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C7LGT1 (C7LGT1_BRUMC) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323 EMBL ACU49219.1
Ordered Locus Names:BMI_II78
OrganismBrucella microti (strain CCM 4915) [Complete proteome] [HAMAP]
Taxonomic identifier568815 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2221Iron By similarity HAMAP MF_00323
Metal binding3031Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
C7LGT1 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 262ACF5A89B7F639

FASTA35240,085
        10         20         30         40         50         60 
MSGTDKVRVN VSQTAQTPLH TSVKLPKVGV LLVNLGTPDG TSYGPMRRYL AEFLSDRRVI 

        70         80         90        100        110        120 
EWSRLIWYPI LYGIVLNTRP RRSGRLYDRI WNHENNESPL RTYTRAQGEK LAKALSDQPN 

       130        140        150        160        170        180 
VVVDWAMRYG QPSIESITDR LLQQGCERIV IFPLYPQYSA TTTATVNDKF FEALMKKRFM 

       190        200        210        220        230        240 
PAIRTVPSYE AEPVYIDALA RSVEKHLATL SFKPEVILTS YHGIPKSYSD KGDPYRQQCL 

       250        260        270        280        290        300 
ETTRLLRERL GLGEDEMRAT FQSRFGPEEW LQPYTDETVK ELAKNGVKSV AVLNPGFVAD 

       310        320        330        340        350 
CLETVDEIGN EAAEEFLENG GENFSHIPCL NDSEEGMKVI ETLVRRELLG WV

« Hide

References

[1]"Brucella microti: the genome sequence of an emerging pathogen."
Audic S., Lescot M., Claverie J.-M., Scholz H.C.
BMC Genomics 10:352-352(2009) [PubMed: 19653890] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001579 Genomic DNA. Translation: ACU49219.1.
RefSeqYP_003104881.1. NC_013118.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC7LGT1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8317854.
GenomeReviewsGene locus BMI_II78 in contig CP001579_GR.
KEGGbmr:BMI_II78.
PATRIC17802654. VBIBruMic92249_0075.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMATIEEIGM.
ProtClustDBPRK00035.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC7LGT1_BRUMC
AccessionPrimary (citable) accession number: C7LGT1
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: December 14, 2011
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info