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C7M7B7 (C7M7B7_CAPOD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Orotate phosphoribosyltransferase HAMAP MF_01208
Short name=OPRT HAMAP MF_01208
Short name=OPRTase HAMAP MF_01208
EC=2.4.2.10 HAMAP MF_01208
Gene names
Name:pyrE HAMAP MF_01208
Ordered Locus Names:Coch_1652
OrganismCapnocytophaga ochracea (strain ATCC 27872 / DSM 7271 / JCM 12966 / VPI 2845) (Bacteroides ochraceus) [Complete proteome] [HAMAP]
Taxonomic identifier521097 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Capnocytophaga

Protein attributes

Sequence length213 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) By similarity. HAMAP MF_01208 SAAS SAAS004467

Catalytic activity

Orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_01208 SAAS SAAS023031

Cofactor

Magnesium By similarity. HAMAP MF_01208

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2. HAMAP MF_01208 SAAS SAAS023031

Subunit structure

Homodimer By similarity. HAMAP MF_01208 SAAS SAAS004467

Sequence similarities

Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily. HAMAP MF_01208

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region126 – 13495-phosphoribose 1-diphosphate binding By similarity HAMAP MF_01208

Sites

Binding site10015-phosphoribose 1-diphosphate; shared with dimeric partner By similarity HAMAP MF_01208
Binding site10415-phosphoribose 1-diphosphate; shared with dimeric partner By similarity HAMAP MF_01208
Binding site10615-phosphoribose 1-diphosphate; shared with dimeric partner By similarity HAMAP MF_01208
Binding site1301Orotate By similarity HAMAP MF_01208

Sequences

Sequence LengthMass (Da)Tools
C7M7B7 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: D1E9FAFB51DCF429

FASTA21323,970
        10         20         30         40         50         60 
MILDSITAQN TAEFLLQINA IKLNSENYFT WASGWKSPIY CDNRIILSFP EVRSYFASVL 

        70         80         90        100        110        120 
ARGVKEKFPE VQVIAGVATG AIGIGMLVAN ALELPFVYVR PEPKKHGRQN QIEGFLRPEQ 

       130        140        150        160        170        180 
KVVVVEDLIS TGMSSLNAVK ALRDSGAEVL GMVALFSYNF DVANERFTEE KVPLYTAGDY 

       190        200        210 
DSLLEKALLF GRIKKEDLEM LQQWRKSPDT WKQ

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001632 Genomic DNA. Translation: ACU93197.1.
RefSeqYP_003141758.1. NC_013162.1.

3D structure databases

ProteinModelPortalC7M7B7.
ModBaseSearch...

Protein-protein interaction databases

STRINGC7M7B7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8368098.
GenomeReviewsGene locus Coch_1652 in contig CP001632_GR.
KEGGcoc:Coch_1652.
PATRIC21272090. VBICapOch61160_1632.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMALPMTYVR.
ProtClustDBPRK00455.

Family and domain databases

HAMAPMF_01208. PyrE.
[Tree]
InterProIPR004467. Or_phspho_trans_clade-1.
IPR023031. Orotate_PribosylTferase.
IPR000836. PRibTrfase.
[Graphical view]
KOK00762.
PfamPF00156. Pribosyltran. 1 hit.
[Graphical view]
TIGRFAMsTIGR00336. PyrE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC7M7B7_CAPOD
AccessionPrimary (citable) accession number: C7M7B7
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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