Skip Header

Contribute Send feedback
Read comments (?) or add your own

C7M4X6 (C7M4X6_CAPOD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
Quorum-sensing autoinducer 2 (AI-2), LuxS EMBL ACU92766.1
EC=4.4.1.21 EMBL ACU92766.1
Gene names
Ordered Locus Names:Coch_1216
OrganismCapnocytophaga ochracea (strain ATCC 27872 / DSM 7271 / JCM 12966 / VPI 2845) (Bacteroides ochraceus) [Complete proteome] [HAMAP]
Taxonomic identifier521097 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Capnocytophaga

Protein attributes

Sequence length159 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD) By similarity. SAAS SAAS003815

Catalytic activity

S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = L-homocysteine + (4S)-4,5-dihydroxypentan-2,3-dione. SAAS SAAS003815

Cofactor

Binds 1 iron ion per subunit By similarity. SAAS SAAS003815

Subunit structure

Homodimer By similarity. SAAS SAAS003815

Sequences

Sequence LengthMass (Da)Tools
C7M4X6 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 5F11A1CC06054FD0

FASTA15918,397
        10         20         30         40         50         60 
MERIASFCID HLKLERGIYV SRKDYVGNEV LTSFDIRMKL PYREPVLGSP ETHTIEHLAA 

        70         80         90        100        110        120 
TWLRNNPEWK DKIIYWGPMG CMTGNYLILA GDYTSKDIAP LITELFEYIA NFEGDIPGAS 

       130        140        150 
ALECGNFYNN NLPFAKYEAK KYLEETLYHL TDKNLNYPK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001632 Genomic DNA. Translation: ACU92766.1.
RefSeqYP_003141327.1. NC_013162.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC7M4X6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8367644.
GenomeReviewsGene locus Coch_1216 in contig CP001632_GR.
KEGGcoc:Coch_1216.
PATRIC21271178. VBICapOch61160_1192.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMATTFDIRM.
ProtClustDBPRK02260.

Family and domain databases

InterProIPR011249. Metalloenz_metal-bd.
IPR003815. S-ribosylhomocysteinase.
[Graphical view]
Gene3DG3DSA:3.30.1360.80. S-ribosylhomocysteinase. 1 hit.
KOK07173.
PfamPF02664. LuxS. 1 hit.
[Graphical view]
PRINTSPR01487. LUXSPROTEIN.
ProDomPD013172. S-ribosylhomocysteinase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF63411. Metalloenz_metal-bd. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC7M4X6_CAPOD
AccessionPrimary (citable) accession number: C7M4X6
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: December 14, 2011
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info