C7M2X0 (C7M2X0_ACIFD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Elongation factor Tu HAMAP-Rule MF_00118
Short name=EF-Tu HAMAP-Rule MF_00118

Gene names

Name:	tuf HAMAP-Rule MF_00118
Ordered Locus Names:	Afer_0396

Organism

Acidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP) [Complete proteome] [HAMAP]

Taxonomic identifier

525909 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Acidimicrobidae › Acidimicrobiales › Acidimicrobineae › Acidimicrobiaceae › Acidimicrobium › Acidimicrobium ferrooxidans

Protein attributes

Sequence length	395 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118 RuleBase RU000325
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00118
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00118.
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. HAMAP-Rule MF_00118 RuleBase RU000325

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm HAMAP-Rule MF_00118
Ligand	GTP-binding HAMAP-Rule MF_00118 RuleBase RU000323 Nucleotide-binding
Molecular function	Elongation factor HAMAP-Rule MF_00118 RuleBase RU000325 EMBL ACU53364.1 Nucleotidyltransferase EMBL ACU53364.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	GTP binding Inferred from electronic annotation. Source: HAMAP GTPase activity Inferred from electronic annotation. Source: InterPro nucleotidyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	19 – 26	8	GTP By similarity HAMAP-Rule MF_00118
	Nucleotide binding	82 – 86	5	GTP By similarity HAMAP-Rule MF_00118
	Nucleotide binding	137 – 140	4	GTP By similarity HAMAP-Rule MF_00118

Sequences

	Sequence		Length	Mass (Da)
	C7M2X0 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: 8867D58FF6EB512C	FASTA	395	43,701
	10 20 30 40 50 60 MGKQKFERTK PHINIGTMGH IDHGKTTLTA AITKVLSEKN PNVKFKPFDQ IDNAPEEKAR 70 80 90 100 110 120 GITISISHVE YETEKRHYAH VDMPGHADYI KNMITGAAQV DGAILVVAAT DGPMPQTREH 130 140 150 160 170 180 VLLARQVGVP YIVVALNKAD MVDDEELLDL VELEVRELLN QYEFPGDDTP IVRVSALKAL 190 200 210 220 230 240 EGDPVWEEKI VELMNAVDEY IPEPQRPVDR PFLMPIEDVF TISGRGTVVT GKVETGKVHV 250 260 270 280 290 300 GDEVEIVGLR PTQKTVATGV EMFNKLLDEG QAGDNIGVLL RGTKKTDVER GQVLCKPGSI 310 320 330 340 350 360 TPHTTFEANV YVLTKDEGGR HKPFFNNYRP QFYFRTTDVT GTITLPEGTE MVMPGDNIVM 370 380 390 TVELLKPVAM DEGLRFAIRE GGRTVGAGRV VKIIK

References

[1]

"Complete genome sequence of Acidimicrobium ferrooxidans type strain (ICP)." Clum A., Nolan M., Lang E., Glavina Del Rio T., Tice H., Copeland A., Cheng J.-F., Lucas S., Chen F., Bruce D., Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K. , Goeker M., Spring S., Land M., Hauser L., Chang Y.-J., Jeffries C.C., Chain P., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.-P., Lapidus A. Stand. Genomic Sci. 1:38-45(2009) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 10331 / JCM 15462 / NBRC 103882 / ICP.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001631 Genomic DNA. Translation: ACU53364.1.
RefSeq	YP_003109037.1. NC_013124.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	525909.Afer_0396.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACU53364; ACU53364; Afer_0396.
GeneID	8322455.
KEGG	afo:Afer_0396.
PATRIC	20640411. VBIAciFer34262_0415.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0050.
HOGENOM	HOG000229290.
KO	K02358.
OMA	HTDFEAN.
Enzyme and pathway databases
BioCyc	AFER525909:GHMR-409-MONOMER.
Family and domain databases
HAMAP	MF_00118_B. EF_Tu_B.
InterPro	IPR000795. EF_GTP-bd_dom. IPR005225. Small_GTP-bd_dom. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004161. Transl_elong_EFTu/EF1A_2. IPR004541. Transl_elong_EFTu/EF1A_bac/org. IPR004160. Transl_elong_EFTu/EF1A_C. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SUPFAM	SSF50465. Elong_init_C. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00485. EF-Tu. 1 hit. TIGR00231. small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C7M2X0_ACIFD

Accession

Primary (citable) accession number: C7M2X0

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)