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Protein

NADH-cytochrome b5 reductase

Gene

MCR1

Organism
Saccharomyces cerevisiae (strain JAY291) (Baker's yeast)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

NADH + 2 ferricytochrome b5 = NAD+ + H+ + 2 ferrocytochrome b5.UniRule annotation

Cofactori

FADUniRule annotationSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotation
LigandFADUniRule annotationSAAS annotation, Flavoprotein, NADUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-cytochrome b5 reductaseUniRule annotation (EC:1.6.2.2UniRule annotation)
Gene namesi
Name:MCR1Imported
ORF Names:C1Q_03402Imported
OrganismiSaccharomyces cerevisiae (strain JAY291) (Baker's yeast)Imported
Taxonomic identifieri574961 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000008073 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 31HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliC7GSN4.
SMRiC7GSN4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 155FAD-binding FR-typeInterPro annotationAdd BLAST105

Sequence similaritiesi

Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

OrthoDBiEOG092C43G8.

Family and domain databases

InterProiView protein in InterPro
IPR017927. Fd_Rdtase_FAD-bd.
IPR001709. Flavoprot_Pyr_Nucl_cyt_Rdtase.
IPR001834. NADH-Cyt_B5_reductase.
IPR008333. OxRdtase_FAD-bd_dom.
IPR001433. OxRdtase_FAD/NAD-bd.
IPR017938. Riboflavin_synthase-like_b-brl.
PfamiView protein in Pfam
PF00970. FAD_binding_6. 1 hit.
PF00175. NAD_binding_1. 1 hit.
PRINTSiPR00406. CYTB5RDTASE.
PR00371. FPNCR.
SUPFAMiSSF63380. SSF63380. 1 hit.
PROSITEiView protein in PROSITE
PS51384. FAD_FR. 1 hit.

Sequencei

Sequence statusi: Complete.

C7GSN4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSRLSRSHS KALPIALGTV AIAAATAFYF ANRNQHSFVF NESNKVFKGD
60 70 80 90 100
DKWIDLPISK IEEESHDTRR FTFKLPTEDS EMGLVLASAL FAKFVTPKGS
110 120 130 140 150
NVVRPYTPVS DLSQKGHFQL VVKHYEGGKM TSHLFGLKPN DTVSFKGPIM
160 170 180 190 200
KWKWQPNQFK SITLLGAGTG INPLYQLAHH IVENPNDKTK VNLLYGNKTP
210 220 230 240 250
QDILLRKELD ALKEKYPDKF NVTYFVDDKQ DDQDFDGEIG FISKDFIQEH
260 270 280 290 300
VPGPKESTHL FVCGPPPFMN AYSGEKKSPK DQGELIGILN NLGYSKDQVF

KF
Length:302
Mass (Da):34,108
Last modified:October 13, 2009 - v1
Checksum:iD3D68BF56E8C433B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFL01000198 Genomic DNA. Translation: EEU06187.1.

Similar proteinsi

Entry informationi

Entry nameiC7GSN4_YEAS2
AccessioniPrimary (citable) accession number: C7GSN4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: April 12, 2017
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported