C7LEW1 (C7LEW1_BRUMC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosyl-ATP pyrophosphatase HAMAP MF_01020
Short name=PRA-PH HAMAP MF_01020
EC=3.6.1.31 HAMAP MF_01020

Gene names

Name:	hisE HAMAP MF_01020 EMBL ACU49046.1
Ordered Locus Names:	BMI_I2108

Organism

Brucella microti (strain CCM 4915) [Complete proteome] [HAMAP]

Taxonomic identifier

568815 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	107 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(5-phosphoribosyl)-ATP + H2O = 1-(5-phosphoribosyl)-AMP + diphosphate. HAMAP MF_01020 SAAS SAAS008179
Pathway	Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9. HAMAP MF_01020 SAAS SAAS008179
Subcellular location	Cytoplasm By similarity HAMAP MF_01020.
Sequence similarities	Belongs to the PRA-PH family. HAMAP MF_01020

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Histidine biosynthesis HAMAP MF_01020 SAAS SAAS008179
Cellular component	Cytoplasm HAMAP MF_01020
Ligand	ATP-binding HAMAP MF_01020 SAAS SAAS008179 Nucleotide-binding
Molecular function	Hydrolase HAMAP MF_01020 SAAS SAAS008179 EMBL ACU49046.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosyl-ATP diphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C7LEW1 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: 4335A80E49ACB391	FASTA	107	11,253
	10 20 30 40 50 60 MSQFTLADLE RIVAERASVT DGTSYTASLV AKGQPKAAQK LGEEAVETVI AAVSGDRAGV 70 80 90 100 VSESADLLYH LAVVWNIAGV ALEDVLQELQ RRTAQTGLAE KASRPKG

References

[1]	"Brucella microti: the genome sequence of an emerging pathogen." Audic S., Lescot M., Claverie J.-M., Scholz H.C. BMC Genomics 10:352-352(2009) [PubMed: 19653890] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001578 Genomic DNA. Translation: ACU49046.1.
RefSeq	YP_003107995.1. NC_013119.1.
3D structure databases
ProteinModelPortal	C7LEW1.
ModBase	Search...
Protein-protein interaction databases
STRING	C7LEW1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8321668.
GenomeReviews	Gene locus BMI_I2108 in contig CP001578_GR.
KEGG	bmr:BMI_I2108.
PATRIC	17809262. VBIBruMic92249_3309.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	ETVMAAK.
ProtClustDB	PRK00400.
Family and domain databases
HAMAP	MF_01020. HisE. [Tree]
InterPro	IPR008179. PRib-ATP_PPHydrolase. IPR021130. PRib-ATP_PPHydrolase-like. [Graphical view]
KO	K01523.
Pfam	PF01503. PRA-PH. 1 hit. [Graphical view]
TIGRFAMs	TIGR03188. Histidine_hisI. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C7LEW1_BRUMC

Accession

Primary (citable) accession number: C7LEW1

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	December 14, 2011
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)