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C7JX05

- C7JX05_ACEPA

UniProt

C7JX05 - C7JX05_ACEPA

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Protein
Acetyltransferase component of pyruvate dehydrogenase complex
Gene
APA07_12160
Organism
Acetobacter pasteurianus IFO 3283-07
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 By similarity.UniRule annotation

Catalytic activityi

Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine.UniRule annotation

Cofactori

Binds 1 lipoyl cofactor covalently By similarity.UniRule annotation
Binds 2 lipoyl cofactors covalently By similarity.UniRule annotation
Binds 3 lipoyl cofactors covalently By similarity.UniRule annotation

GO - Molecular functioni

  1. dihydrolipoyllysine-residue acetyltransferase activity Source: InterPro

GO - Biological processi

  1. pyruvate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

BioCyciAPAS634454:GL7B-1218-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.12UniRule annotation)
Gene namesi
ORF Names:APA07_12160Imported
OrganismiAcetobacter pasteurianus IFO 3283-07Imported
Taxonomic identifieri634454 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeAcetobacter
ProteomesiUP000000949: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. pyruvate dehydrogenase complex Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliC7JX05.

Family & Domainsi

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation
Contains 1 lipoyl-binding domain.UniRule annotation

Keywords - Domaini

LipoylUniRule annotationSAAS annotations

Phylogenomic databases

KOiK00627.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR006257. LAT1.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMiSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
TIGRFAMsiTIGR01349. PDHac_trf_mito. 1 hit.
PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
PS00189. LIPOYL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C7JX05-1 [UniParc]FASTAAdd to Basket

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MATEILMPAL SPTMTEGKLA RWLKKEGDTV NSGDVLAEIE TDKATMEVEA    50
IEEGILGRIL IQEGAEGVAV NTPIAILVEE GEAVPDNIDT PKNVASAEPA 100
PVPQPVASAP VAAQAAPAQR ADKPVGRVVA SPLARRIARQ KNIDLAAIKG 150
TGPNGRIVKR DVEAALNKAP SAGQVASALP ASGGSSAVPH TTMRKVIARR 200
LSESKATIPH FYVSIDVELD ALLALRAQLN AMSPAEGADA FKLSVNDMLI 250
KASAVALKQV PEVNASYTED AMILHEDADI SVAVSLDDGL ITPIVKQADR 300
KSLKDISQEA KDLIARARAG KLKPEEFQGG TFSISNMGMY GVKDFAAIVN 350
PPQAAILAIA AGKKQAVVKG NELAIATVMT VTLSVDHRVV DGAAAARWLS 400
AFRTAVESPL SLVL 414
Length:414
Mass (Da):43,264
Last modified:October 13, 2009 - v1
Checksum:i70CEC00BE9637960
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP011135 Genomic DNA. Translation: BAI05462.1.
RefSeqiYP_005486950.1. NC_017121.1.

Genome annotation databases

GeneIDi12074624.
KEGGiapu:APA07_12160.
PATRICi36859655. VBIAcePas143188_1288.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP011135 Genomic DNA. Translation: BAI05462.1 .
RefSeqi YP_005486950.1. NC_017121.1.

3D structure databases

ProteinModelPortali C7JX05.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 12074624.
KEGGi apu:APA07_12160.
PATRICi 36859655. VBIAcePas143188_1288.

Phylogenomic databases

KOi K00627.

Enzyme and pathway databases

BioCyci APAS634454:GL7B-1218-MONOMER.

Family and domain databases

Gene3Di 3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProi IPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR006257. LAT1.
IPR011053. Single_hybrid_motif.
[Graphical view ]
Pfami PF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view ]
SUPFAMi SSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
TIGRFAMsi TIGR01349. PDHac_trf_mito. 1 hit.
PROSITEi PS50968. BIOTINYL_LIPOYL. 1 hit.
PS00189. LIPOYL. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Whole-genome analyses reveal genetic instability of Acetobacter pasteurianus."
    Azuma Y., Hosoyama A., Matsutani M., Furuya N., Horikawa H., Harada T., Hirakawa H., Kuhara S., Matsushita K., Fujita N., Shirai M.
    Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: IFO 3283Imported.

Entry informationi

Entry nameiC7JX05_ACEPA
AccessioniPrimary (citable) accession number: C7JX05
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: July 9, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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