Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

C7KK71 (C7KK71_ACEPA) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
ORF Names:APA32_19020 EMBL BAI15269.1
OrganismAcetobacter pasteurianus IFO 3283-32 [Complete proteome] EMBL BAI15269.1
Taxonomic identifier634457 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeAcetobacter

Protein attributes

Sequence length312 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain106 – 306201ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding132 – 18554ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2561Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2731Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2731Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2751Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
C7KK71 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 80A0E740C6F70EC0

FASTA31232,944
        10         20         30         40         50         60 
MNAPKRVTVL MGGMSSERVV SLSSGQGVAE ALRSKGYDVC TLDAQADLAT LVEALNTQKP 

        70         80         90        100        110        120 
DVVFNALHGR FGEDGCIQGI LDWMGIPYTH SGIRASATAM DKAAARAIFQ TAGLPVAEGM 

       130        140        150        160        170        180 
VVDIATLAHA DPLPTPYVVK PLNEGSSVGV SIVRTGSNTR ADIVKNWTYG PQALVEAFIP 

       190        200        210        220        230        240 
GREITVGVMG DRALTITDIT PTGTGHDFYD YDSKYQVGGS AHVLPAQIDA ASAKLALEVA 

       250        260        270        280        290        300 
VKAHQALGCS GASRSDFRLD DTNPDQPHLI LLEVNTQPGM TATSLLPEQA AYCGISYPEL 

       310 
CAWLVEQATC RQ 

« Hide

References

[1]"Whole-genome analyses reveal genetic instability of Acetobacter pasteurianus."
Azuma Y., Hosoyama A., Matsutani M., Furuya N., Horikawa H., Harada T., Hirakawa H., Kuhara S., Matsushita K., Fujita N., Shirai M.
Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: IFO 3283 EMBL BAI15269.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP011156 Genomic DNA. Translation: BAI15269.1.
RefSeqYP_005484329.1. NC_017111.1.

3D structure databases

ProteinModelPortalC7KK71.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAI15269; BAI15269; APA32_19020.
GeneID12070651.
KEGGapz:APA32_19020.
PATRIC36887123. VBIAcePas144801_1981.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycAPAS634457:GL7K-1905-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC7KK71_ACEPA
AccessionPrimary (citable) accession number: C7KK71
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: June 11, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)