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C7GL41

- YM084_YEAS2

UniProt

C7GL41 - YM084_YEAS2

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Protein

Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Gene

C1Q_01026

Organism
Saccharomyces cerevisiae (strain JAY291) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).By similarity

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei2 – 21Nucleophile; for GATase activityPROSITE-ProRule annotation

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. glutamine metabolic process Source: UniProtKB-KW
  3. UDP-N-acetylglucosamine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00113; UER00528.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC:2.6.1.16)
Short name:
GFAT
Alternative name(s):
D-fructose-6-phosphate amidotransferase
Hexosephosphate aminotransferase
Gene namesi
ORF Names:C1Q_01026
OrganismiSaccharomyces cerevisiae (strain JAY291) (Baker's yeast)
Taxonomic identifieri574961 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000008073: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 720720Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing]PRO_0000393411Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliC7GL41.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 321320Glutamine amidotransferase type-2PROSITE-ProRule annotationAdd
BLAST
Domaini393 – 532140SIS 1PROSITE-ProRule annotationAdd
BLAST
Domaini565 – 710146SIS 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 glutamine amidotransferase type-2 domain.PROSITE-ProRule annotation
Contains 2 SIS domains.PROSITE-ProRule annotation

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

OrthoDBiEOG7034RG.

Family and domain databases

Gene3Di3.60.20.10. 2 hits.
InterProiIPR017932. GATase_2_dom.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view]
PfamiPF01380. SIS. 2 hits.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 2 hits.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C7GL41-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MCGIFGYCNF LIEKTRGEII DTLIEGLQAL EYKEYDSSGI SIQGDELKSL
60 70 80 90 100
NIYKQTGKIS SLKEEIDLYN LNKNLPFISH CGIAHTRRAT HGGLRRANCH
110 120 130 140 150
PHNSDPSNEF VVVHNGVITN FANLKALLVA KGYVFKSDTD TECIPKLYKH
160 170 180 190 200
IYDTSIELGY NLDFHVLTNL VLKELEGSYG LLCTSSHFPD EVVAARKGSP
210 220 230 240 250
LVIGVKGKTD MDVNFVEVEY LDQEEDYLKL NTQTKSSGNV LAAAPVKYNT
260 270 280 290 300
CLRKSPPLRS QYLRNSTTST FNHGSSTETP AENGLPRPME FYLSSDCASL
310 320 330 340 350
ARYVSKVVYL EDNDTAHIYD GELHIHCSKI GSEDFSFRTV QKLELELSKI
360 370 380 390 400
KKGPYDNFMQ KEIYEQCETT KNVMRGRVDA FTNRVVLGGL ENWLTELRRA
410 420 430 440 450
KRIIMIASKS SFHSCLAARP IFEELMEVPV NVELALDFVD RNCCIFRNDV
460 470 480 490 500
CIFVSRSGET TDTINALNYC IKKEAVTIGV VNCSGSSISR FTHCGVHTNT
510 520 530 540 550
GPEKGIATTK SYTSQYIALV MIALWMSEDL VSKIERRKEI IQALTIVPSQ
560 570 580 590 600
IKEVLELEPL IIELCDKKLK QHDTFLLLGR GYQFASALEG ASKMKEISYV
610 620 630 640 650
HSESILTDEL GHRVLAVTSD NPPIIAFATK DAFSPKIASC IDQIIERKGN
660 670 680 690 700
PIIICNKGHK IWEQDKQKGN VVTLEVPQTV DCLQGILNVI PLQLISYWLA
710 720
IKKDIGVDLP RDSAMSAPDI
Length:720
Mass (Da):80,561
Last modified:April 20, 2010 - v2
Checksum:iFCDCAB9E434094A6
GO

Sequence cautioni

The sequence EEU08477.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFL01000033 Genomic DNA. Translation: EEU08477.1. Different initiation.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFL01000033 Genomic DNA. Translation: EEU08477.1 . Different initiation.

3D structure databases

ProteinModelPortali C7GL41.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

OrthoDBi EOG7034RG.

Enzyme and pathway databases

UniPathwayi UPA00113 ; UER00528 .

Family and domain databases

Gene3Di 3.60.20.10. 2 hits.
InterProi IPR017932. GATase_2_dom.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view ]
Pfami PF01380. SIS. 2 hits.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 2 hits.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JAY291.

Entry informationi

Entry nameiYM084_YEAS2
AccessioniPrimary (citable) accession number: C7GL41
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 1, 2014
This is version 25 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3