C7M9L9 (C7M9L9_BRAFD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196
EC=1.1.1.17 HAMAP MF_00196

Gene names

Name:	mtlD HAMAP MF_00196
Ordered Locus Names:	Bfae_07050

Organism

Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / NCIB 9860) [Complete proteome] [HAMAP]

Taxonomic identifier

446465 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Dermabacteraceae › Brachybacterium

Protein attributes

Sequence length	379 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196 SAAS SAAS000669
Sequence similarities	Belongs to the mannitol dehydrogenase family. HAMAP MF_00196

Ontologies

Keywords
Ligand	NAD HAMAP MF_00196 SAAS SAAS000669
Molecular function	Oxidoreductase HAMAP MF_00196 SAAS SAAS023028 EMBL ACU84563.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro mannitol-1-phosphate 5-dehydrogenase activity Inferred from electronic annotation. Source: HAMAP nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	3 – 14	12	NAD By similarity HAMAP MF_00196

Sequences

	Sequence		Length	Mass (Da)
	C7M9L9 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: CB3D15CDD8CBEC00	FASTA	379	40,227
	10 20 30 40 50 60 MKAVHFGAGN IGRGFVGLLL HEAGYEVVFS DVAAPLVEQL QQAESYTVST VGQRPATTVV 70 80 90 100 110 120 DGFRALNSAQ DPEGLSEEIA SADLVTTAVG AGILRFVAPG IAAGIAARPS GAPPLAVLAC 130 140 150 160 170 180 ENAINATDLL EQEIRTNYQG DDLEEKAVFA NTAVDRIVPV QAEGAGLDVT VEDFYEWAVE 190 200 210 220 230 240 RGPFDGHEPD IPGITWVEDL EPYIERKLFT VNTGHATTAW HGWEAGHATI AEAIRDPAVA 250 260 270 280 290 300 VEVESVLGET SALLSAKHGF GADEMASYRT KVLGRFANEA LPDPVDRVGR APLRKLSRHD 310 320 330 340 350 360 RIIGPAAELA ERDLPYEGLL AAFAAALAFA PAEDDEAQRL QELLRSADPD AATVEITGLE 370 PGHPLYAEVR ALVAARSRA

References

[1]

"Complete genome sequence of Brachybacterium faecium type strain (Schefferle 6-10)." Lapidus A., Pukall R., Labuttii K., Copeland A., Del Rio T.G., Nolan M., Chen F., Lucas S., Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavrommatis K. , Chen A., Palaniappan K., D'haeseleer P., Chain P., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P. Stand. Genomic Sci. 1:3-11(2009) [PubMed: 21304631] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43885 / DSM 4810 / NCIB 9860.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001643 Genomic DNA. Translation: ACU84563.1.
RefSeq	YP_003154153.1. NC_013172.1.
3D structure databases
ProteinModelPortal	C7M9L9.
ModBase	Search...
Protein-protein interaction databases
STRING	C7M9L9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8399253.
GenomeReviews	Gene locus Bfae_07050 in contig CP001643_GR.
KEGG	bfa:Bfae_07050.
PATRIC	21173053. VBIBraFae133938_0695.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	FANTAVD.
ProtClustDB	PRK02318.
Family and domain databases
HAMAP	MF_00196. Mannitol_dehydrog. [Tree]
InterPro	IPR008927. 6-PGluconate_DH_C-like. IPR013328. DH_multihelical. IPR023028. Mannitol_1_phos_5_DH. IPR000669. Mannitol_DH. IPR013118. Mannitol_DH_C. IPR013131. Mannitol_DH_N. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KO	K00009.
Pfam	PF01232. Mannitol_dh. 1 hit. PF08125. Mannitol_dh_C. 1 hit. [Graphical view]
PRINTS	PR00084. MTLDHDRGNASE.
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C7M9L9_BRAFD

Accession

Primary (citable) accession number: C7M9L9

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)