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Protein

dTDP-glucose 4,6-dehydratase

Gene

Dbac_2884

Organism
Desulfomicrobium baculatum (strain DSM 4028 / VKM B-1378) (Desulfovibrio baculatus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O.UniRule annotation

Cofactori

NAD(+)UniRule annotation

GO - Molecular functioni

  1. coenzyme binding Source: InterPro
  2. dTDP-glucose 4,6-dehydratase activity Source: UniProtKB-EC

GO - Biological processi

  1. nucleotide-sugar metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Enzyme and pathway databases

BioCyciDBAC525897:GI50-2946-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
dTDP-glucose 4,6-dehydrataseUniRule annotation (EC:4.2.1.46UniRule annotation)
Gene namesi
Ordered Locus Names:Dbac_2884Imported
OrganismiDesulfomicrobium baculatum (strain DSM 4028 / VKM B-1378) (Desulfovibrio baculatus)Imported
Taxonomic identifieri525897 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfomicrobiaceaeDesulfomicrobium
ProteomesiUP000002216 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi525897.Dbac_2884.

Structurei

3D structure databases

ProteinModelPortaliC7LUP4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG1088.
HOGENOMiHOG000168006.
KOiK01710.
OMAiGFIASHM.
OrthoDBiEOG6PZXCX.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR005888. dTDP_Gluc_deHydtase.
IPR001509. Epimerase_deHydtase_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR10366:SF41. PTHR10366:SF41. 1 hit.
PfamiPF01370. Epimerase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01181. dTDP_gluc_dehyt. 1 hit.

Sequencei

Sequence statusi: Complete.

C7LUP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHLLVTGGCG FIGSNFIQHM LASHEDVVIV NLDKLTYAGN RRNLAEEEAL
60 70 80 90 100
HLGRRYHFVH GDICDQELVP ELMKRFVFDA VLNFAAESHV DRSISDPFPF
110 120 130 140 150
VTTNVLGTQN LLEAARRAEI PRFVHISTDE VYGTLGPTGQ FTEDTPLAPN
160 170 180 190 200
SPYSASKASS DLLARAYFHT YGMPVMVTRC SNNYGPYQFP EKLIPLVYLK
210 220 230 240 250
ASRSEPIPVY GDGQNVRDWI YVMDHCRGVE ATLFKGQPGA VYNFGGDAER
260 270 280 290 300
TNLEVVRLIL RLTGKSEDLI THVTDRPGHD RRYAMAFARS TADLGWTPQH
310 320 330 340
SFEDGMARTL AWYKANEAWL DEVQSGAYRQ FMDNWYRTRQ A
Length:341
Mass (Da):38,548
Last modified:October 13, 2009 - v1
Checksum:i45C7A5C254FEB672
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001629 Genomic DNA. Translation: ACU90959.1.
RefSeqiYP_003159375.1. NC_013173.1.

Genome annotation databases

EnsemblBacteriaiACU90959; ACU90959; Dbac_2884.
KEGGidba:Dbac_2884.
PATRICi21708240. VBIDesBac69216_2937.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001629 Genomic DNA. Translation: ACU90959.1.
RefSeqiYP_003159375.1. NC_013173.1.

3D structure databases

ProteinModelPortaliC7LUP4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi525897.Dbac_2884.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACU90959; ACU90959; Dbac_2884.
KEGGidba:Dbac_2884.
PATRICi21708240. VBIDesBac69216_2937.

Phylogenomic databases

eggNOGiCOG1088.
HOGENOMiHOG000168006.
KOiK01710.
OMAiGFIASHM.
OrthoDBiEOG6PZXCX.

Enzyme and pathway databases

BioCyciDBAC525897:GI50-2946-MONOMER.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR005888. dTDP_Gluc_deHydtase.
IPR001509. Epimerase_deHydtase_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR10366:SF41. PTHR10366:SF41. 1 hit.
PfamiPF01370. Epimerase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01181. dTDP_gluc_dehyt. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 4028 / VKM B-1378Imported.

Entry informationi

Entry nameiC7LUP4_DESBD
AccessioniPrimary (citable) accession number: C7LUP4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: April 29, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.