ID   C7M1M3_ACIFD            Unreviewed;       772 AA.
AC   C7M1M3;
DT   13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT   13-OCT-2009, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00022419};
GN   OrderedLocusNames=Afer_0101 {ECO:0000313|EMBL:ACU53072.1};
OS   Acidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 /
OS   ICP).
OC   Bacteria; Actinomycetota; Acidimicrobiia; Acidimicrobiales;
OC   Acidimicrobiaceae; Acidimicrobium.
OX   NCBI_TaxID=525909 {ECO:0000313|EMBL:ACU53072.1, ECO:0000313|Proteomes:UP000000771};
RN   [1] {ECO:0000313|EMBL:ACU53072.1, ECO:0000313|Proteomes:UP000000771}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10331 / JCM 15462 / NBRC 103882 / ICP
RC   {ECO:0000313|Proteomes:UP000000771};
RX   PubMed=21304635; DOI=10.4056/sigs.1463;
RA   Clum A., Nolan M., Lang E., Glavina Del Rio T., Tice H., Copeland A.,
RA   Cheng J.F., Lucas S., Chen F., Bruce D., Goodwin L., Pitluck S.,
RA   Ivanova N., Mavrommatis K., Mikhailova N., Pati A., Chen A.,
RA   Palaniappan K., Goker M., Spring S., Land M., Hauser L., Chang Y.J.,
RA   Jeffries C.C., Chain P., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.P., Lapidus A.;
RT   "Complete genome sequence of Acidimicrobium ferrooxidans type strain
RT   (ICP).";
RL   Stand. Genomic Sci. 1:38-45(2009).
CC   -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC       for the tricarboxylic acid cycle. {ECO:0000256|ARBA:ARBA00003670}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC         phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC         Evidence={ECO:0000256|ARBA:ARBA00001071};
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DR   EMBL; CP001631; ACU53072.1; -; Genomic_DNA.
DR   AlphaFoldDB; C7M1M3; -.
DR   STRING; 525909.Afer_0101; -.
DR   KEGG; afo:Afer_0101; -.
DR   eggNOG; COG2352; Bacteria.
DR   HOGENOM; CLU_006557_2_0_11; -.
DR   Proteomes; UP000000771; Chromosome.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:InterPro.
DR   GO; GO:0015977; P:carbon fixation; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   PANTHER; PTHR30523:SF6; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:ACU53072.1};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Pyruvate {ECO:0000313|EMBL:ACU53072.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000771}.
FT   ACT_SITE        37
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10111"
FT   ACT_SITE        442
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10112"
SQ   SEQUENCE   772 AA;  84465 MW;  96356E482370E220 CRC64;
     MFNVLNVAEG ADDVTDLAKL APRSLGRIRL TPVLTAHPTE TKRRTILHTL QRIAHAPNAV
     DPSDLRLLWF TEELRSRRLE VADEVHTGLF YLTTSLFDAI PVVYRQLAAA RGVDADAIGV
     PVRFGSWIGG DRDGNPLVTA EVTKAAFVAN ATACLEAFRS RLDAVKRRLT HSMHFAAVSD
     AIVESIRNDE HDFVHLAPYV RTHYVDEPYR QKIYYLLARI DNQLHRLHND PEALDIAPLV
     GPDLETALRL IRDSLAAHGD TALAEGPLQD LVWQAATFGT HLASLDIRQE STVHHQAILE
     LFGDDPRLAG YWEADADDRL SMLLACLDHP PHARTPRTTL VADLVALFDT LTTVEAELGP
     AAIGSYVISM THHAADVIAV LVIARALGAD HLDITPLFET IADLECLESV MEQLFTLPAY
     LAHLERRALR QEVMLGYSDS TKDGGMAASA YALYRAQEAL IGLGERHAIT VELFHGRGGT
     VGRGGGPIAQ VARAHPRAAL RGTIRITEQG ETISHRYATT DRASATLLTA LGAFGGADDD
     TAPTDRAVMV TELVARSSEH AYRALTTSAG FDAYFRSVTP FPELTQLRIG SRPARRHQAD
     TGLATIRAIP WVFAWAQSRH TLPAWFGIGT GLATAREAHG DHAIREARAS WPFVAGMLDN
     VQIALAKADM RLARRYLDLA DDPTTAAAIF AVIEEEYERT VAETLRATGQ RRLLAWSPTL
     ADSLTVRNRV LAELNPLQVT ALGAWRSSRN PDDLTLVLRS INAIATVQKN SG
//