C7M0Z0 (C7M0Z0_ACIFD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-oxoglutarate dehydrogenase, E1 subunit EMBL ACU54648.1

Gene names

Ordered Locus Names:

Afer_1732

Organism

Acidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP) [Complete proteome] [HAMAP]

Taxonomic identifier

525909 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Acidimicrobidae › Acidimicrobiales › Acidimicrobineae › Acidimicrobiaceae › Acidimicrobium

Protein attributes

Sequence length	1277 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423

Ontologies

Keywords
Ligand	Thiamine pyrophosphate SAAS SAAS001017
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular function	oxoglutarate dehydrogenase (succinyl-transferring) activity Inferred from electronic annotation. Source: InterPro thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring acyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C7M0Z0 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: 844446DAD394B28C	FASTA	1,277	138,738
	10 20 30 40 50 60 MASAPDNSTV QHSASEQFGP NDWFVEEMAE RYRANPLLVP ESWRAYFEGE RVPDGVATKT 70 80 90 100 110 120 IATATAKELV GFEAPGVATP PTTATPAPTS PPHNGATPQT APFTPASSPE AVDPLTPPRS 130 140 150 160 170 180 SAPETAPHAS EPAVSTTPTV PSAQPLRGAQ GALARNMEAS LAVPTATSVR AVPTRALEVN 190 200 210 220 230 240 RATINDQLQR LGRSKVSFGH LVAWAIVRAL VEHPRMHASY VADADGRGHP GIVIPESVNL 250 260 270 280 290 300 GIAVDVQRPD GTRSLLVPVI RNADTLGPLG FFAAYDDAVR AVRSQQASPD LFVGATASIT 310 320 330 340 350 360 NPGTIGTEHS IPRLMPGQGV IVGVGAIAYP AAFQAADPRL LGELGVSRTI TLTSTYDHRI 370 380 390 400 410 420 IQGAESGQFL ATIAALLEGE QDFYDEIFSA LQVPYPPMRW QADHTSMQPD ATERLAKQVH 430 440 450 460 470 480 VQSLIHHYRV RGHLLATLDP LDLTRPTMSP ELDPATYGLT LWDLSRPFLA EGLVPGGQAS 490 500 510 520 530 540 LETILQVLRD TYCQTIGYEF MHIQSPDEKL WIQQRIEGSH QTLTKDDQLR ILATLNDAEA 550 560 570 580 590 600 FEKFLSTRYI GQKRFGLEGG ESAIVFLREV LDHAAETGTH AAVIGMAHRG RLNVLANIVG 610 620 630 640 650 660 KSYRTIFAEF EGNLDPSSVQ GSGDVKYHKG FEGHYRTASG SELPVTLASN PSHLEAVDPV 670 680 690 700 710 720 VEGMVRALQD QRGTLYEFGV LGILVHGDAS FAGQGVVAET LNLSQLPGYR TGGTVHLVIN 730 740 750 760 770 780 NQVGFTTNPS EARSSFYASD IAKTIQAPIF HVNGDDPEAV ARCARLAVEY RATFHKDVVV 790 800 810 820 830 840 DLICYRRHGH NEGDEPSYTQ PVMYHVIEQH PSVRRLYADQ LVRSGAISED EADQALEAYL 850 860 870 880 890 900 QRLATALAET REAAPPKPTE LPPEPARDVP LPIVTTAVDK AALDYVIETI HRVPEDFHLH 910 920 930 940 950 960 PKLARQFETR RALYEQGQLD WALGELAAYG TLLLEGHDVR LSGQDTRRGT FSHRHAALYD 970 980 990 1000 1010 1020 YETGAMVQPL ARLRDDEVPV PHASPIGRFM VYDSSLSEYA AMGFEYGYSL VQRSALVIWE 1030 1040 1050 1060 1070 1080 AQFGDFANGA QIVIDQFIAG ALDKWDQHSG LVLYLPHGYE GQGPEHSSAR LERFLALAAG 1090 1100 1110 1120 1130 1140 PNLAVVQPST AAQLFHLVRA QVARTPQRPL VVLTPKSLLR ARETRSAIAA FTDGGFQPVL 1150 1160 1170 1180 1190 1200 ADPLVDDGEL EPTSVRRLIL ASGKVAYEAM AKRAKGELAA PTAIVRVDQL YPWPREALAA 1210 1220 1230 1240 1250 1260 ALATFPNLAE LVWLQEEPEN MGAWPSVHEL LHRMDLNGAR LRHVSRVRAG SPATGSAAMH 1270 ALEQADLLRR ALEAPLP

References

[1]

"Complete genome sequence of Acidimicrobium ferrooxidans type strain (ICP)." Clum A., Nolan M., Lang E., Glavina Del Rio T., Tice H., Copeland A., Cheng J.-F., Lucas S., Chen F., Bruce D., Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K. , Goeker M., Spring S., Land M., Hauser L., Chang Y.-J., Jeffries C.C., Chain P., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.-P., Lapidus A. Stand. Genomic Sci. 1:38-45(2009) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 10331 / JCM 15462 / NBRC 103882 / ICP.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001631 Genomic DNA. Translation: ACU54648.1.
RefSeq	YP_003110321.1. NC_013124.1.
3D structure databases
ProteinModelPortal	C7M0Z0.
ModBase	Search...
Protein-protein interaction databases
STRING	C7M0Z0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8323823.
GenomeReviews	Gene locus Afer_1732 in contig CP001631_GR.
KEGG	afo:Afer_1732.
PATRIC	20643305. VBIAciFer34262_1833.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EGDEPAF.
ProtClustDB	PRK12270.
Family and domain databases
InterPro	IPR001078. 2-oxoacid_DH_actylTfrase. IPR011603. 2oxoglutarate_DH_E1. IPR023213. CAT-like_dom. IPR001017. DH_E1. IPR005475. Transketolase-like_Pyr-bd. [Graphical view]
Gene3D	G3DSA:3.30.559.10. CAT-like_dom. 1 hit.
KO	K00164.
PANTHER	PTHR23152. 2oxoglutarate_DH_E1. 1 hit.
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00676. E1_dh. 1 hit. PF02779. Transket_pyr. 1 hit. [Graphical view]
PIRSF	PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMART	SM00861. Transket_pyr. 1 hit. [Graphical view]
TIGRFAMs	TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C7M0Z0_ACIFD

Accession

Primary (citable) accession number: C7M0Z0

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)