILE EISAAL

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001643 Genomic DNA. Translation: ACU86006.1.
RefSeqYP_003155596.1. NC_013172.1.

3D structure databases

ProteinModelPortalC7MEJ9.
ModBaseSearch...

Protein-protein interaction databases

STRING446465.Bfae_22050.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACU86006; ACU86006; Bfae_22050.
GeneID8400751.
KEGGbfa:Bfae_22050.
PATRIC21176105. VBIBraFae133938_2184.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2838.
HOGENOMHOG000240860.
KOK00031.
OMAFRMCQTK.
ProtClustDBCLSK867411.

Enzyme and pathway databases

BioCycBFAE446465:GH3P-2200-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 3 hits.
InterProIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamPF03971. IDH. 1 hit.
[Graphical view]
PIRSFPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsTIGR00178. monomer_idh. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC7MEJ9_BRAFD
AccessionPrimary (citable) accession number: C7MEJ9
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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