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C7JX05

- C7JX05_ACEPA

UniProt

C7JX05 - C7JX05_ACEPA

Protein

Acetyltransferase component of pyruvate dehydrogenase complex

Gene

APA07_12160

Organism
Acetobacter pasteurianus IFO 3283-07
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (13 Oct 2009)
      Previous versions | rss
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    Functioni

    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.UniRule annotation

    Catalytic activityi

    Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine.UniRule annotation

    Cofactori

    Binds 1 lipoyl cofactor covalently.UniRule annotation
    Binds 2 lipoyl cofactors covalently.UniRule annotation
    Binds 3 lipoyl cofactors covalently.UniRule annotation

    GO - Molecular functioni

    1. dihydrolipoyllysine-residue acetyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pyruvate metabolic process Source: InterPro

    Keywords - Molecular functioni

    AcyltransferaseUniRule annotation, Transferase

    Enzyme and pathway databases

    BioCyciAPAS634454:GL7B-1218-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.12UniRule annotation)
    Gene namesi
    ORF Names:APA07_12160Imported
    OrganismiAcetobacter pasteurianus IFO 3283-07Imported
    Taxonomic identifieri634454 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeAcetobacter
    ProteomesiUP000000949: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. pyruvate dehydrogenase complex Source: InterPro

    Structurei

    3D structure databases

    ProteinModelPortaliC7JX05.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation
    Contains 1 lipoyl-binding domain.UniRule annotation

    Keywords - Domaini

    LipoylUniRule annotationSAAS annotation

    Phylogenomic databases

    KOiK00627.

    Family and domain databases

    Gene3Di3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
    IPR001078. 2-oxoacid_DH_actylTfrase.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR006257. LAT1.
    IPR011053. Single_hybrid_motif.
    [Graphical view]
    PfamiPF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 1 hit.
    PF02817. E3_binding. 1 hit.
    [Graphical view]
    SUPFAMiSSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 1 hit.
    TIGRFAMsiTIGR01349. PDHac_trf_mito. 1 hit.
    PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
    PS00189. LIPOYL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C7JX05-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATEILMPAL SPTMTEGKLA RWLKKEGDTV NSGDVLAEIE TDKATMEVEA    50
    IEEGILGRIL IQEGAEGVAV NTPIAILVEE GEAVPDNIDT PKNVASAEPA 100
    PVPQPVASAP VAAQAAPAQR ADKPVGRVVA SPLARRIARQ KNIDLAAIKG 150
    TGPNGRIVKR DVEAALNKAP SAGQVASALP ASGGSSAVPH TTMRKVIARR 200
    LSESKATIPH FYVSIDVELD ALLALRAQLN AMSPAEGADA FKLSVNDMLI 250
    KASAVALKQV PEVNASYTED AMILHEDADI SVAVSLDDGL ITPIVKQADR 300
    KSLKDISQEA KDLIARARAG KLKPEEFQGG TFSISNMGMY GVKDFAAIVN 350
    PPQAAILAIA AGKKQAVVKG NELAIATVMT VTLSVDHRVV DGAAAARWLS 400
    AFRTAVESPL SLVL 414
    Length:414
    Mass (Da):43,264
    Last modified:October 13, 2009 - v1
    Checksum:i70CEC00BE9637960
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP011135 Genomic DNA. Translation: BAI05462.1.
    RefSeqiYP_005486950.1. NC_017121.1.

    Genome annotation databases

    GeneIDi12074624.
    KEGGiapu:APA07_12160.
    PATRICi36859655. VBIAcePas143188_1288.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP011135 Genomic DNA. Translation: BAI05462.1 .
    RefSeqi YP_005486950.1. NC_017121.1.

    3D structure databases

    ProteinModelPortali C7JX05.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 12074624.
    KEGGi apu:APA07_12160.
    PATRICi 36859655. VBIAcePas143188_1288.

    Phylogenomic databases

    KOi K00627.

    Enzyme and pathway databases

    BioCyci APAS634454:GL7B-1218-MONOMER.

    Family and domain databases

    Gene3Di 3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProi IPR003016. 2-oxoA_DH_lipoyl-BS.
    IPR001078. 2-oxoacid_DH_actylTfrase.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR006257. LAT1.
    IPR011053. Single_hybrid_motif.
    [Graphical view ]
    Pfami PF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 1 hit.
    PF02817. E3_binding. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 1 hit.
    TIGRFAMsi TIGR01349. PDHac_trf_mito. 1 hit.
    PROSITEi PS50968. BIOTINYL_LIPOYL. 1 hit.
    PS00189. LIPOYL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: IFO 3283Imported.

    Entry informationi

    Entry nameiC7JX05_ACEPA
    AccessioniPrimary (citable) accession number: C7JX05
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 13, 2009
    Last sequence update: October 13, 2009
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3