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C7KW60

- C7KW60_ACEPA

UniProt

C7KW60 - C7KW60_ACEPA

Protein

Alanine racemase

Gene

APA42C_24990

Organism
Acetobacter pasteurianus IFO 3283-01-42C
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 33 (01 Oct 2014)
      Sequence version 1 (13 Oct 2009)
      Previous versions | rss
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    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei52 – 521Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei151 – 1511SubstrateUniRule annotation
    Active sitei273 – 2731Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei321 – 3211Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciAPAS634458:GL78-2432-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    ORF Names:APA42C_24990Imported
    OrganismiAcetobacter pasteurianus IFO 3283-01-42CImported
    Taxonomic identifieri634458 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeAcetobacter
    ProteomesiUP000000952: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei52 – 521N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliC7KW60.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C7KW60-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVVNTVSSS ARTLWPASRA GAVLTVNLSA IAENYRYLKS RLGKTACAAV    50
    VKADAYGLGV AQVAPVLEKA GAEHFFVAHV DEGLALRPFL SPHTSVTVLH 100
    GPRPDAAEVC VRNNLRPVLN SLEQVAVLRD LAAKMDKPLD VAIQLDTGMS 150
    RFGLSEADIH KLVASPELLK GLFVSLVMSH LACADTPQNP ANTMQRERFE 200
    AYARILPQAA LSLSASSGIF LGPQFHFDLV RPGAALYGVA PQNEGDNPLK 250
    PVVGLQAHIL QIRHLSKGDR VGYGLTWQAH GPCRVATIAT GYADGFARAG 300
    AAAGCAWYKG YRLPILGRIS MDSMTVDLSA VPEGLLEEDS MVELLNESYG 350
    VDAVAKAEGT IGYEVLTSLG RRYHRVYAAA A 381
    Length:381
    Mass (Da):40,610
    Last modified:October 13, 2009 - v1
    Checksum:iB5110A7F954991C2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP011163 Genomic DNA. Translation: BAI18826.1.
    RefSeqiYP_005502898.1. NC_017150.1.

    Genome annotation databases

    EnsemblBacteriaiBAI18826; BAI18826; APA42C_24990.
    GeneIDi12091862.
    KEGGiapw:APA42C_24990.
    PATRICi36849323. VBIAcePas142730_2517.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP011163 Genomic DNA. Translation: BAI18826.1 .
    RefSeqi YP_005502898.1. NC_017150.1.

    3D structure databases

    ProteinModelPortali C7KW60.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAI18826 ; BAI18826 ; APA42C_24990 .
    GeneIDi 12091862.
    KEGGi apw:APA42C_24990.
    PATRICi 36849323. VBIAcePas142730_2517.

    Phylogenomic databases

    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci APAS634458:GL78-2432-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: IFO 3283Imported.

    Entry informationi

    Entry nameiC7KW60_ACEPA
    AccessioniPrimary (citable) accession number: C7KW60
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 13, 2009
    Last sequence update: October 13, 2009
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3