C7MC96 (C7MC96_BRAFD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361
Short name=Poly(P)/ATP NAD kinase HAMAP MF_00361
EC=2.7.1.23 HAMAP MF_00361

Gene names

Name:	ppnK HAMAP MF_00361
Ordered Locus Names:	Bfae_13660

Organism

Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / NCIB 9860) [Complete proteome] [HAMAP]

Taxonomic identifier

446465 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Dermabacteraceae › Brachybacterium

Protein attributes

Sequence length	314 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361 SAAS SAAS002504
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361 SAAS SAAS002504
Cofactor	Divalent metal ions By similarity. HAMAP MF_00361 SAAS SAAS002504
Subcellular location	Cytoplasm By similarity HAMAP MF_00361 SAAS SAAS002504.
Sequence similarities	Belongs to the NAD kinase family. HAMAP MF_00361

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00361 SAAS SAAS002504
Ligand	ATP-binding HAMAP MF_00361 SAAS SAAS002504 NAD HAMAP MF_00361 SAAS SAAS002504 NADP HAMAP MF_00361 SAAS SAAS002504 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00361 SAAS SAAS002504 EMBL ACU85203.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C7MC96 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: 3A978911650A0BE7	FASTA	314	34,122
	10 20 30 40 50 60 MRRFLLYVHT GRRAALRAML SVLEELRLRN VRAVVVDEQV EEILALPEDM APPKLITFLT 70 80 90 100 110 120 NGAVDVRAAV SAADVVELGI VLGGDGTILR ALEAVREADI PVHGVNLGHV GFLAESEVED 130 140 150 160 170 180 LSITVARLLD GDYDIEKRST LDITVLDSED ELVDHHWALN EASLEKADRQ KMINVAIEID 190 200 210 220 230 240 GRPVSSFGAD GVLLSTSTGS TAYAFSAGGP VIWPEVDAMM LIPLAAHALF ARPLVLGRSS 250 260 270 280 290 300 EAAVEMTLDN REDGILTLDG RRGADITAGM RIEARLSPRS VRLARLAPTP FADRLVEKFQ 310 LPVVGWRGRG PRTR

References

[1]

"Complete genome sequence of Brachybacterium faecium type strain (Schefferle 6-10)." Lapidus A., Pukall R., Labuttii K., Copeland A., Del Rio T.G., Nolan M., Chen F., Lucas S., Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavrommatis K. , Chen A., Palaniappan K., D'haeseleer P., Chain P., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P. Stand. Genomic Sci. 1:3-11(2009) [PubMed: 21304631] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43885 / DSM 4810 / NCIB 9860.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001643 Genomic DNA. Translation: ACU85203.1.
RefSeq	YP_003154793.1. NC_013172.1.
3D structure databases
ProteinModelPortal	C7MC96.
ModBase	Search...
Protein-protein interaction databases
STRING	C7MC96.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8399913.
GenomeReviews	Gene locus Bfae_13660 in contig CP001643_GR.
KEGG	bfa:Bfae_13660.
PATRIC	21174409. VBIBraFae133938_1364.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	GPVVWPE.
Family and domain databases
HAMAP	MF_00361. NAD_kinase. [Tree]
InterPro	IPR016064. ATP-NAD_kinase_PpnK-typ. IPR017438. ATP-NAD_kinase_PpnK-typ_a/b. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. polyP/ATP_NADK_prd. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit. G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KO	K00858.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
SUPFAM	SSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C7MC96_BRAFD

Accession

Primary (citable) accession number: C7MC96

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	December 14, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)