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C7M0P8

- C7M0P8_ACIFD

UniProt

C7M0P8 - C7M0P8_ACIFD

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Protein

Glutamate decarboxylase

Gene

Afer_1640

Organism
Acidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

Pyridoxal phosphate.UniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciAFER525909:GHMR-1680-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:Afer_1640Imported
OrganismiAcidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP)Imported
Taxonomic identifieri525909 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaAcidimicrobidaeAcidimicrobialesAcidimicrobineaeAcidimicrobiaceaeAcidimicrobium
ProteomesiUP000000771: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi525909.Afer_1640.

Structurei

3D structure databases

ProteinModelPortaliC7M0P8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiMIGRLFN.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

C7M0P8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIRLARRHSS PRRHTFSKDL PINPLFVREL TEGVPRARLR SDGLGPDLAY
60 70 80 90 100
QVIHDEIAMD GNARLNLATF VTTWMEPQAD RLYAEAVDKN MIDKDEYPQT
110 120 130 140 150
AAIEGRCVRM LADLWHAPDP DTTIGVSTTG SSEACMLAGL ALKRRWQIAR
160 170 180 190 200
RATGAPTDRP NIVVSSAVQV VWEKFANYFE VEPRYVPVTP EHPTLDADGV
210 220 230 240 250
LAAVDERTIG VVPILGVTYT GVYEPVAEIA RALDELYERT GLDIPIHVDG
260 270 280 290 300
ASGGFVAPFL EPQLDWDFRL PRVVSINASG HKFGLVYPGL GWVVWRQATD
310 320 330 340 350
VPEELIFRVA YLGGDMPTLA LNFSRPGAQV LLQYYTFLRL GREGFTAVHA
360 370 380 390 400
SAQRVARMIA DELASLGPFE VIGDGRDIPV VAWRLRPGEV RPWDLNHLSH
410 420 430 440 450
ELRAYGWQVP AYPMPDAMSD VTVMRAVVRS EFSADMATLF LDDLAECVEV
460 470
LERHGTPPPV HPTVRESFHH
Length:470
Mass (Da):52,372
Last modified:October 13, 2009 - v1
Checksum:i0BADC41B0AFE7155
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001631 Genomic DNA. Translation: ACU54556.1.
RefSeqiWP_015799035.1. NC_013124.1.
YP_003110229.1. NC_013124.1.

Genome annotation databases

EnsemblBacteriaiACU54556; ACU54556; Afer_1640.
GeneIDi8323731.
KEGGiafo:Afer_1640.
PATRICi20643115. VBIAciFer34262_1738.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001631 Genomic DNA. Translation: ACU54556.1 .
RefSeqi WP_015799035.1. NC_013124.1.
YP_003110229.1. NC_013124.1.

3D structure databases

ProteinModelPortali C7M0P8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 525909.Afer_1640.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACU54556 ; ACU54556 ; Afer_1640 .
GeneIDi 8323731.
KEGGi afo:Afer_1640.
PATRICi 20643115. VBIAciFer34262_1738.

Phylogenomic databases

eggNOGi COG0076.
HOGENOMi HOG000070228.
KOi K01580.
OMAi MIGRLFN.
OrthoDBi EOG6TFCPW.

Enzyme and pathway databases

BioCyci AFER525909:GHMR-1680-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
InterProi IPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfami PF00282. Pyridoxal_deC. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 10331 / JCM 15462 / NBRC 103882 / ICPImported.

Entry informationi

Entry nameiC7M0P8_ACIFD
AccessioniPrimary (citable) accession number: C7M0P8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: October 29, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3