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Protein

Glutamate decarboxylase

Gene

Afer_1640

Organism
Acidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:Afer_1640Imported
OrganismiAcidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP)Imported
Taxonomic identifieri525909 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaAcidimicrobiiaAcidimicrobialesAcidimicrobiaceaeAcidimicrobium
Proteomesi
  • UP000000771 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei282N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi525909.Afer_1640.

Structurei

3D structure databases

ProteinModelPortaliC7M0P8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CVK. Bacteria.
COG0076. LUCA.
HOGENOMiHOG000070228.
KOiK01580.
OMAiFEVEPRY.
OrthoDBiPOG091H06F5.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

C7M0P8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIRLARRHSS PRRHTFSKDL PINPLFVREL TEGVPRARLR SDGLGPDLAY
60 70 80 90 100
QVIHDEIAMD GNARLNLATF VTTWMEPQAD RLYAEAVDKN MIDKDEYPQT
110 120 130 140 150
AAIEGRCVRM LADLWHAPDP DTTIGVSTTG SSEACMLAGL ALKRRWQIAR
160 170 180 190 200
RATGAPTDRP NIVVSSAVQV VWEKFANYFE VEPRYVPVTP EHPTLDADGV
210 220 230 240 250
LAAVDERTIG VVPILGVTYT GVYEPVAEIA RALDELYERT GLDIPIHVDG
260 270 280 290 300
ASGGFVAPFL EPQLDWDFRL PRVVSINASG HKFGLVYPGL GWVVWRQATD
310 320 330 340 350
VPEELIFRVA YLGGDMPTLA LNFSRPGAQV LLQYYTFLRL GREGFTAVHA
360 370 380 390 400
SAQRVARMIA DELASLGPFE VIGDGRDIPV VAWRLRPGEV RPWDLNHLSH
410 420 430 440 450
ELRAYGWQVP AYPMPDAMSD VTVMRAVVRS EFSADMATLF LDDLAECVEV
460 470
LERHGTPPPV HPTVRESFHH
Length:470
Mass (Da):52,372
Last modified:October 13, 2009 - v1
Checksum:i0BADC41B0AFE7155
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001631 Genomic DNA. Translation: ACU54556.1.
RefSeqiWP_015799035.1. NC_013124.1.

Genome annotation databases

EnsemblBacteriaiACU54556; ACU54556; Afer_1640.
KEGGiafo:Afer_1640.
PATRICi20643115. VBIAciFer34262_1738.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001631 Genomic DNA. Translation: ACU54556.1.
RefSeqiWP_015799035.1. NC_013124.1.

3D structure databases

ProteinModelPortaliC7M0P8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi525909.Afer_1640.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACU54556; ACU54556; Afer_1640.
KEGGiafo:Afer_1640.
PATRICi20643115. VBIAciFer34262_1738.

Phylogenomic databases

eggNOGiENOG4105CVK. Bacteria.
COG0076. LUCA.
HOGENOMiHOG000070228.
KOiK01580.
OMAiFEVEPRY.
OrthoDBiPOG091H06F5.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiC7M0P8_ACIFD
AccessioniPrimary (citable) accession number: C7M0P8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: November 2, 2016
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.