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C7LCI5

- C7LCI5_BRUMC

UniProt

C7LCI5 - C7LCI5_BRUMC

Protein

Elongation factor Tu

Gene

tuf-1

Organism
Brucella microti (strain CCM 4915)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (13 Oct 2009)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi76 – 805GTPUniRule annotation
    Nucleotide bindingi131 – 1344GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported, HydrolaseImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBMIC568815:GJUE-1243-MONOMER.
    BMIC568815:GJUE-1258-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tuf-1Imported
    Synonyms:tufUniRule annotation, tuf-2Imported
    Ordered Locus Names:BMI_I1246Imported, BMI_I1261Imported
    OrganismiBrucella microti (strain CCM 4915)Imported
    Taxonomic identifieri568815 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000002188: Chromosome 1

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi568815.BMI_I1261.

    Structurei

    3D structure databases

    ProteinModelPortaliC7LCI5.
    SMRiC7LCI5. Positions 2-390.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0050.
    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiGTEMCMP.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C7LCI5-1 [UniParc]FASTAAdd to Basket

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    MAKSKFERTK PHVNIGTIGH VDHGKTSLTA AITKFFGEFK AYDQIDAAPE    50
    ERARGITIST AHVEYETANR HYAHVDCPGH ADYVKNMITG AAQMDGAILV 100
    VSAADGPMPQ TREHILLARQ VGVPAIVVFL NKCDQVDDAE LLELVELEVR 150
    ELLSKYEFPG DEIPIIKGSA LAALEDSSKE LGEDAIRNLM DAVDSYIPTP 200
    ERPIDQPFLM PIEDVFSISG RGTVVTGRVE RGIVKVGEEV EIVGIKATTK 250
    TTVTGVEMFR KLLDQGQAGD NIGALIRGVG REDVERGQVL CKPGSVKPHT 300
    KFKAEAYILT KDEGGRHTPF FTNYRPQFYF RTTDVTGVVT LPAGTEMVMP 350
    GDNVAMDVTL IVPIAMEEKL RFAIREGGRT VGAGIVSSII E 391
    Length:391
    Mass (Da):42,605
    Last modified:October 13, 2009 - v1
    Checksum:iED4CDF37183A900E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001578 Genomic DNA. Translation: ACU48220.1.
    CP001578 Genomic DNA. Translation: ACU48234.1.
    RefSeqiYP_003107169.1. NC_013119.1.
    YP_003107183.1. NC_013119.1.

    Genome annotation databases

    EnsemblBacteriaiACU48220; ACU48220; BMI_I1246.
    ACU48234; ACU48234; BMI_I1261.
    GeneIDi8320807.
    8320822.
    KEGGibmr:BMI_I1246.
    bmr:BMI_I1261.
    PATRICi17807506. VBIBruMic92249_2460.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001578 Genomic DNA. Translation: ACU48220.1 .
    CP001578 Genomic DNA. Translation: ACU48234.1 .
    RefSeqi YP_003107169.1. NC_013119.1.
    YP_003107183.1. NC_013119.1.

    3D structure databases

    ProteinModelPortali C7LCI5.
    SMRi C7LCI5. Positions 2-390.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 568815.BMI_I1261.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACU48220 ; ACU48220 ; BMI_I1246 .
    ACU48234 ; ACU48234 ; BMI_I1261 .
    GeneIDi 8320807.
    8320822.
    KEGGi bmr:BMI_I1246.
    bmr:BMI_I1261.
    PATRICi 17807506. VBIBruMic92249_2460.

    Phylogenomic databases

    eggNOGi COG0050.
    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi GTEMCMP.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci BMIC568815:GJUE-1243-MONOMER.
    BMIC568815:GJUE-1258-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Brucella microti: the genome sequence of an emerging pathogen."
      Audic S., Lescot M., Claverie J.-M., Scholz H.C.
      BMC Genomics 10:352-352(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CCM 4915Imported.

    Entry informationi

    Entry nameiC7LCI5_BRUMC
    AccessioniPrimary (citable) accession number: C7LCI5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 13, 2009
    Last sequence update: October 13, 2009
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3