C7LGH1 (C7LGH1_BRUMC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Homoserine kinase HAMAP MF_00301
Short name=HK HAMAP MF_00301
Short name=HSK HAMAP MF_00301
EC=2.7.1.39 HAMAP MF_00301

Gene names

Name:	thrB HAMAP MF_00301 EMBL ACU47486.1
Ordered Locus Names:	BMI_I478

Organism

Brucella microti (strain CCM 4915) [Complete proteome] [HAMAP]

Taxonomic identifier

568815 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	326 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-homoserine = ADP + O-phospho-L-homoserine. HAMAP MF_00301 SAAS SAAS002575
Pathway	Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5. HAMAP MF_00301 SAAS SAAS002575
Sequence similarities	Belongs to the pseudomonas-type thrB family. HAMAP MF_00301

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Threonine biosynthesis HAMAP MF_00301 SAAS SAAS002575
Ligand	ATP-binding HAMAP MF_00301 SAAS SAAS002575 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00301 SAAS SAAS002575 EMBL ACU47486.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	threonine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW homoserine kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C7LGH1 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: 1543E87591431AE6	FASTA	326	36,629
	10 20 30 40 50 60 MAVYTDINEI ELGAFLRHYD IGTLTSYKGI AEGVENSNYL LHTSSGSFIL TLYEKRTNRE 70 80 90 100 110 120 DLPFFLGLMQ HLAKRGLECP QPVVRNDGAM IGQLAGRPAA IVTFLEGMWM RRPTVAHCEA 130 140 150 160 170 180 VGEGLAHMHL AGADFPMRRR NGLTLPDWRP LWNLSRKCAD TVERGLVAET EADLDFLEKN 190 200 210 220 230 240 WPADLPQGVI HADLFPDNAF FLGDRLSGFI DFYFACTDIL AYDVAVCLNA WCFEKDFSYN 250 260 270 280 290 300 RTKGAALLRG YTSVRPLSEA EADALPVLAR GAAVRFMLTR LYDWLTVPAG SFVVKKDPME 310 320 YVRRMRFHRQ IESAAEYGLE MQGVAA

References

[1]	"Brucella microti: the genome sequence of an emerging pathogen." Audic S., Lescot M., Claverie J.-M., Scholz H.C. BMC Genomics 10:352-352(2009) [PubMed: 19653890] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001578 Genomic DNA. Translation: ACU47486.1.
RefSeq	YP_003106435.1. NC_013119.1.
3D structure databases
ProteinModelPortal	C7LGH1.
SMR	C7LGH1. Positions 5-319.
ModBase	Search...
Protein-protein interaction databases
STRING	C7LGH1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8320043.
GenomeReviews	Gene locus BMI_I478 in contig CP001578_GR.
KEGG	bmr:BMI_I478.
PATRIC	17805943. VBIBruMic92249_1693.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	ICLNAWC.
ProtClustDB	PRK05231.
Family and domain databases
HAMAP	MF_00301. Homoser_kinase_2. [Tree]
InterPro	IPR002575. Aminoglycoside_PTrfase. IPR005280. Homoserine_kinase_ThrB. IPR011009. Kinase-like_dom. [Graphical view]
KO	K02204.
Pfam	PF01636. APH. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
TIGRFAMs	TIGR00938. ThrB_alt. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C7LGH1_BRUMC

Accession

Primary (citable) accession number: C7LGH1

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)