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C7FFR5 (C7FFR5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:ESR1 EMBL ACU29456.1
OrganismHomo sapiens (Human) EMBL ACU29456.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length46 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains nuclear receptor DNA-binding domain. SAAS SAAS001628

Ontologies

Keywords
   Biological processTranscription
Transcription regulation SAAS SAAS001628
   Cellular componentNucleus SAAS SAAS001628
   DomainZinc-finger SAAS SAAS001628
   LigandDNA-binding SAAS SAAS001628
Metal-binding
Zinc
   Molecular functionReceptor EMBL ACU29456.1
Gene Ontology (GO)
   Biological_processandrogen metabolic process

Inferred from electronic annotation. Source: Ensembl

antral ovarian follicle growth

Inferred from electronic annotation. Source: Ensembl

cellular response to estrogen stimulus

Inferred from electronic annotation. Source: Ensembl

epithelial cell development

Inferred from electronic annotation. Source: Ensembl

epithelial cell proliferation involved in mammary gland duct elongation

Inferred from electronic annotation. Source: Ensembl

male gonad development

Inferred from electronic annotation. Source: Ensembl

mammary gland alveolus development

Inferred from electronic annotation. Source: Ensembl

mammary gland branching involved in pregnancy

Inferred from electronic annotation. Source: Ensembl

positive regulation of fibroblast proliferation

Inferred from electronic annotation. Source: Ensembl

positive regulation of transcription from RNA polymerase II promoter

Inferred from electronic annotation. Source: Ensembl

prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis

Inferred from electronic annotation. Source: Ensembl

prostate epithelial cord elongation

Inferred from electronic annotation. Source: Ensembl

regulation of apoptotic process

Inferred from electronic annotation. Source: Ensembl

regulation of branching involved in prostate gland morphogenesis

Inferred from electronic annotation. Source: Ensembl

uterus development

Inferred from electronic annotation. Source: Ensembl

vagina development

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: Ensembl

nucleus

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionchromatin binding

Inferred from electronic annotation. Source: Ensembl

ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity

Inferred from electronic annotation. Source: Ensembl

sequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL ACU29456.1

Sequences

Sequence LengthMass (Da)Tools
C7FFR5 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: 076A9107F1505735

FASTA465,304
        10         20         30         40 
GYHYGVWSCE GCKAFFKRSI QGHNDYMCPA TNQCTIDKNR RKSCQA 

« Hide

References

[1]"Decreased alternative splicing of estrogen receptor-alpha mRNA in the Alzheimer's disease brain."
Ishunina T.A., Swaab D.F.
Neurobiol. Aging 33:286-296(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: White matter of brain EMBL ACU29456.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
GQ366704 mRNA. Translation: ACU29456.1.
UniGeneHs.208124.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Gene expression databases

ArrayExpressC7FFR5.
BgeeC7FFR5.

Family and domain databases

Gene3D3.30.50.10. 1 hit.
InterProIPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamPF00105. zf-C4. 1 hit.
[Graphical view]
SMARTSM00399. ZnF_C4. 1 hit.
[Graphical view]
PROSITEPS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSESR1. human.
NextBio35483635.

Entry information

Entry nameC7FFR5_HUMAN
AccessionPrimary (citable) accession number: C7FFR5
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: April 16, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.