C7MA46 (C7MA46_BRAFD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
L-arabinose isomerase HAMAP MF_00519
EC=5.3.1.4 HAMAP MF_00519

Gene names

Name:	araA HAMAP MF_00519
Ordered Locus Names:	Bfae_29550

Organism

Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / NCIB 9860) [Complete proteome] [HAMAP]

Taxonomic identifier

446465 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Dermabacteraceae › Brachybacterium

Protein attributes

Sequence length	502 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity. HAMAP MF_00519 SAAS SAAS003762
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519 SAAS SAAS003762
Cofactor	Binds 1 manganese ion per subunit By similarity. HAMAP MF_00519 SAAS SAAS003762
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519 SAAS SAAS003762
Sequence similarities	Belongs to the arabinose isomerase family. HAMAP MF_00519

Ontologies

Keywords
Biological process	Arabinose catabolism HAMAP MF_00519 SAAS SAAS003762 Carbohydrate metabolism
Ligand	Manganese HAMAP MF_00519 SAAS SAAS003762 Metal-binding HAMAP MF_00519 SAAS SAAS003762
Molecular function	Isomerase HAMAP MF_00519 SAAS SAAS003762 EMBL ACU86716.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: HAMAP fucose metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: HAMAP L-fucose isomerase activity Inferred from electronic annotation. Source: InterPro manganese ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	307	1	Manganese By similarity HAMAP MF_00519
	Metal binding	334	1	Manganese By similarity HAMAP MF_00519
	Metal binding	351	1	Manganese By similarity HAMAP MF_00519
	Metal binding	450	1	Manganese By similarity HAMAP MF_00519

Sequences

	Sequence		Length	Mass (Da)
	C7MA46 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: 2A90BB722645A201	FASTA	502	55,035
	10 20 30 40 50 60 MDNPFTAREI WFLTGSQGLY GPETLVQVAE QSRTIAETLD AASDIPVKIV WKPVLTDRDA 70 80 90 100 110 120 IREIALAANA DPACVGVIAW MHTFSPAKMW IQGLDALRTP LLHLHTQANV ELPWSTIDMD 130 140 150 160 170 180 FMNLNQAAHG DREFGYIATR LGVDRKTVVG HASDEGVQSK IGRWARAATG WAEMHSLKLA 190 200 210 220 230 240 RFGDNMRGVA VTEGDKTEAE LRLGVSVNTW GVNDLVTVVD AVDDRDVDAL VAEYEELYEV 250 260 270 280 290 300 APELRKGGER HESLRYGARQ EIGLRTFLEE GGFGAFTTNF EDLGGLRQLP GLAVQRLMAD 310 320 330 340 350 360 GYGFGAEGDW KTAILVRVAA VMGHGLPGGA SLMEDYTYEL TPGREKILGA HMLEVSPSLT 370 380 390 400 410 420 TQKPTLEIHP LGIGDREDPV RLKFTADPGP AVVVALSDMR ERFRLVANVV DVVEPDEELP 430 440 450 460 470 480 NLPVACAVWE PKPDFATSAE CWLTAGAAHH TVMSNAVDLE TWEDLATIGD LELAIIDEDT 490 500 TVRSFAQDLR TNQVFHRLAQ GF

References

[1]

"Complete genome sequence of Brachybacterium faecium type strain (Schefferle 6-10)." Lapidus A., Pukall R., Labuttii K., Copeland A., Del Rio T.G., Nolan M., Chen F., Lucas S., Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavrommatis K. , Chen A., Palaniappan K., D'haeseleer P., Chain P., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P. Stand. Genomic Sci. 1:3-11(2009) [PubMed: 21304631] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43885 / DSM 4810 / NCIB 9860.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001643 Genomic DNA. Translation: ACU86716.1.
RefSeq	YP_003156306.1. NC_013172.1.
3D structure databases
ProteinModelPortal	C7MA46.
ModBase	Search...
Protein-protein interaction databases
STRING	C7MA46.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8401499.
GenomeReviews	Gene locus Bfae_29550 in contig CP001643_GR.
KEGG	bfa:Bfae_29550.
PATRIC	21177601. VBIBraFae133938_2920.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EVCPTIA.
ProtClustDB	PRK02929.
Family and domain databases
HAMAP	MF_00519. Arabinose_Isome. [Tree]
InterPro	IPR024664. Ara_Isoase_C. IPR004216. Fuc/Ara_isomerase_C. IPR009015. Fucose_isomerase_N/cen. IPR003762. Lara_isomerase. [Graphical view]
KO	K01804.
Pfam	PF11762. Arabinose_Iso_C. 1 hit. PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF50443. Fuc_isomerase_C. 1 hit. SSF53743. Fuc_isomerase_N. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C7MA46_BRAFD

Accession

Primary (citable) accession number: C7MA46

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)