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Protein

Elongation factor Tu

Gene

tuf

Organism
Acidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi82 – 86GTPUniRule annotation5
Nucleotide bindingi137 – 140GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factorUniRule annotationImported, NucleotidyltransferaseImported, Transferase
Biological processProtein biosynthesis
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAFER525909:G1GEZ-411-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:Afer_0396Imported
OrganismiAcidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP)Imported
Taxonomic identifieri525909 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaAcidimicrobiiaAcidimicrobialesAcidimicrobiaceaeAcidimicrobium
Proteomesi
  • UP000000771 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiC7M2X0

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi525909.Afer_0396

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 205Tr-type GInterPro annotationAdd BLAST196

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili141 – 161Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CGV Bacteria
COG0050 LUCA
HOGENOMiHOG000229290
KOiK02358
OMAiYGHIDCP
OrthoDBiPOG091H00LA

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
HAMAPiMF_00118_B EF_Tu_B, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

C7M2X0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKQKFERTK PHINIGTMGH IDHGKTTLTA AITKVLSEKN PNVKFKPFDQ
60 70 80 90 100
IDNAPEEKAR GITISISHVE YETEKRHYAH VDMPGHADYI KNMITGAAQV
110 120 130 140 150
DGAILVVAAT DGPMPQTREH VLLARQVGVP YIVVALNKAD MVDDEELLDL
160 170 180 190 200
VELEVRELLN QYEFPGDDTP IVRVSALKAL EGDPVWEEKI VELMNAVDEY
210 220 230 240 250
IPEPQRPVDR PFLMPIEDVF TISGRGTVVT GKVETGKVHV GDEVEIVGLR
260 270 280 290 300
PTQKTVATGV EMFNKLLDEG QAGDNIGVLL RGTKKTDVER GQVLCKPGSI
310 320 330 340 350
TPHTTFEANV YVLTKDEGGR HKPFFNNYRP QFYFRTTDVT GTITLPEGTE
360 370 380 390
MVMPGDNIVM TVELLKPVAM DEGLRFAIRE GGRTVGAGRV VKIIK
Length:395
Mass (Da):43,701
Last modified:October 13, 2009 - v1
Checksum:i8867D58FF6EB512C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001631 Genomic DNA Translation: ACU53364.1
RefSeqiWP_015797865.1, NC_013124.1

Genome annotation databases

EnsemblBacteriaiACU53364; ACU53364; Afer_0396
KEGGiafo:Afer_0396

Similar proteinsi

Entry informationi

Entry nameiC7M2X0_ACIFD
AccessioniPrimary (citable) accession number: C7M2X0
Entry historyiIntegrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: March 28, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health